Fractional mesotherapy is a hardware technique for rejuvenating the skin of the face and body, involving the introduction of microinjections under the skin, which may consist of vitamins, drugs and minerals. During this process, microzones of the skin surface are pierced, which make up no more than 20% of the area of the treated problem area. A puncture is made by a variety of the thinnest needles with a beveled edge at a high pace to a shallow depth, which minimizes the morbidity of this procedure.
Principles of the methodology
Fractional microneedle mesotherapy forms microinjection zones with a width of about three hundred microns and a depth of 0.5 to four millimeters. The penetration depth depends on the type of damage being treated and is set by the attending physician as a parameter of a computer program, since penetration into wrinkles or post-acne craters, for example, is different, to obtain the optimal result. Fractional mesotherapy is used in the treatment of diseases such as:
- wide pores;
- scars from an acne rash;
- age-related gravitational ptosis in the neck, face or chin;
- pigmented disorders (melasma, sun spots, age-related);
- thin skin with a net of wrinkles;
- scars after surgical and other operations;
- striae (stretch marks) after a period of pregnancy, weight loss or hormonal changes;
- flabby skin of the eyelids, neck, décolleté, hands, etc.
Contraindications
Limitations for this fairly quick, effective, and painless procedure also exist. Fractional mesotherapy of a person whose reviews are mostly positive is not carried out if the patient underwent chemical peeling less than two weeks before therapy, has atopic dermatitis, is pregnant, suffers from epilepsy, herpes, or psoriasis. In addition, the procedure is not prescribed for inflammatory processes in the area that needs to be treated, and for colds accompanied by fever.
What causes skin regeneration?
Fractional mesotherapy of the face and other parts of the body, in addition to transporting nutrients deep into the skin, also has a microtraumatic effect on the tissues, which leads to their subsequent active regeneration. The exposure area of the apparatus is a separate treatment zone, around which are the so-called "mobilization zones" (healthier skin), of which stem cells will "go" to the problem area after the procedure, which are the body’s reserve that helps the skin recover from damage.

The processes in the skin that are caused by fractional microneedle mesotherapy are very interesting. After treatment of the site, aseptic inflammation occurs in it, during which damaged structures, as well as blood cells, collagen, melanin and elastin from the problem area are destroyed by macrophages. Fibroplasts are sent from the mobilization zone to the regeneration zone, which “repair” the basal layer in a day and form new collagen and elastin, from which a new cell framework is obtained. Such rates of recovery can reduce the rehabilitation period to several hours (you can apply cosmetics and shave the very next day), during which the skin actively absorbs the nutrients used to treat this or that process.
It will take several procedures
Fractional mesotherapy allows only one fifth of the problem area to be treated at a time, so it may take 4-5 procedures that are performed at intervals of 10-12 days to completely repair the damaged area. During this period, restoration processes are completed in the skin, and he is ready for the next treatment session. The apparatus of fractional microneedle mesotherapy, installed in a particular salon, may slightly differ from its “brothers” in its characteristics.
The main characteristics of devices for mesotherapy
For example, the Korean model “Dermopen EDR-02” has an adjustable needle length, from 0.2 to 2 millimeters, it includes cartridges with a dozen sterile needles that can penetrate the skin at an adjustable speed - up to 2400 punctures in one minute . The penetration density of the apparatus into the skin is quite high - 12 needles per 0.2 square centimeters, which allows the procedure to be performed with the least pain for the patient. The device makes it possible to process large surfaces at a high pace, giving customers the opportunity to process the skin on the body and face in one session.
Use not only for face and body
The more expensive fractional mesotherapy apparatus ZX 12-13, also available in Korea, has approximately the same characteristics as the Dermopen EDR-02. The ZX 12-13 device is distinguished by the lower cost of cartridges, which can be disinfected for several procedures for one client, while for Dermopen EDR-02 only one-time options are provided. The Z-X 12-13 device acts on the skin with 12 microneedles, which give a maximum adjustable speed of 3600 beats per minute, which allows it to be used in mesotherapy of the scalp and give increased effectiveness in the treatment of stretch marks. The penetration depth of the apparatus is still the same 0.2-2.0 mm. An additional advantage of the device is the possibility of its autonomous operation on the battery.
The apparatus of fractional mesotherapy "Raffin" is known among experts as a device with the thinnest needles having stylet sharpening. They penetrate the skin by only 0.3-0.8 mm, which allows procedures without local anesthesia, even on the face. The device is equipped with a fairly powerful Japanese motor and gives up to 2400 injections per minute, which allows not only to treat skin integument from scars and stretch marks, but also to get good results with cellulite, rosacea, atonic skin (enhanced nutrition), etc.
Does it hurt or not?
The most inexpensive are the salon procedures performed on the Mi-m device, which in itself is inexpensive. A feature of this device is the rather thick needles penetrating the tissue to a depth of 2 mm at a speed of 10 to 30 movements per second. The procedure can be quite painful, but the discomfort depends on the level of the patient’s own pain threshold. As a rule, fractional mesotherapy leaves no traces on the treated surface, but in some cases small swelling is possible, which, however, quickly disappears.
The result is not always guaranteed.
When visiting a client’s salon, as a rule, they do not pay attention to which fractional mesotherapy apparatus is used. Reviews expressed later are sometimes negative, as the girls do not get the desired result. This is possible in the case when an unscrupulous cosmetologist, using the apparatus, for example, did not take into account that the pits from the post-acne can be much deeper than the needles of the apparatus. But in general, the impressions of this procedure in women are more than positive, since the skin becomes fresh, toned, elastic without surgical intervention.
Mesotherapy at home
Can fractional mesotherapy be carried out at home? Reviews of mesoscooters - mechanical devices for personal use - indicate that such operations are possible, but they are less effective compared to salon procedures. When using a mesoscooter, you need to remember that it should be disinfected after application with hydrogen peroxide, medical alcohol or special liquids and sprays, do not treat with steam or other high-temperature methods (autoclave, etc.), do not drop, as this can damage the thinnest needles, which further lead to injuries of the treated skin.
Ah, this “magic” hyaluronic acid!
Preparations for fractional mesotherapy, used in salons and at home, are most often based on hyaluronic acid. It is a synthetic substance of non-animal origin, which, when introduced, promotes the formation of a protective film that resists the effects of the environment, which determines the moisture level of the skin, gives the skin elasticity, smoothes wrinkles, and helps heal wounds without scarring. The maximum concentration of natural hyaluronic acid in the body occurs in young years (up to 25 years) due to its natural synthesis. Therefore, young people have such beautiful and fresh faces.
Consumers report that after applying hyaluronic acid-based mesococtails, skin color improvements and tightness can be seen almost immediately, which can last up to several months, after which the procedure must be repeated. For a more long-term effect, mesotherapy should be carried out in several courses, which is considered by many ladies to be quite expensive (one procedure on the face can cost from 2500 rubles). But it should be borne in mind that, in addition to everything else, the work of a cosmetologist is laid in the price of the service, the result of skin manipulations almost always depends on its qualifications. For example, not many people know that the same hyaluronic acid preparations cannot be applied with home scooters directly to the inner corners of the eyes so as not to harm the lacrimal glands.

Hyaluronic acid-based preparations, such as NCTF, offered in salons and stores, also contain vitamins (C, E, A), mineral-salt complexes that help absorb scars, and others. To smooth wrinkles, complexes with peptide argyregin that relax muscles are offered. . Mesotherapy lotions used to treat allopecia contain plankton extracts, and gels for eliminating acne eruptions contain active sulfur compounds. With the help of fractional mesotherapy devices, you can also get rid of dark circles under the eyes, if you use a solution of hyaluronic acid in combination with vitamins and troxerutin. Only a highly qualified specialist can choose the right drug and carry out all the necessary manipulations with it.
Get rid of the "stars" and dark circles
In addition, fractional mesotherapy, reviews of which are more often positive than negative, allows you to get rid of puffiness (solutions with artichoke), spider veins (medications based on ginkgo biloba), increase tone (mesococtails, including meliloto and rutin), reduce size “Breeches” or “second chin” due to the use of concentrates with L-picture or lipolytic caffeine.
The above drugs are often diluted to the desired concentration with a bioactivator (two percent procaine), which reduces the concentration of nutrients to the required and reduces the pain from the rejuvenation procedure performed at home or in the salon. In addition, users often buy special disinfectants if they use their own individual mesoscooters, which are subject to thorough sterilization before each procedure.
The average estimate for the mesotherapy procedure obtained from surveys of Russian ladies is about 4 out of five possible. There are completely negative (skin condition has not changed, the manipulations are painful, the cost is high), and enthusiastic reviews about rejuvenation for ten years, painlessness and affordability of high prices for such a wonderful operation.