Urinary incontinence, or urinary incontinence, is its involuntary flow, which is not controlled by volitional effort. This pathology is widespread among women, especially after forty years.
Urinary incontinence significantly worsens the quality of life, leads to the development of psychoemotional disorders, social, professional, domestic and family maladaptation. This pathological phenomenon is not an independent disease, but only a manifestation of other diseases of various origins.
Types of incontinence
In the treatment of all types of this ailment, medications are used. The greatest effect of treatment is observed in patients with urgent incontinence, arising from the urge to urinate. At the same time, a woman feels the need to urinate immediately and cannot postpone urination even for a short time. Medications for urinary incontinence in women are prescribed to increase the functional capacity of the bladder and reduce its contractile activity. Overflow incontinence is also known, which develops in older people suffering from diseases of the genitourinary organs, and is caused by overstretching of the bladder due to long-standing obstacles to the outflow of urine. With mixed incontinence, a combination of signs of stress and urgent forms of urinary incontinence is noted. Stress incontinence occurs in conditions that are accompanied by an increase in intra-abdominal pressure. In some cases, the pathology develops when exposed to external factors (acute cystitis, constipation, intoxication) and disappears after their elimination. Such incontinence is called temporary.
What medications are prescribed?
With urinary incontinence in women, antidepressants and antispasmodics are the drugs of choice. One of the most effective drugs used in the elimination of urinary incontinence is Oxybutin, which interrupts irritating irregular impulses from the nervous system and relaxes the detrusor.
Urinary incontinence with vaginal atrophy, physical stress without weakening the pelvic muscles is treated with a variety of drugs that have a decongestant and decongestant effect. Many experts believe that medications help get rid of this problem once and for all.
The list of the most famous and commonly prescribed drugs for urinary incontinence in women includes:
- "Detruzitol";
- Spazmeks
- "Urotol";
- "Driptal";
- Pantogam.
We consider them in more detail below.
Detrusitol
Instructions for use, price and reviews are of interest to many patients with incontinence. This medication belongs to the group of competitive blockers of M-cholinergic receptors. It reduces the tone of the smooth muscles of the urinary tract.
The active substance of this agent is tolterodine, a competitive antagonist of muscarinic cholinergic receptors, which shows the highest selectivity for the nerve endings of the bladder. In addition, the 5-hydroxymethyl derivative of the main component also has high specificity for muscarinic receptors and does not significantly affect other receptors. Thanks to treatment with tolterodine, the contractile activity of detrusor is reduced. The use of the drug in high doses can lead to an increase in the amount of residual urine and cause incomplete emptying of the bladder. According to reviews, the greatest effect of therapy is observed after 4 weeks from the start of treatment.
This medicine should be taken orally, without reference to food intake. The daily dosage of the drug is 4 mg. The drug is produced in capsules of prolonged action and in tablets. Depending on tolerance, the daily dose may be reduced to 2 mg. This is confirmed by the instructions for use with Detrusitol.
According to reviews, the price of this drug is quite reasonable. True, it is currently impossible to buy a medicine, since it is temporarily not available, so the cost of the drug is currently unknown. The pharmacy network offers analogues of this tool: "Urotol" and "Roliten." The first drug can be purchased for 520-670 rubles, the second - for 380-400 rubles.
Spazmeks
It is a drug for urinary incontinence in women with an antispasmodic effect, which helps to weaken the tone of the smooth muscles of the bladder. The active component of this agent, trospium chloride, is an M-anticholinergic, ammonium base, competitive antagonist of acetylcholine at the ends of postsynaptic membranes of smooth muscles. It has an affinity for M1 and M3 cholinergic receptors and is able to reduce the high activity of the bladder detrusor. In addition, this medication has a slight ganglioblocking and antispasmodic effect.
The instructions for use for Spazmex for urinary incontinence in women say that the medicine is taken orally 3 times a day, before meals, washed down with water. Usually it is prescribed at 30–45 mg per day.
The average price of a medicine (30 tablets per pack) depends on the dosage:
- 5 mg - 360 rubles .;
- 15 mg - 440 rubles;
- 30 mg - 680 rubles.
Below we also consider the preparation “Urotol”, instructions for use, price and reviews.
Medication "Urotol"
This medication belongs to the group of competitive blockers of M-cholinergic receptors. It reduces the tone of the smooth muscles of the urinary tract.
The active substance of this agent is tolterodine. The drug improves urodynamics. The active substance is a blocker of muscarinic receptors, and acts purposefully on the muscles of the bladder. Under the influence of the medication, the average volume of urine decreases, urinary incontinence is eliminated and the frequency of urges to urinate is reduced. Reviews of "Urotol" indicate good tolerance to this drug.
Instructions for admission
Urotol tablets are taken orally, 2 mg twice a day. Based on the tolerability of the drug, a single dosage can be reduced to 1 mg. At the same dose, the drug is prescribed for impaired renal and hepatic functions, as well as against the background of combined use with ketoconazole or other CYP3A4 inhibitors.
The approximate cost of the drug (56 pieces per pack) is 520-670 rubles.
Driptal
This is a medication for urinary incontinence in women, which has a direct antispasmodic, myotropic and M-anticholinergic effect, helps to relax the detrusor and reduces the frequency of its contractions, increasing the capacity of the bladder and restraining urination.
The main substance of this medicine is oxybutynin - a component that has an antispasmodic effect on smooth muscle structures and has an anticholinergic property, due to the ability to suppress the effect of acetylcholine on M-cholinergic receptors. In case of instability of the bladder, the drug increases its volume and reduces the frequency of sudden detrusor contractions.
“Driptan” for urinary incontinence is often prescribed. It is produced in tablet form, it is taken orally. Adults are prescribed 1 tablet 2-3 times a day. In childhood and old age - 0.5 tablets with the same frequency of administration.
The price of the drug is about 650 rubles. per pack of 30 tablets.
Pantogam
The drug "Pantogam" with urinary incontinence in women has an anticonvulsant and nootropic effect. The spectrum of activity that he exhibits is due to the presence of gamma-aminobutyric acid in its composition. The mechanism of influence on the body is due to the ability of this substance to exert a direct effect on the GABA receptor complex. The medicine has a nootropic and anticonvulsant effect, helps increase the brain's resistance to oxygen deficiency and the negative effects of toxic substances. In addition, this tool stimulates the anabolic processes that occur in neurons, reduces motor excitability, enhances mental and physical performance, demonstrates a combination of a mild stimulating effect with a sedative effect, and is widely used for urinary incontinence. The medication normalizes the metabolism of GABA in chronic intoxication, inhibits the pathologically high detrusor tone and cystic reflex.
How to use?
Pantogam medication should be taken orally 15-30 minutes after a meal, given its nootropic effect - in the afternoon or in the morning. In the form of tablets, the drug is prescribed for adults and children after three years.
The instructions for this drug indicate that the average dose for adults is 1.5-3 grams per day.
The price of the medicine (50 tablets per pack) is approximately 450 rubles.
Reviews
The reviews contain a wealth of information about effective pills for urinary incontinence in women. Such funds are also suitable for men, however, this pathology is most often diagnosed in the fair sex, which is due to the anatomical features.
Most of the good reviews left on the drug "Urotol". Patients note that this medicine quickly eliminates the above problem, does not contribute to the development of adverse reactions and is well tolerated.
“Driptal” is also a popular medicine, which, according to patients, successfully fights urinary incontinence, increases the time interval between urination and does not have a negative effect on the body.
There are both positive and negative reviews regarding the rest of the medicines reviewed, especially with the Detrusitol medication. Many patients are outraged that today this remedy is not on the shelves of pharmacies, although before the drug was often prescribed to eliminate urinary incontinence and was considered quite effective.