Dioxidin is an antibacterial drug from the group of quinoxaline derivatives, has a wide spectrum of action and chemotherapeutic activity in many infections. Dioxidine in the ampoule is active against many pathogenic and non-pathogenic microbes: Klebsiella, Pseudomonas aeruginosa, Salmonella, pathogenic anaerobes (including causative agents of gas gangrene), dysentery sticks, staphylococci and streptococci. The drug affects strains of many bacteria that are resistant to other antibiotics and chemotherapeutic agents.
The effect of the drug Dioxidin
Irrational use of the drug can lead to the development of bacterial drug resistance, which is why when using dioxidine in an ampoule, the dose recommended by the doctor must be observed. The drug is used to treat purulent-necrotic and burn wounds, as a result of which the surface is quickly cleaned, regeneration and epithelization of damaged areas occurs. Often, the drug is used to treat chronic sluggish infections that are difficult to treat. For external use, dioxidine is partially absorbed and excreted in the urine.
Dioxidine in an ampoule: indications for use
The drug is often used externally for purulent bacterial infections, for trophic ulcers and long-term healing wounds, as well as for infected burns, phlegmon and osteomyelitis. With purulent otitis media, dioxidine drops in the ear are quite effective , it is also sometimes used with advanced purulent sinusitis. In some cases, Dioxidin is used for inhalation, and is also injected into the cavity during purulent processes in various organs, with lung abscesses and pleurisy, and in wounds with deep cavities. With periodontal disease, mouthwash with dioxidine is permissible, however, this is done very carefully, avoiding ingestion of the drug inside.
Dioxidine in the ampoule: contraindications
Contraindications to the use of the drug are individual intolerance, pregnancy and lactation, adrenal insufficiency, children's age up to seven years, in some cases, renal failure. When treating with dioxidine, one should take into account the patient's state of health, his medical history. If the patient has chronic diseases or has an unfavorable heredity, the doctor should evaluate all the risks associated with the use of the drug and compare them with the expected effect.
Dosage and administration of dioxidine
For intravenous administration, you cannot use a 1% solution of dioxidine, since it has the property of crystallizing at low temperatures. Outwardly use 0.1-0.5 –1% Dioxidine solutions. In the treatment of purulent and burn wounds, wipes soaked in a sterile solution are used. For deep wounds, tampons are used, also soaked in a solution of the desired concentration of Dioxidine, and if there is drainage, the drug is injected into the cavity (up to 100 ml). Sometimes, baths with dioxidine are used to treat purulent wounds, in particular, they are used for osteomyelitis of the hands and feet, followed by sterile dressings with the drug.
Dioxidine in ampoules is a great anti-inflammatory drug that is simply necessary for the treatment of certain diseases. However, with all the advantages of the drug, in large doses, it becomes a poison for the body, capable of destroying living active cells. That is why it is not recommended to use dioxidine in ampoules without the appropriate doctor's prescription, to violate its prescriptions and dosages. Local use of the drug is also unacceptable without consulting a doctor, as well as intracavitary.