In the article, we consider what it means when the average hemoglobin content in an erythrocyte is increased.
The average content of an element such as hemoglobin in an erythrocyte in the assays is designated as “MCHC”. This indicator reports how strongly red blood cells are saturated with this protein. In other words, we are talking about the ratio of hemoglobin to cell volume. It is calculated according to a specific formula in which hematocrit is taken into account along with the level of iron-containing protein. The hemoglobin content in the red blood cell does not depend on the volume of the cells and does not reflect the absolute level of iron-containing proteins in the red blood cell. Measure this analysis in grams per liter. And, in addition, it is measured in grams per deciliter.
Erythrocyte indices
In addition, you should know the difference between the erythrocyte index "MCHC" and "MCH". The latter indicator reflects the average concentration of hemoglobin in red blood cells. It shows the amount of iron-containing protein in each red cell and is measured in fractions of a gram. The “MCHC” indicator does not reflect the amount of hemoglobin, but directly the density of filling of red blood cells with it. "MCH" stands for the specificity of the formation of iron-containing protein.
Red blood cells - what is it?
Red blood cells represent the largest variety of human blood cells. Their main function is the process of transfer of oxygen and carbon monoxide. In addition, these red blood cells take part in the transport of nutrients and the immune response, helping to maintain acid and alkaline balance.
Not everyone knows that these are red blood cells.
How is it determined?
In order to determine the average concentration of hemoglobin in red blood cells, a general analysis is prescribed. Blood is donated in the morning to an empty stomach. Doctors make a fence from the finger within the laboratory. It is forbidden to eat, drink alcohol and other drinks, except water, at least eight hours before taking the test. Results are obtained through a hematology analyzer.
Norm "MCHC"
The normal rate, on average, is in the range of 300 to 379 grams per liter. It may differ depending on age, and, in addition, from gender.
What should be the norm of hemoglobin in red blood cells in adults is interesting to many.
For men, a normal indicator is considered a value from 320 to 364 grams per liter, and for women from 320 to 354. Norms for children are usually as follows:
- Under the age of four, from 279 to 379.
- Five to fourteen from 320 to 365.
What is it used for?
The average concentration of HB in red blood cells is one of the most constant values in a blood test. Against this background, it is used to detect errors during laboratory testing. Doctors use the MCHC Index in the following cases:
- As part of evaluating the effectiveness of the treatment of anemia.
- In the process of differential diagnosis of anemia.
- Against the background of the diagnosis of hypochromia.
Iron deficiency anemia is a common pathology in our time. It is explained by insufficient intake of iron with food or its difficult digestion in the digestive system, and may also be interconnected with some chronic pathologies and blood loss. This deviation is characterized by a reduced level of red blood cells that occurs due to severe bleeding, against the background of increased destruction of red blood cells or impaired formation of blood cells. In everyday life, anemia is called anemia. For its diagnosis, usually only one analysis to establish the level of hemoglobin and red blood cells is not enough. Typically, the following parameters are examined, which together provide a more complete picture:
- Analyze the average concentration in the red cells of hemoglobin.
- The average hemoglobin content in one erythrocyte is investigated.
- Doctors analyze the width of the distribution of red blood cells directly in volume.
- The average volume of red blood cells is examined.
- Color indicators are being studied.
Why can the average hemoglobin content in an erythrocyte be increased?
MCHC promoted: reasons
The concentration of hemoglobin in the red blood cell may increase in a number of the following cases:
- Against the background of hyperchromic anemia with ovalocytosis, spherocytosis, and so on.
- If there is a violation of water and electrolyte metabolism.
- This indicator can increase in newborns, which is considered the norm.
An increased value of the content of iron-containing protein is quite rare. In the event that the MCHC rises to a value of 380 grams per liter, continuing to grow, hemoglobin crystallization may occur.
Often, when the average hemoglobin content in an erythrocyte is increased, this is not associated with any disease, but indicates an error in a laboratory study, since high concentrations lead to a morphological change in red cells and their absolute destruction. There is only one disease in which this indicator is increased. It is a hereditary pathology, namely spherocytosis. This condition is referred to as hemolytic anemia, it is characterized, as a rule, by a defect in the cell membranes of red bodies. In most situations, based on the fact that the average hemoglobin content in the red blood cell is increased, the following technical errors are present:
- Incorrect determination of hemoglobin and hematocrit including.
- Violation of the conditions for blood sampling along with its storage, in connection with which there is a partial breakdown of red blood cells.
Treatment
To date, doctors say that an increase in the considered indicator of more than thirty-eight percent practically does not occur. In the event that the analysis showed such a serious increase, then most likely the equipment used to perform the blood test failed. But, in the event that all blood counts are deviated from the norms, then it is worth looking for the causes of the discrepancies.
Doctors consider pathological significance when the increased average hemoglobin content in the erythrocyte MCH is more than thirty-six percent. In this analysis, the causes of deviations should be identified. In the event that the cause is a specific disease, it should be urgently treated. If you follow all the recommendations of doctors, you can balance the amount of hemoglobin, and, in addition, restore your health.
Decryption analysis
After the patient receives the "MCHM" analysis, it is required to go to his doctor with these results. Only a specialist will be able to correctly decrypt all values and prescribe treatment. Many people make the same mistake every day; they try to decipher their analyzes on their own. In addition, having set themselves the wrong terrible diagnosis, people in addition begin to intensively treat non-existent pathology, thereby causing irreparable harm to themselves.
Such patients often find themselves in an emergency hospital, because the uncontrolled use of drugs and alternative treatment methods can provoke various malfunctions in the body. A study on the amount of hemoglobin in red blood cells is carried out in absolutely any clinic, after which the results of the study should be analyzed by a doctor. Do not self-medicate, as this is the right way to a serious and long-term illness.
Thus, the value of “MCHC” in medicine is never considered separately from other indicators. Typically, blood is examined by many parameters and by several erythrocyte indices at once, including: “RDW”, “MCH” and “MCV”. Only all the values in the aggregate allow us to judge the violation in the body and the occurrence of certain pathologies. The “MCH” and “MCHC” indices are of fundamental importance in diagnostics, since with their help it is possible to obtain the most complete information about hemoglobin.
Prevention
Long-term studies show that most patients who have a high average concentration of HB in red blood cells have bad habits. The main boosting factor is smoking. It is this habit that can cause chronic oxygen starvation of the body, while destroying blood cells. Dangerous resins can envelop the lungs and interfere with oxygen absorption, and the poison contained in cigarettes simply kills the body's cells and red blood cells, including.
In the event that a person wants to live a healthy life, then he needs to give up smoking, and, in addition, from drinking alcohol. Of course, people hear such truths everywhere, and it is for these reasons that many cease to perceive them as a guide to action. Awareness for people, unfortunately, comes late, when the body already gives a certain malfunction and at this stage doctors can’t do anything.
We examined in which cases the average concentration of hemoglobin in the red blood cell is increased. The reasons for this should be determined by the doctor.