Today, endometriosis is a serious gynecological problem. Every third woman with a diagnosis of infertility is diagnosed with this disease. Recently, the drug Janine has been actively used to treat endometriosis.
A serious task is to prepare a woman with this problem for pregnancy, since for her successful onset and course it is necessary to stop the progression of endometriosis. Recently, successes have been made in this direction.
Endometriosis is treated surgically and medically. Each has indications, shortcomings and advantages. The decision is made by the doctor, taking into account the condition of the patient, the stage of the disease and the localization of the process.
Recently, combined contraceptives (COCs) are increasingly being included in treatment regimens for this disease, along with strong medications . Modern drugs are highly effective, especially in the prevention of recurrence of endometriosis.
They have less pronounced adverse reactions, they do not affect metabolic processes and do not cause the absence of menstruation. Therefore, the use of COCs is especially important for the treatment of young patients.
Janine and endometriosis - today is a particularly interesting combination for doctors and patients. It includes dienogest - the first progestogen, causing almost complete regression of endometrioid heterotopia.
The drug is highly bioavailable, therefore, small doses are enough to ensure a clinical effect. The combination with estradiol provides a normal menstrual cycle for a woman.
The patient begins taking the drug Janine, and endometriosis disappears or there is a partial remission. This effect is achieved in 85% of cases according to the results of endoscopy, especially if the form of the disease is not severe.
A woman is undergoing treatment with Janine, and endometriosis of the uterus becomes less pronounced according to ultrasound. In this case, no significant changes in weight, liver function, blood pressure are detected.
Recently, there has been a review of the regimen of contraceptive use. Today, prolonged use regimens are actively used. In accordance with them, the drug is continuously used for more than 60 and even 80 days.
Such schemes are especially promising for preparing women with endometriosis for pregnancy. Already today, such a reception by Janine gives positive results.
However, while it is used according to the contraceptive scheme. Reception Zhanina 21 days, and then a break of 7 days. The duration of the course is from six months to a year.
Only in this way can scarring of the endometrioid ectopia occur. After a course of therapy, the probability of pregnancy significantly increases.
Three months after the start of administration, it is necessary to monitor the function of the liver and blood. To do this, make a hemostasiogram and blood biochemistry. The drug Janine, the analogues of which Dienogest + Ethinyl estradiol, can be taken only under the supervision of a doctor.
However, the main indication for taking the drug is pregnancy protection. It suppresses ovulation and changes the viscosity of cervical mucus. At the same time, sperm can not pass through it.
During the application of Janine, the cycle is usually more regular, the soreness, duration and intensity of menstruation decreases. Therefore, the risk of anemia is reduced. There is evidence of a decrease in the likelihood of ovarian cancer when taking the drug.
Thus, it has already been established that the patient is undergoing treatment with Janine and endometriosis either disappears with a mild form of the disease, or partial remission is observed in 85% of cases. The role of this drug is especially important in preparing young patients for pregnancy. Recently, it is increasingly being used according to a prolonged scheme.