In recent decades, in the field of professional cosmetology, the method of correction of the skin through restorative biological technologies has become increasingly popular. These include, in particular, rejuvenation by injection of autologous fibroblasts.
Scientific evidence
This technique has a serious biological soil and is based on the body's natural ability to regenerate. Fibroblasts are fibrous cells found in every human body. Their goal is the continuous production of the most valuable substances, on which the healthy state of the human body directly depends.
First of all, these cells synthesize the structural components of proteins, as well as connective fibers and hyaluronic acid. The presence in the tissues of these elements in the required quantity and in the right proportions ensures the stability of hydrostatic pressure in the cells and gives them elasticity. During life, as a person approaches adulthood, the percentage of fibroblasts in the skin decreases. They lose their elasticity and, under the influence of gravity, become flabby and saggy.
At the end of the 20th century, cell rejuvenation with fibroblasts was included in the methods of classical surgery. Reviews of the first patients to whom this technique was applied showed that in 100% of cases the use of injections took place without any negative consequences.
Sequencing
The collection of tissues for the preparation of the solution is carried out under local anesthesia. Samples are sent to the laboratory, where, within a few weeks, the clinic receives ready-made materials necessary for rejuvenation with fibroblasts. How the procedure occurs, can be observed in the photo below.
The skin of the face, as well as the neck, décolleté and hands are extensively injected. Shortly before the start of therapy, the areas designated by the doctor are carefully treated with anesthetic cream. The drug is administered using special thin needles. Once in the layers of the dermis, active cells begin to produce the most important proteins for the body (collagen and elastin), as well as hyaluronic acid and other elements that are an integral part of the matrix.
The remainder of the fibroblasts not used for injection, at the request of the patient, remain in the cryobank, where they are stored indefinitely at a temperature low in liquid nitrogen. They can be obtained at any time for repeated procedures.
Cellular rejuvenation with fibroblasts: the essence of the procedure
The renewal of connective regenerating cells not only accelerates the restoration processes in the structure of the skin, but also allows their correction. Along with folds, shallow scars and other aesthetic defects disappear.
Fibroblast rejuvenation is a complex of medical procedures, tailored to the individual characteristics of the patient and referred to as SPRS-therapy. It is carried out strictly in a clinical setting.
For injection, the surgeon takes samples of the patient’s skin and laboratory makes many copies of its structural elements. Since fibroblasts are their own, and not foreign, human cells, the procedure for their implantation occurs absolutely naturally. The body starts natural regenerative processes, which after a while becomes noticeable visually.
The injection procedure is painful no more than any of the so-called “beauty injections” and does not leave behind any visible traces, other than positive ones.
Rejuvenation course
Most often, the introduction of the required number of fibroblasts is carried out in two short procedures. They are held for 12 weeks at regular intervals. However, this schedule may vary, since SPRS-therapy involves an individual approach, depending on the particular characteristics of the patient's skin integument.
The result of the procedure is often obvious after the first session, which indicates the amazing speed with which fibroblast rejuvenation occurs. The photo below demonstrates the effect of ongoing recovery processes.
SPRS-therapy does not give side effects in the form of allergic reactions. Since fibroblasts are the main element of mesenchyme stem cells, the probability of their rejection by the body is excluded. The courses of therapy are perfectly combined with almost all other methods that currently exist in cosmetology.
Indications for the procedure
The introduction of cloned regenerating cells is indicated for people aged 40 years. However, this technique can be applied at earlier stages. In addition, it is worth remembering that saturation of the skin with fibroblasts is also made with the aim of correcting minor scars or defects.
The technology of introducing regenerative cells is recommended for people:
- with severe signs of aging;
- middle-aged (for the prevention of wilting of the skin);
- with various kinds of defecates (scars, smallpox, burns, etc.);
- wishing to begin the formation of fibroblasts in order to improve and maintain tone.
Patients who have indications for rehabilitation measures after cosmetic procedures (peeling, resurfacing, plastic surgery) may also be shown rejuvenation with fibroblasts. Reviews of this procedure indicate that it is best to collect samples for cell propagation at a younger age, when their ability to regenerate is highest.
The principle of action of embedded cells
Morphological studies of the dermis, artificially saturated with fibroblasts, indicate the extreme productivity of such technologies. Soon after the injection, newfound cells are fixed in small groups. This is due to the dosed introduction of biological material, which is characterized by weak diffuse properties.
Inside the intercellular fine-grained substance, synthesized collagen fibers begin to be observed , which is a direct result of active restoration work. Characteristic signs persist until 18 months, after which fibroblasts are fully integrated into the skin structure and become no more active than all its components.
After these processes, active cells can be reintroduced according to an individually selected scheme. As a rule, the effect of the repeated procedure has a brighter result, since the restoration processes in the skin are already running.
Benefits of Restorative Biotechnology
Fibroblasts introduced into the skin integument remain active for at least a year and a half. The necessary proteins are produced in the dermis, resulting in a natural renewal of cells. The intensity of the anti-aging effect throughout the duration of the action is parabolic in nature, increasing, and then gradually fading away. By the end of the period, the activity of the implanted cells begins to correspond as much as possible to the real age of the patient.
Signs of correction of age and other changes make up the following list:
- significantly reduces the number of folds and the depth of chronic scars;
- the skin tone is leveled, its elasticity returns;
- cell regenerative capabilities are obviously enhanced;
- pronounced rejuvenation is manifested.
Fibroblasts are cells responsible for the freshness of the skin and, ultimately, for the beauty of a person. Composing, among other elements, the dermis framework, they produce and organize various components, maintaining its necessary physiological state.
Contraindications and recommendations
The procedures for introducing new cells are not recommended in the following pathological conditions:
- active stage of an infectious disease;
- the presence of malignant tumors;
- impaired functioning of the immune system;
- rashes and other defects not associated with the action of infection.
In addition, this therapy is contraindicated in pregnancy and breastfeeding.
Fibroblast injections are a fairly productive basis for other procedures, the purpose of which is to restore the microstructure of the skin and correct its defects. Extensive practice of applying biological rejuvenation technologies shows that the impact of each cosmetic product applied to the SPRS therapy procedure is significantly enhanced.
So, such procedures are recommended to be combined with a lift using ultrasound and laser rejuvenation techniques. Also, more obvious results after the introduction of fibroblasts are given by mesotherapy and other techniques.