The human immunodeficiency virus is today the most dangerous and deadly for him. Doctors and scientists around the world are concerned about creating a cure for this disease. And if a vaccine against HIV and AIDS were invented, it could save tens of millions of lives. However, work is underway on this, and in the future this medication can be invented. A completely different question: when will this happen?
Future forecasts
Not so long ago, the biomedical center of St. Petersburg worked on the creation of this medicine, developing various options. A professor at the center, who runs the entire workflow, said that in the future, an HIV vaccine could be released in about five to six years. Regarding the development of the center itself, the first phase of testing their drugs began four years ago - in the fall of 2010. And these experiments were considered successful! However, the second phase began only this summer. Only this year we managed to get all the necessary permits and funds.
Clinical trials
What are they for and how do they go? In fact, everything is clear here. After all, this stage is necessary in order to find out exactly how this vaccine acts on the human body. The study is under strict control; volunteers are given only an experimental vaccine. Before testing the drug in humans, it was tested in animals - this stage showed the immunogenicity of the drug and its safety. And of course, the state examination gave one hundred percent confirmation that this drug can be included in clinical trials.
First stage
It should be recalled how the first stage went. People who did not have the immunodeficiency virus took part in it. There were 21 people, among whom were both women and men. They were divided into three groups, each of which had its own specific dose of medication (0.25, 0.5 and 1 milligram). As a result of tests, it was found that this vaccine is absolutely harmless to health. This was the main goal of the first phase. A few more conclusions were also made. Firstly, it was possible to find out that drug addicts are infected with only one particle of the virus. Secondly, some people who regularly come in intimate contact with those who have the immunodeficiency virus do not get sick. The body of these individuals seemed to block the disease. Here, scientists had several assumptions - they could have previously encountered a virus that is similar to HIV, and thus developed immunity directly to immunodeficiency disease. And finally, the third - it was possible to prove that HIV in the blood can be caught even on the first day of infection. And if you immediately begin to give the infected special medicines, then you can avoid the disease.
Second stage
In the next stage, 60 volunteers will participate, and all of them are infected, only the subtype virus. As a matter of fact, the HIV vaccine developed by the medical center is aimed specifically at combating this disease. Again, the participants will be divided into three groups, in the first two they will be administered the drug at 0.25 mg and 0.5 mg, but in the third they will use the placebo effect. That is, inoculation with saline. Who will be in which group is unknown. But the conditions are very harsh. The end of the HIV vaccine test is planned for the end of next year, 2015, and then the results will be summed up.
Features of the drug
The HIV vaccine being developed belongs to the fifth group according to the danger scale. In a word - it is completely safe and non-toxic. There is no infectious agent in this drug, so the ampoules used are eliminated in the usual way. And the fact that this HIV vaccine is safe was confirmed at the very first stage of the test. Actually about the name, this drug is designated as “DNA-4”. The medicine contains four special viral genes, I must say, this is enough to cover all parts of the genome. However, the scientists of the center are already in full swing developing another drug, DNA-5. But it’s too early to talk about how the new HIV vaccine will turn out, because the trials of the previous drug have not yet been completed.
How to deal with the virus
In order to cope with this disease, you need to make a lot of effort. After all, only strengthening your immunity, you can slow down the destructive effect of the virus. Today, there are many modern means and drugs that have virtually no side effects. Their main disadvantage is that a person is forced to take these medications for life. Otherwise, if you stop using them, the virus will go on the offensive. And they are very expensive. How to fight HIV? Firstly, you need to undergo antiviral therapy. Secondly, a vaccine against HIV, but it is now only at the development stage. Thirdly, the rejection of all bad habits, which include the use of alcohol, drugs, casual intimate contacts, etc. In fact, all of the above is a combined prevention. And she really helps.
Drug action
Attention should be paid to another Russian invention, but first you need to clarify something. Medicines against this disease have been created for a long time. They help, but not as effectively as necessary. And the thing is that existing medicines are not able to cope with the main property of AIDS - that it can mutate. However, the new drug was effective even after three viral mutations. The AIDS vaccine prevents the virus from multiplying in the body. It acts in such a way that reduces its concentration to those values that are less than even normative. This AIDS vaccine is the result of general work that began six years ago, in 2008. And optimistic forecasts of experts assure that this miraculous remedy is likely to become the main drug that will help cure a terrible ailment. Many pharmaceutical companies are already interested in investing in the further development of this medicine. And indeed, it is necessary for society. Indeed, from the moment the HIV epidemic began (that is, from the beginning of the 80s), almost 60 million people were infected with this virus and 25 million of them have already died.
Tests and Research
Some patients managed to experience the miraculous effects of this drug. In any case, people who dared to find out what a new HIV vaccine is, enthusiastically responded to this drug. Probably, the medicine is really effective - it is not for nothing that highly skilled specialists from several companies and research centers worked on its creation. In fact, this is a revolution in medicine, since this tool is based on nanotechnology. Lev Rasnetsov, the inventor of this drug, hopes that this HIV vaccine will be an innovation. This medicine was made on the basis of molecular compounds, which are allotropic forms of carbon (which include graphite, carbin and diamond). This medication blocks the affected cells of the body, slowly killing them. With this drug, you can maintain normal health. However, there is one minus, and it was mentioned a little higher - you need to use the drug for life.