Most often, people consider vitamins an optional element in their daily diet. Many refer to drugs of this kind as a useful supplement in the autumn-spring period, so as not to hurt and maintain immunity. As drugs, they are not particularly perceived. In this case, there are situations when some diseases have a very strong effect on the body, suffering from a deficiency of nutrients. This is especially true for pathologies associated with vascular function and a lack of vitamins B9, B6 and B12. In this case, vitamins are transformed into medicines, in particular, this refers to Angiovit vitamins.
The drug "Angiovit"
Not so long ago, a deficiency of vitamins B9, B6 and B12 in the human body was treated with syringes with ampoules and very painful injections. If we say what Angiovit is, it’s best to say that this is a painless solution to the problem of hypovitaminosis of elements from group B, along with pyridoxine, cyanocobalamin and folic acid.
All these elements have an effect on the state of blood vessels in the human body. While taking the drug, the microcirculation of the substances of their walls, including the capillaries, is restored, strengthen and become much more resistant to external influences and damage, helping to reduce the risk of blood clots.
According to reviews, Angiovit reduces the content of a substance called homocysteine ​​in the blood. Its excessive amount in the body can lead to various pathologies of the heart or blood vessels, including myocardial infarction and stroke.
Pharmacological properties
The pharmacological effect of Angiovit vitamins is quite extensive, despite the fact that it contains only three vitamins. Vitamin B6 plays an important role in the transmission of nerve impulses, vitamin B9 takes an active part in the process of combining DNA molecules, and vitamin B12 is necessary for the implementation of blood formation processes.
According to the instructions, Angiovit belongs to the category of multivitamin complexes, which include only vitamins from group B. The drug has the ability to activate the main enzymes of methionine remethylation and transulfurization in the body, that is, cystation-B-synthetase and methylenetetrahydrofolate reductase. As a result of the activation process in the body, methionine metabolism is accelerated, which leads to a decrease in the concentration of homocysteine ​​in human blood.
An excess of this substance in the body can contribute to the development of atherosclerosis, arterial thrombosis or diabetic angiopathy. Also, hyperhomocysteinemia can cause the occurrence of chronic miscarriage and congenital abnormalities of the fetus. In addition, this phenomenon is associated with the occurrence in a person of a state of depression of various types, dementia (senile dementia) or Alzheimer's disease.
Such changes in the body can occur precisely because of a lack of three vitamins from group B. When normalizing the level of homocysteine ​​with the vitamins that make up Angiovit, atherosclerosis and thrombosis stop progressing, coronary heart disease is much easier, and circulatory disorders in brain and diabetic angiopathy take on a milder form.
Composition and pharmacokinetics
The composition of Angiovit includes three beneficial substances:
- Vitamin B6, or pyridoxine hydrochloride, in an amount of 4 mg.
- Vitamin B9, or folic acid, in an amount of 5 mg.
- Vitamin B12, or cyanocobalamin, in an amount of 6 mg.
The pharmacokinetics of the drug is expressed in the rapid absorption of the beneficial substances that make up its composition.
Indications
Vitamin preparation "Angiovit" is indicated in the following cases:
- Prevention and treatment of diseases of the heart and blood vessels that are associated with a high level of the substance homocysteine ​​in the blood, namely: angina pectoris of the second or third degree; myocardial infarction; ischemic stroke; sclerotic abnormalities in cerebral circulation; diabetic vascular lesions.
- Circulatory disorders (fetoplacental), that is, blood circulation between the placenta and the fetus at earlier or later stages of pregnancy.
- Hyperhomocysteinemia.
Release form and dosage
The multivitamin preparation Angiovit is available in tablets, which are coated with a film coating. One package contains six sets of blister packs, ten pieces each.
According to the instructions, Angiovit is prescribed in a dosage of one tablet per day at any time of the day. You can take a vitamin preparation both during meals and after.
Course treatment is carried out for a period of three weeks to a month.
Side effects and contraindications
Vitamin preparation "Angiovit" side effects is extremely rare. Side effects can be expressed in various kinds of allergic reactions, for example, rash or other similar ones.
The main contraindications, according to reviews of Angiovit, are hypersensitivity to the main components of the vitamin complex. Despite this, it is recommended to take it under the supervision of a doctor, given the features of the main treatment.
Depending on what “Angiovit” is prescribed for, you need to know the compatibility of other drugs with the vitamin complex. With the joint appointment of "Angiovit" and antacids (for example, "Maalox" or "Almagel"), it should be remembered that the absorption of vitamins in this case is impaired. Therefore, the time interval between taking medications should be at least two hours.
Pregnancy and lactation
One of the first reasons why Angiowit is prescribed is pregnancy. A vitamin preparation can be recommended at any time when diagnosing a deficiency of vitamins from group B.
The lack of these elements provokes the occurrence of various congenital malformations and defects in the fetus, increases the risk of a lag in the already born child in mental or physical development. Also, a lack of folic acid, pyridoxine or cyanocobalamin leads to the appearance of anemia in the mother, which can subsequently lead to underdevelopment of the embryo or a decrease in the viability of the fetus.
Particularly dangerous is the deficiency of B vitamins for a pregnant woman with the risk of hyperhomocysteinemia, which can not only negatively affect the health of the mother and child, but also provoke the woman’s chronic inability to bear the child.
Drug interaction
The instructions for "AngioVIT" indicate the features of a combination of a vitamin preparation with other medicines and therapeutic agents. For example, the simultaneous administration of contraceptives (oral) and certain types of cytostatics reduces the effectiveness of the drug, and the simultaneous administration of diuretics enhances the effect of vitamins.
Folic acid reduces the therapeutic effect of Phenytoin, and taking analgesics for a long time, anticonvulsants (including Carbamazepine and Phenytoin), estrogens or oral contraceptives, on the contrary, negatively affects the body's absorption of folic acid. Antacids (including magnesium and aluminum preparations), Colestyramine and sulfonamides (including Sulfasalazine) also have a negative effect on acid.
The effect of the use of vitamin B9 is reduced from such drugs: Methotrexate, Pyrimethamine, Triamteren, Trimethoprim, which reduce the chemical reactions of dihydrofolate reductase in the body.
Pyridoxine hydrochloride has an enhancing effect on diuretics and a weakening effect on levodopa. In turn, the effect of vitamin B6 is weakened from isonicotine hydrazide, Penicillamine, Cycloserine, and estrogen-containing oral contraceptives.
Pyridoxine hydrochloride, which is part of Angiovit, is said to interact well with cardiac glycosides, increasing the synthesis of contracting proteins in the myocardium, and also using asparkam and glutamic acid increases the body's resistance to hypoxia.
With the simultaneous administration of cyanocobalamin with aminoglycosides, salicylates, antiepileptic drugs, colchicine or potassium preparations, the absorption of vitamin B12 is reduced. Cyanocobalamin does not combine well with thiamine, provoking the appearance of allergic reactions from vitamin B12. A combination of cyanocobalamin and drugs that increase blood coagulation can also negatively affect well-being.
Angiovit: analogues
The “Angiovit” vitamin preparation has no analogues in the structure of active substances, since the composition of the drug includes a rare combination of vitamins.
According to the pharmacological group, several preparations have a similar set of elements, therefore the following multivitamin complexes belong to the analogues of “Angiovit”:
- "Antioxycaps" with iodine;
- Alvitil;
- Beviplex;
- Aerovit;
- Vectrum Junior;
- Benfolipen;
- “Vetoron for children”;
- Vetoron;
- "Vibovit Junior";
- “Vibovit Baby”;
- "Vitamult";
- Vitabex
- "Vitasharm";
- "Vitacitrol";
- "Gendevit";
- "Hexavit";
- "Decamevite";
- "Heptavit";
- "Calcevita";
- "Jungle";
- "Makrovit";
- “Combilipen Tabs”;
- “Multivita plus;
- “Multi Tabs”;
- Neurogamma
- Neurotrat Forte;
- "Neuromultivitis";
- Pentovit
- "Pikovit forte";
- "Pikovit";
- "Multivitamin mixture";
- "Watering for children";
- "Revit";
- "Pregnavit F";
- Revitalize;
- "Sana Sol";
- "Rickavit";
- "Stressstabs 500";
- "Stress Formula 600";
- "Triovit Cardio";
- "Tetravit";
- Foliber;
- “Undevit”;
- "Unigamma."
Angiovit: reviews
There are practically no negative reviews regarding the Angiovit preparation, with the exception of stories about the combination of the vitamin complex with incompatible drugs.
In most cases, the course of the drug allows you to get rid of a deficiency of B vitamins in the body. This affects the general state of health and helps to alleviate the course of diseases caused by deficiency.
Vitamin complex "Angiowit", despite the small number of elements included in its composition, improves the well-being of the patient and alleviates the symptoms of already existing diseases.