Health is a gift, it cannot be bought or ordered, but each of us has the opportunity to support it with the help of special means. In medicine, they are called drugs. They can be presented in different forms of release, but very often we use tablets to treat any pathologies in the body.
What is the Mikardis medicine for?
Each medical product has its purpose. There are very few broad-based facilities. After all, human systems and organs are arranged in different ways, and completely different microorganisms act on them. For the treatment of many pathological processes, certain drugs have been developed.
The drug "Mikardis" is actively used to treat arterial hypertension, a disease in which blood pressure rises. In addition, the Mikardis drug, whose analogues also prevent an increase in blood pressure, is an excellent prophylactic drug that reduces the risk of diseases of the cardiovascular system and prevents the death of patients older than 55 years.
How does the drug work at a physiological level?
The drug "Mikardis" is an angiotensin II receptor blocker. Its pharmacological effect is to lower the level of aldosterone in the body. The drug does not block ion channels and does not slow down the effects of renin and kininase II (an enzyme that can destroy bradykinin). The drug "Mikardis" (Russian analogues sometimes differ slightly in composition) contains telmisartan. This is a biologically active substance that has a therapeutic effect on the body.
In simple terms, the effect of the drug is as follows: "Mikardis", its analogues can normalize systolic and diastolic blood pressure, improve the condition with bradycardia and tachycardia. The drug lowers blood pressure without affecting the heart rate, so this therapy is suitable for many patients.
With a sharp cessation of taking the drug, the pressure level returns to baseline. This does not cause the patient to develop withdrawal syndrome. Another indicator, a symptom of high blood pressure and heart disease is a cough. This is a dry, so-called "cardiac" cough. During the use of "Mikardis" this symptom does not appear as often as before telmisartan therapy.
Once inside, the drug is absorbed in the digestive organs up to 50%. In this case, 99.5% is bound by blood proteins. The first effect after taking the drug occurs after 3 hours and lasts 24 hours. In rare cases, the hypotensive effect lasts up to 2 days (or 48 hours). With regular admission, the therapeutic effect is achieved for 4-8 weeks.
If the patient is diagnosed with impaired renal function, it is necessary to periodically monitor the levels of creatine and potassium in the blood serum. It is also necessary to exclude violations of the water-electrolyte ratio in the patient's body before prescribing the drug. Also, with caution, you should take "Mikardis" if there are deviations in the work of the biliary tract. After all, the substance telmisartan is excreted mainly with bile.
The timing of the removal of the drug from the body
The time of excretion of "Mikardis" from the body is about 20 hours. The main part of the drug is excreted together with feces in the form in which it entered the digestive system. About 1-2% of telmisartan is excreted through the kidneys. Plasma clearance is kept at a fairly high level. Its level is 900 ml / min in comparison with the blood flow of the liver, which is kept at 15,000 ml / min.
Patients taking "Mikardis" analogues of the drug should remember that telmisartan is not excreted using the hemodialysis procedure. The timing of drug withdrawal does not depend on the age of the patient. The drug is excreted with equal speed from both the male and female bodies.
Indications for use of a medical product
The instructions for use will help you to navigate the rules of taking the drug "Mikardis" . Reviews, analogues of the drug will be considered below. The main indications for the course of treatment with the drug are cardiovascular disorders of the body. He copes well with the treatment of tachycardia, bradycardia, arterial hypertension, that is, blood pressure disorders, which include primarily hypertension.
An excellent prophylactic indicated for use by people over 55 is Mikardis Plus. Drug analogs are also used to reduce the likelihood of developing the most dangerous diseases of the cardiovascular system, which occupy a leading place in mortality.
Dosage of medication
The drug is taken orally. The intake time does not depend on the meal regimen. To reduce high blood pressure, you should start taking one tablet (40 mg) once a day. With an insufficiently pronounced therapeutic effect, the dose should be increased to 80 mg per day. Some patients have enough 20 mg per day, but in this case, it is sometimes necessary to take a control measurement of blood pressure so as not to miss high values. Before taking the drug for educational purposes, you must first study the complete information on the drug "Mikardis". Instructions for use (drug analogues used in some cases have a similar effect) will help you see the whole picture of the treatment of the disease.
The average dosage for the prevention of cardiovascular disease is 80 mg / day. In some cases, at the beginning of treatment, additional medications that normalize blood pressure will be required. The dose of taking the drug is determined by the doctor after studies of the state of the body. The first time after the appointment of "Mikardis" you need to measure the pressure in the morning and evening. This is done in order to determine the body's response to the drug and its effectiveness. It should be noted that in most cases, dose adjustment is not required, but patients who have impaired liver function should not be prescribed a dose above 40 mg. The duration of treatment with this drug is determined individually. The doctor evaluates the effectiveness of the prescribed treatment and the nature of the pathological process in the patient’s body.
In medical practice, no cases of overdose have been identified, but theoretically it can manifest itself in such conditions of the body as tachycardia, low blood pressure, bradycardia.
Who should not use the drug?
With caution and following all the prescriptions of doctors, you should take "Mikardis" (analogues, synonyms, generics) for people with liver and biliary tract diseases. Patients with individual fructose intolerance (since the drug contains a large amount of sorbitol), sucrose deficiency, impaired galactose and glucose metabolism are referred to the category which the drug is categorically contraindicated. Children under the age of 18 are strictly contraindicated in taking Mikardis, and its effect on the children's body has not been studied today.
The drug should be taken with great care when:
- recovery after kidney transplantation;
- hyperkalemia;
- stenosis of the mitral and arterial valve;
- liver diseases;
- pyelonephritis;
- hyponatremia;
- bilateral renal artery stenosis;
- chronic heart failure.
Use of the drug during pregnancy and lactation
The drug is forbidden to be taken by women during pregnancy and during lactation (breastfeeding), since this can negatively affect the general condition of the child and mother. During pregnancy planning, you need to replace the Mikardis medical product, its analogues (but not all) will more effectively affect the health of the expectant mother.
If it turns out that you have become pregnant while taking the drug, you should immediately stop taking it and tell your doctor what medicines you were taking at the time of pregnancy. This is due to the fact that when using the drug, its fetotoxicity may appear (impaired renal function, slow ossification of the child’s skull, hypotension, hyperkalemia).
In what forms is Mikardis produced?
This medication is presented in oblong white tablets that should be taken orally. The designation “51H” stands on the tablets. There are two types of dosage: 80 mg and 40 mg tablets. The package contains 2 - 4 blisters of 7 tablets (14 or 28 pieces).
What are the analogues of the drug?
If you are interested in the drug "Mikardis", analogues, price of the medicine, we recommend that you find out information in the pharmacies of your city. After all, the pricing policy for each network of pharmacies is different, so the prices of the drug and its substitutes can vary significantly. Synonyms of the drug are "Prirator", "Mikardis Plus."
Analogues of the last drug are enhanced drugs that act on the cardiovascular system. These include Gizaar Forte, Atakand Plus, Valzap Plus, Teveten Plus, Co-Diovan and some others. The active substance telmisartan, which supports the work of the heart, is part of the drug
Mikardis Plus. Analogs, the price of which is slightly lower than the cost of this medicine, have a different composition.
The price of the drug and its analogues
The pricing policy for medicines may vary in different regions of the country. This is due to the features of delivery, the remoteness of the village from the manufacturer, the demand for medicine in a particular area. In general, the drug can be classified as affordable medical devices. Its price ranges from 800-900 p. The drug "Mikardis Plus" costs a little more: from 900 to 1100 rubles. Certified in the territory of Russia and Ukraine, the drug "Mikardis". Russian analogues on average have either the same price as the drug, or lower.
The drug "Mikardis" (tablets) - reviews, description of the action by patients
Many patients note that the effectiveness of Mikardis depends on the condition of the patient. If the disease progresses, you need to use along with this medicine also some others that will help stabilize the condition. Since this drug affects the functioning of the cardiovascular system, it should be prescribed only by a medical specialist. The patient cannot competently assess his condition and prescribe an adequate dose of the drug.
Like some similar drugs, the drug "Mikardis" has its own pattern of use. An individual therapy plan is developed for each patient in accordance with complaints and changes in health.