Time does not stand still, and all biological forms of life on Earth are subject to senile changes. The emerging processes of aging determine the appearance of dissatisfaction with one's own body and those around it, the occurrence of rapid breathing during movement, shortness of breath, stooped posture and stiffness of movements. In addition, vision deteriorates.
There is an opinion, which, by the way, is very common, that the aging process is not something to stop, but it is almost impossible to slow down. Professor Skulachev, whose eye drops have a truly miraculous effect, holds a different point of view.
Of course, aging is a natural process, but why can't it be slowed down? Aging occurs for a reason. There is a strong opinion among scientists involved in the aging processes of the human body that a special program is written in our DNA chain that is responsible for aging processes throughout the body. When a certain age is reached, this program is activated, which ultimately leads to the inevitable - death.
What is dangerous for aging eyes
Violation of the processes of visual perception is one of the signs of the aging process. No, of course, you can meet people with a colossal state of health, which is enough to actively and fully resist all kinds of diseases of senile age, but if a person suddenly loses his eyesight or if it drastically worsens, then even such a โheroโ becomes doomed to disability.
The vast majority of ophthalmic diseases develop very slowly over time. With age, the lacrimal gland works worse, and this entails a decrease in the production and quality of the tear itself. This becomes noticeable after reaching the age of 40, but can also happen after 30.
It seems to be so what? It is quite natural that with age the eye protective film becomes thinner, more often corneal microtraumas and injuries, inflammatory diseases occur, and eye fatigue occurs faster. In the future, such micro-changes are the foundation for the development of more formidable diseases, such as cataracts, increased intraocular pressure with the development of glaucoma, degenerative changes in the retina and optic nerve may begin with progressive loss of vision. However, do not be afraid that these diseases can manifest all at once. Their development is slow and gradual.
This prompted what Professor Skulachev decided to create eye drops. Reviews today about them are the most positive. A very large, if not huge, number of ophthalmic patients got a chance to look at the world again with clear eyes without surgery. And all thanks to the fact that Professor Skulachev invented eye drops, the price of which is more than affordable.
Mitochondrial Antioxidants
At Moscow State University. Since 2005, Lomonosov launched a research project to develop drugs designed to delay activation and slow down the aging program. Under the strict guidance of V.P. Skulachev, academician of the Russian Academy of Sciences, a biochemist scientist who has been studying processes in the mitochondria for more than forty years, the newest type of biologically active substances - mitochondrial antioxidants, was invented.
Carrying out the first studies after the invention of this type of chemical substances, scientists discovered that mitochondrial antioxidants slowed down, and in some cases reversed, the development of ophthalmic diseases in animals under experimental conditions. A few years later, a great deal of work was done on the invention of a new medicine based on mitochondrial antioxidants, and Professor Skulachev introduced eye drops under the name "Visomitin".
Let's look at one of the very first signs of manifestation of eye aging - age-related disorders of the functioning of the lacrimal gland. What happens with age? With age, there is a decrease in the quantitative and qualitative characteristics of the lacrimal fluid and, as a result, the development of dry eye syndrome. It manifests itself with initial sensations of discomfort in the eyes, a sensation of grains of sand or a small foreign body, and with the gradual progression of the disease, more serious consequences may occur.
Note that drops from cataracts currently exist in the pharmaceutical market in large numbers. The number of drugs aimed at treating symptomatic manifestations with a dry eye is also large, but almost all of them (or the vast majority of them) are a synthetic analogue of human tear fluid. Their main disadvantage is that the patient has to use these drugs from 10 to 20-25 times a day, since the use is simply aimed at restoring the normal content of tear fluid in the eye.
Laboratory and clinical trials
The newest Visomitin drops are fundamentally different in principle of action from similar drugs used to treat dry eyes. They act on the very cause of the disease, improving the functioning of the lacrimal gland and stopping its degenerative changes. In addition, these drops have a similar effect, like cataract drops based on an artificial tear.
This circumstance is not just a theoretical statement, but a really established fact. Professor Skulachev examined eye drops in every way on animals, and also conducted clinical trials of the drug in many eye centers: at the Department of Ophthalmology (Russian State Medical University) and at the Helmholtz Scientific Research Institute of Eye Diseases.
The results obtained in these studies and clinical trials are quite encouraging. Professor Skulachev, whose eye drops are called Visomitin, says that they are far superior in effectiveness to similar drugs used to treat and eliminate signs of dry eye syndrome. Moreover, it is worth noting that there were no side effects associated with the use of these drops in patients.
Based on the results of these studies, the drug was registered with the Ministry of Health and Social Development in December 2011 as a keratoprotective drug called Visomitin, or Skulachev's eye drops. Where to buy the drug today? Since the summer of 2012, he appeared in the country's retail pharmacy chain.
Of course, like any other new drug with a previously unknown active ingredient, Visomitin is only available on prescription. Is it possible to buy Skulachev eye drops without it? Where to buy them if there is no recipe? Do not resort to gimmicks, but contact your attending ophthalmologist. The release of a prescription drug should not be attributed to disadvantages - this largely determines its purposeful purpose, which, in turn, implies a good effect from the use.
A truly unique discovery was made by Professor Skulachev. Eye drops, reviews of which are only good, really have a miraculous effect. Their implementation and clinical studies are monitored by ophthalmologists not only in Russia but also throughout the world. This drug is dedicated to individual conferences and symposia in order to convey information to each ophthalmologist.
Let us dwell in more detail on the drug "Visomitin". Instructions for use can give a lot of interesting information.
Description of the drug
This tool is an almost transparent, possibly slightly colored or slightly opalescent liquid. The active substance is plastoquinonyl decyl triphenylphosphonium bromide, which in 1 ml of the drug contains 0.155 ฮผg. Benzalkonium chloride, hypromellose, sodium chloride, etc. are used as auxiliary substances. This drug belongs to the pharmacotherapeutic group of keratoprotective agents, as well as to the group of antioxidants.
Pharmacodynamics Data
Plastoquinonyl decyl triphenylphosphonium bromide is a derivative of the plastoquinone compound, which is connected through the so-called linker chain to the triphenylphosphine residue. According to Dr. Skulachev, eye drops (the price of them due to the relative cheapness of the synthesis of this compound is not high) in nanomolar concentrations can show very high antioxidant activity with a high stimulating effect on the processes of tear formation, increase the physical stability of the formed tear film, and also have an effect on epithelialization processes.
Pharmacokinetic data
To date, it is worth saying that studies of the pharmacokinetic series have not been conducted in humans. As for preclinical studies in animals, the distribution of the active substance of drops in the body was observed within 2 days after parenteral or oral administration. The presence of plastoquinonyl decyl triphenylphosphonium bromide was recorded in the highest concentrations in the renal tissue and liver, heart tissue 1 hour after administration. It was noted that this substance was very quickly degraded by enzymes and was capable of covalent bonds with proteins.
Indications and contraindications
Drops Skulacheva "Visomitin" are prescribed for the syndrome of "dry eye", age-related changes in the lacrimal gland, computer syndrome. Based on the fact that scientific studies of the effects of the drug are still ongoing, it is also recommended for cataracts, glaucoma and complex treatment of any diseases in ophthalmology.
As Vladimir Skulachev pointed out, eye drops are contraindicated in case of hypersensitivity to the drug, as well as for children under the age of 18.
Use during pregnancy and during breastfeeding
To date, full-fledged randomized, blind, controlled trials of the drug in pregnant women, as well as in nursing mothers, have not been conducted. In view of this circumstance, the appointment of the drug during gestation is highly not recommended. If there is an acute need for an appointment in the lactation period, then breastfeeding must be stopped.
Method of use and dosage of the drug
The drug should be instilled 1-2 drops in the conjunctival sac of the patientโs eye three times a day. Depending on the severity of the symptoms and the severity of the course of the disease, the duration of the therapeutic course can be set individually by the attending ophthalmologist.
Side effects and overdose
According to scientific research, as well as clinical and laboratory tests of the drug, no side effects were detected, but allergic reactions may occur. There are no data on overdose with topical administration of the drug.
Drug interactions
There are no data on drug interactions with other drug groups. If there is a need for the simultaneous use of Visomitin with other eye drops, the interval between instillations of the eye should be at least 5 minutes.
special instructions
During clinical trials of the drug, data were obtained that โVisomitinโ is able to cause short-term accommodation disturbances with its subsequent restoration. If visual impairment is observed after using the medicine, one should refrain from driving a vehicle or mechanisms, as well as carrying out activities requiring increased attention, until the visual acuity is fully restored.
Release form
Eye drops with an active substance content of 0.155 ฮผg / ml are available in special bottles of polyethylene with a volume of 5 ml each with stoppers - droppers and screw caps. The drug is dispensed only by prescription. Keep eye drops necessary at a temperature of 2 to 8 0 C.
Where to buy medicine
It is possible to buy Vizomitin drops, the price of which is not high today, if you correlate it with the expected effect, in almost every pharmacy in Russia. The average cost in the Russian Federation of drops is about 500 rubles. The effect of the drug is simply colossal. A huge number of people got the opportunity for a clear and clear vision thanks to this tool. As Professor Skulachev pointed out, eye drops, the price of which is affordable for everyone, will have an effective therapeutic effect for those who suffer from ophthalmic diseases.
Undoubtedly, after a certain period of time, research universities will complete full-scale studies of Visomitin eye drops, and then with high probability there will be new possibilities for the use of mitochondrial antioxidants not only in the clinical practice of ophthalmology, but also in other branches of medicine.
Reviews about the drug
Numerous reviews of people who have used Visomitin eye drops are based on their action. Patients are pleased that the drug does not require frequent instillation, and with prolonged use, the frequency of its use can be reduced to once a day. According to consumers, eye problems are really being solved. They stop blushing, get tired less, swelling passes. Patients did not notice any side effects.