Azelaic acid is a very popular ingredient in pharmaceuticals that is actively used in anti-acne therapy. It is found in small quantities in the human body, where it is formed in the process of lipid metabolism. For cosmetic and pharmaceutical purposes, it is obtained biochemically.
Basic properties
Azelaic acid has several interesting and, of course, useful properties.
Firstly, it has an anti-inflammatory effect and is able to stop the growth and reproduction of bacteria, which play a key role in the development of inflammatory processes in the sebaceous glands. It has a depigmenting, anti-acne effect.
When using creams containing azelaic acid in their composition, after a few weeks, the number of bacteria living on the skin is significantly reduced. It is very important that there is no risk of formation of strains resistant to its effects. Therefore, it is not at all "addictive" and is very effective even with prolonged use, even for several months.
Azelaic acid actively prevents keratinization of the upper layers of the skin. Due to this quality, it prevents clogging of pores, which means it prevents the appearance of comedones (black dots). In addition, under its influence, the process of skin pigmentation slows down or completely disappears . It inhibits the production of the natural dark pigment melanin, due to which the effect of light whitening is obtained.
Azelaic acid is an excellent antioxidant. This property, coupled with many other effects, makes it an effective cosmetic product.
Ointment and cream with azelaic acid, can be used during pregnancy. However, women who are breastfeeding should reduce the dosage and regularity of use.
When applied to the skin with azelaic acid, it penetrates the dermis and epidermis, 3.6% of it is absorbed into the bloodstream. It leaves the body almost unchanged, along with urine.
Remember, if you read that azelaic acid is present in the product, the cream or lotion will be much more effective than others.
Indications for use
- Youthful or common acne.
- Pathological hyperpigmentation. This includes pigmentation spots during pregnancy, pigmentation after skin injury, and other types.
- Seborrheic dermatitis.
- Rosacea.
Side effects
When choosing pharmaceutical preparations with azelaic acid, it is necessary to pay attention to the percentage of its concentration. This is due to the fact that in high doses, it can cause redness and slight burning of the skin. Therefore, for therapeutic purposes, agents are usually used in which its concentration is not more than 20%. In such quantities, it is non-toxic, does not have any side effects, and can be used for a long time.
It is also worth remembering that pharmaceutical ointments containing azelaic acid cannot be applied immediately after the deep peeling procedure . They are not recommended when consuming pepper food, alcoholic beverages, with irritated skin or after prolonged exposure to the sun.
Using funds with azelaic acid, its contact with the mucous membranes of the mouth, eyes, nose, ears, etc. should be avoided. In case of side effects, the dosage should be reduced or the use should be temporarily stopped.
Industrial use
Azelaic acid is also very widely used in the chemical industry for the production of polyurethanes, rubbers and polyamides. In industrial production, it is added to soap to avoid cracking.