Any illness can occur with each of us, but most often we have to deal with viral respiratory diseases. We are sick of them at any time of the year, even in summer. At first glance, the common cold and the accompanying runny nose do not cause concern. However, with improper or inadequate treatment, they can turn into serious problems. Domestic drug Derinat for inhalation is able to quickly and effectively fight against viruses that attack the upper respiratory tract, thereby saving a person from local manifestations of the disease. At the same time, the immunomodulating properties of the drug contribute to the strengthening of the body's defenses, which gives the right to use it as a prophylactic. This article provides detailed information about the drug, as well as its advantages and disadvantages.
general description
Derinat for inhalation is a clear liquid substance with almost no smell. The drug is available in two forms:
- For external use, a solution with a concentration of the main component of 0.25%. You can buy glass bottles of 10 ml and 20 ml, as well as bottles with nozzles dropper or spray.
- For injection, an intramuscular solution with a concentration of the main therapeutic component of 1.5%. Available in glass bottles, as well as in ampoules of 2 ml (10 pieces in a pallet in one pack) or 5 ml (5 pieces in a pallet in one pack).
Chemical composition:
- sodium deoxyribonucleate (the main component in this medicine);
- sodium chloride (excipient);
- water for injection.
The instruction reports that it is possible to store a closed preparation in room conditions, at temperatures not lower than +4 degrees and not higher than +20 degrees. Shelf life is always indicated on the packaging and is 5 years, but this applies only to the unopened bottle. After opening, the product must be used within 2 weeks. It must be stored in the refrigerator.
Healing properties
Derinat is a new generation drug. For external use (in the form of drops) during the treatment of inflammation of the sinuses, as well as the eyes, it activates the local immunity of the mucous membranes, restores the regeneration of damaged cells and tissues. When taken internally (as an injection), it optimizes the body's defenses against various infections (viral, fungal, bacterial). The main component of the drug, sodium deoxyribonucleate, once in the body, quickly integrates into cellular structures and begins to positively affect the course of cellular metabolism. In the practice of treating children, it is especially convenient to use Derinat for inhalation. During this procedure, the drug penetrates directly into the area of inflammation, where it is rapidly absorbed by the cells and distributed in the affected tissues. In the body, Derinat is metabolized and excreted mainly with urine, and partially with feces. The elimination period is up to three days, during which the drug actively "works" in the cells of the body.
An important advantage noted in the instructions for this medication is that it does not have a teratogenic effect (does not cause fetal malformations in pregnant women) and is not a carcinogen.
Application area
Derinat can treat a very wide range of diseases, including skin injuries (burns, cuts, frostbite), inflammation of the genitourinary system, and hemorrhoids. Derinat for inhalation is mainly used for infection with viruses of the upper respiratory tract and bronchial asthma. With the help of this therapeutic technique, it is possible to significantly ease the course and accelerate recovery in the following diseases:
- rhinitis;
- sinusitis;
- laryngitis;
- sinusitis;
- tracheitis;
- bronchitis;
- adenoiditis;
- tonsillitis;
- pneumonia;
- ARI;
- ARVI.
Principle of use
As practice has shown, for the treatment of children it is most convenient to use "Derinat" for inhalation with a nebulizer. During normal inhalation, vapors are produced that the patient breathes, and the nebulizer produces an aerosol from small particles of the drug, which have a therapeutic effect on the mucous membrane of the sinuses or throat, and are also able to reach the pulmonary alveoli. In addition, the use of a nebulizer for inhalation with Derinat practically eliminates the side effects of treatment, therefore it is suitable even for infants. It is possible to treat a child using a nebulizer for inhalation both when the baby is awake and when he sleeps. To do this, use the mask that came with the device. With its help, almost all the medicine will fall into the respiratory tract of the child, and not fly around the room. To use the classic apparatus for treatment, the inhaler can be used by children after they reach the age of 3 years.
Dosage
Pediatricians often prescribe Derinat nasal drops for children with signs of acute respiratory viral infections. For inhalation, the instructions do not tell how to use this drug. There are no such indications in the instructions attached to Derinat for injection. Therefore, many parents do not know what they should buy to make the child inhalation, and how to prepare the solution. In principle, the drug is suitable in any form of release, the main thing is to correctly observe the dose. If you use a solution of 0.25% (for external use), you need to take 1 ml of Derinat and the same amount of saline with a syringe. If you use a solution of 1.5% (for injection), you need to take 1 ml of the drug and 3 ml of saline.
In both cases, the duration of the procedure is only 5 minutes. You need to do them twice a day, the course of treatment is 5 to 10 days.
Adverse reactions
According to the manufacturer, no side effects are observed with the local use of Derinat. Inhalation with a nebulizer for children is considered the most gentle and safe method of treatment. However, in babies with individual intolerance to the components of this drug, an allergic reaction may occur, manifested by a rash. It quickly spreads over the body of the child and causes itching, anxiety, moodiness. Intolerance to Derinat components is extremely rare, but the pediatrician prescribing this medicine must make sure that it is suitable for a small patient. In adults, with external use of the drug, complications and side effects are not observed. It is important to note that while rigorous studies of the effect of sodium deoxyribonucleate on fetal development of the fetus have not been conducted. Therefore, despite the manufacturers' statement that Derinat has no teratogenic effect, pregnant women can use it only after consulting a doctor.
Errors during the procedure
In order to avoid unpleasant consequences after inhalation with Derinat, the dosage of the solution prescribed by the attending physician must be observed exactly. What can not be done when preparing a solution for inhalation:
- Independently increase the dose of the medicine, as this will not only not lead to a speedy recovery, but will also cause an unfavorable response from the body.
- Reduce the prescribed dose. This will not cause negative reactions, but also the therapeutic effect will significantly reduce.
- Replace saline with plain water. This can trigger bronchospasm.
- Use medicinal oils in conjunction with Derinat.
- Carry inhalations more than twice a day or increase the duration of procedures.
Which is better, inhalations or drops
According to doctors, the best treatment for colds, coughs and other manifestations of acute respiratory viral infections is inhalation with Derinat. For children, this process can be somewhat difficult, especially if the procedure is performed with a classic inhaler. A mouthpiece is included in the kit, which children should take in their mouths when vapors with medicine are released from it. The nebulizer partially facilitates the task, since the kit does not contain a mouthpiece, but a mask, which during the procedure must be put on the child’s mouth and nose. Children tolerate this procedure much easier. In addition, nebulizers for the smallest are produced in the form of cars, trains and other toys, which takes the child and allows him to complete the procedure. Whoever doesn’t have an inhalation apparatus at home can use the medicine “Derinat” drops. Inhalations are more advantageous in that they are carried out only twice a day with a course of no more than 10 days. Nasal instillation is more convenient because the process takes only a couple of seconds. According to the reviews of adult patients and parents of babies, drops “Derinat” perfectly cope with a runny nose, as well as inflammation of the eyes and ears. However, in some babies, they provoke local reactions in the form of bloody discharge from the nose. Another disadvantage of using drops is that you need to carry out a similar procedure many times a day, and the duration of treatment is a month.
Interactions with Other Medicines
Doing inhalation with Derinatom as a complex therapy is allowed in conjunction with the use of antiviral drugs and antibiotics. This immunomodulatory drug increases their effectiveness, accelerates recovery and reduces the course of taking other medicines. For external use, Derinat cannot be combined with hydrogen peroxide and with ointments made on a fat basis. When performing inhalations, you cannot add to the Derinat solution any other means used for a cold or cough.
Prices where to buy
The ready-made Derinat solution for inhalation is not sold with a nebulizer or simple inhaler. You need to cook it yourself. In pharmacies without a prescription, you can buy Derinat medication for external use or nasal drops. Now on sale this drug for babies. The solution in ampoules for injection is a prescription. Average prices:
- for nasal drops with a pipette nozzle - from 330 rubles;
- for spray with a nozzle sprayer - from 420 rubles;
- for a solution in glass bottles with a volume of 10 ml - from 270 rubles;
- for ampoules for intramuscular injection (package of 5 pieces) - from 2000 rubles.
Opinions of foreign pharmacists
Russian pediatricians often use inhalation with Derinat to treat viral infections of the respiratory tract in children. Reviews about the use of such a therapeutic method are mostly favorable. There are other drugs on the pharmaceutical market with similar properties. Among them is "Deoxinat", which is also an immunomodulator. Its chemical composition:
- sodium deoxyribonucleate;
- sodium chloride;
- water for injection.
Other analogues are “Panagen” and “Sodium Deoxyribonucleate”. The use of these drugs for inhalation is not yet practiced, but they are used for intramuscular administration and topically. However, sodium deoxyribonucleate and preparations based on it are not included in the guidelines for the treatment of patients abroad. These drugs are not on the WHO list and on the list of medicines for the treatment of acute respiratory viral infections compiled by the Russian Ministry of Health. Meta-analyzes and a systematic review of the use of these tools are also missing.
Reviews
In Russia, according to patient reviews, Derinat has been used quite successfully. The solution for inhalation does not cause difficulties in preparation, and the method of treatment of the common cold and other manifestations of acute respiratory viral infections is simple and effective. Many patients report in their reviews that, thanks to Derinat, they manage to get rid of sinusitis and rhinitis in a matter of days. A good prophylactic effect of this drug is also noted.
The disadvantages of using Derinat for inhalation are not reported.
In general, such disadvantages of the drug are called:
- high price, especially for ampoules for injection;
- short shelf life after opening the bottle;
- the need to store an opened drug in the refrigerator, which requires heating before use;
- not all patients have a quick effect from the use of the drug.