The drug "Preductal MV" is a tablet that is coated with a special shell. The composition of these tablets includes trimetazidine dihydrochloride, the content of which in one tablet is thirty-five milligrams.
This is a drug of antianginal pharmacological action. It is able to normalize the process of energy metabolism of cells that were susceptible to phenomena such as hypoxia and ischemia. In addition, Preductal MV helps to avoid lower levels of intracellular ATP. That is, this medication acts in such a way as to ensure the correct, normal operation of the membrane channels, the transfer of sodium ions with potassium through the membrane. It also contributes to the conservation of cellular homeostasis.
The substance trimetazidine slows down the oxidation of fatty xylots. This is due to the selective inhibition of 3-ketoacetyl-CoA thiolase. Due to this process, there is an increase in glucose oxidation, the conjugation of glycolysis and oxidative decarboxylation is restored. Thus, protection against dangerous diseases such as ischemia and myocardial infarction is provided.
Laboratory experiments were performed on animals, the results of which showed that the substance trimetazidine supports cardiac metabolism during ischemic episodes, as well as the metabolism of neurosensory organs. The drug "Preductal MV" is able to lower the acidosis content in cells, to reduce changes in transmembrane ion fluxes that occur in a person with ischemia.
Clinical studies have shown that people with heart disease, including angina pectoris, felt an increase in coronary reserve. It was due to him that the development of ischemic disease slowed down , which was caused by excessive physical exertion. Such a slowdown occurred already on the fifteenth day of therapy. The use of the drug caused a limitation of sharp jumps in blood pressure without significant changes in heart rate. The drug "Preductal MV" helps to reduce the frequency of angina attacks, significantly reduces the patient's need to take nitroglycerin, improves the function of the contraction of the left heart ventricle in those people who suffer from coronary artery disease.
Preductal tablets are prescribed for long-term therapy of coronary heart disease, for prophylactic purposes, to avoid angina pectoris, for the treatment of vestibular disorders that are ischemic in nature (for example, dizziness, hearing loss, tinnitus). Also, "Preductal MV" should be taken for chorioretinal vascular disorders that contain an ischemic component.
It is extremely important to know how to take this medicine correctly. Qualified specialists always prescribe a certain pill intake rate. So, as usual, the drug is taken one tablet twice a day. The tablet should be taken during the meal - at breakfast and at dinner. Doctors set the course of treatment individually.
A drug may have some side effects. It is extremely rare, but side effects such as nausea and vomiting occur. There may be an allergic reaction to tablets. Do not use this medicine for people who have hypersensitivity to the drug. Do not use it for pregnant women, since clinical studies of its effects on expectant mothers have not been conducted. In addition, trimetazidine can be excreted in a woman along with breast milk. Therefore, it is better not to breast-feed a baby.
The analogue of Preductal is the Rimecor drug.