In the article, we consider that this is an RFMK blood test.
Human blood is one of the important objects for laboratory research, which are performed to obtain information about the health status of patients. Some parameters, for example, the level of glucose or leukocytes, are very well known to everyone, while others seem a mystery to patients. So, RFMK blood test. What is it? This symbol can be deciphered as a soluble fibrin monomeric complex, which reflects the condition along with the functionality of platelets in the blood.
About the study
A blood analysis of RFMC is carried out in order to establish their quantitative indicators in the blood plasma. RFMCs are particles of thrombi, whose number increases significantly in the presence of thrombosis of large vessels (for example, with pulmonary thromboembolism, thrombosis of other arteries and veins). The amount of RFMC in the blood plasma can significantly increase in patients with DIC, which is observed against a background of a sharp violation of blood coagulation, shock, injuries and extensive burns.
Many are interested in where you can take a blood test of RFMC. We will tell about it below.
Where does this study go?
A blood test of RFMC is given in a research laboratory according to the medical field or at the patient’s own will. Next, find out for what purpose this study is assigned.
What is this study prescribed for?
The work of the body is a special system in which everything is extremely interconnected. The normal functioning of systems and organs is possible only on the condition that absolutely every component works correctly. In addition, each organ must be healthy. In the event that a malfunction occurs (infection, inflammation, etc.), then this immediately affects the functioning of absolutely all systems. The circulatory system reflects any change and course of diseases in the body. Therefore, clinical and biochemical blood tests are so important for diagnosis.
Possible pathologies
An RFMC blood test makes it possible to determine if there are any deviations in the processes of hemostasis. So what exactly is fibrin monomeric complexes? We are talking about the smallest particles of blood clots, as well as red blood cells responsible for blood coagulation in humans. An increase in the number of these particles in a patient’s blood sample may indicate a possible risk of thrombosis or blood clotting. In this case, general blood circulation can significantly deteriorate. In addition, cells may simply not receive oxygen with beneficial enzymes that carry blood throughout the human body.
What is it - RFMK blood test, now it’s clear.
Preparing for analysis
Any analysis must be prepared in advance, in this case, blood biochemistry is no exception. For research, a laboratory assistant or doctor takes blood from the ulnar vein of patients. The sampling of this biological sample is carried out, as a rule, in the morning, as blood should be taken strictly on an empty stomach. Immediately before the test itself, in no case should you eat food with drinks, you can only drink ordinary water. The day before, you can’t eat foods that can affect blood coagulation (such foods include grapefruits, ginger, etc.).
Give the body a rest
A few days before the study on a soluble fibrin-monomeric complex, it is recommended not to overstrain the body if possible. In addition, you should not get involved in sports, but in addition, you should avoid fitness, swimming or overwork. Thus, in the framework of preparation, one should not engage in any physical labor. Distorting the results of the analysis can be emotional shock along with strong excitement. In addition, a few weeks before the test (in consultation with the attending doctor), the medication is necessarily stopped.
Norm
Normally, this analysis is considered negative. In the event that the formed fibrin particles are well displayed in the blood plasma within one hundred and fifty seconds, then this result is considered positive. The seconds during which fibrin formation occurs are translated using a special table into the quantitative values of RFMC. The indicators should be as follows:
- The norm of RFMC, as a rule, is from - 3.37 to + 0.01 milligrams per 100 milliliters.
- The maximum value in this case is 4 milligrams per 100 milliliters.
A high level in patients with RFMC may indicate activation of hemocoagulation processes. The greater the value of RFMC, the higher the risk of blood clots in large vessels.
RFMK increased, what does it mean?
Reasons for the increase
An increase in the amount of fibrin monomeric complex can occur due to the development of a number of diseases and some pathological conditions. A doctor may prescribe a study on RFMC as part of preventive goals in order to make sure that the indicator is normal, or it is done according to clinical indications.
So, RFMK is increased, which means it is important to find out in advance.
The reasons for the appointment of this blood test may be the following conditions:
- The presence of pathological conditions in which there is a violation of the functions of blood coagulability.
- The development of vascular thrombosis. This condition is complicated if the patient has a narrowing of blood vessels or blood biochemistry shows a very high cholesterol content. The presence of fatty deposits on the walls of blood vessels can interfere with blood flow. Why else can the RFMC be above the norm?
- The presence of DIC. Such a pathology leads to the appearance of a significant number of microthrombi inside the vessels, and blood flow may be impeded.
- The development of hemorrhagic vasculitis. This disease can be characterized by high bleeding, which occurs as a result of the inflammatory process in the vessels.
- The presence of severe injuries and physical damage to organs and tissues leads to increased platelet production, and, in addition, to a high content of fibrin monomeric complex.
Before surgery
A compulsory medical study with the study of hemostasis is prescribed as part of the planning of surgical operations. Analyzes should be normal, that is, demonstrate values from 3.8 to 4.0 milligrams per 100 milliliters. During conception or pregnancy planning through the IVF method, a complete analysis of absolutely all systems is mandatory. Biochemical blood tests for RFMC are also mandatory.
In some situations, the value of RFMC increases not for the reasons of any disease, but against the background of the physiological characteristics of the body. Prolonged physical stress, which is associated with difficult working conditions, can lead to an increase in this indicator. Strong prolonged stress can affect not only the nervous system, but also the general condition of the human body, including the hemostasis rate.
If RFMC is increased, what should I do?
When the patient’s emotional and physiological state returns to normal, the blood composition immediately normalizes. Otherwise, the doctor may prescribe a nutritional correction along with taking certain medications. At times, deviations in the fibrin monomer complex content are explained by congenital (i.e., certain hereditary) factors. In such cases, treatment is usually not required for patients.
A high rate can be reduced with the following blood-thinning drugs:
- Curantil or Phlebodia. They are taken three times a day for a month. But they are appointed separately, since their combination is unsafe.
- Folic acid. It is recommended to all pregnant women, especially in the early stages. If there is a threat of thrombosis, it can be prescribed from the first days until the birth.
- "Actovegin", which is prescribed in the form of injections for 2 weeks, after a month break, the therapy is resumed. A combination of injections and tablets is acceptable. First, injections are carried out for 2 weeks, after which tablets are prescribed.
What is the norm of RFMC in a blood test during pregnancy? About it further.
Pregnancy rates
Women who are in this position, a lot of tests are mandatory, and, in addition, clinical trials. Careful monitoring of the state of the body of expectant mothers and babies allows you to adjust indicators in time or perform appropriate treatment. For healthy women, the birth process, as a rule, does not pose a threat, on the contrary, the body's natural defense systems work correctly. For patients who differ in certain deviations in the analysis, there are risks of complications during, and, in addition, after the birth of the baby. Among other things, the state of health of the mother affects the development of the baby.
Among other studies and tests, pregnant women are prescribed an analysis for RFMC. Evaluation of hemostasis in this condition is very important, and doctors do this analysis several times. In the body of a pregnant woman, the content of fibrin monomeric complexes is almost always higher than the accepted norms for a healthy person. This is primarily due to the natural desire of the mother's body to self-preservation.
During this period, the woman’s body is preparing for the upcoming birth and possible concomitant bleeding. Thus, an increased blood clotting rate is ensured by an increased platelet count to prevent extensive blood loss. The RFMK index can rise gradually, doctors consider the best indicator of a fibrin monomer complex 5 milligrams per 100 milliliters. This is the optimal amount of RFMC, which does not pose a threat to the health of pregnant women as such.
The norm in pregnant women
Permissible norms of this indicator are usually the following:
- In the first trimester, the norm is from 5 to 5.5 milligrams per 100 milliliters. During this period, no global changes are carried out, but the formation of the placenta starts.
- In the next trimester, the norm rises to 6.5 milligrams per 100 milliliters. The body of a pregnant woman begins to be rebuilt taking into account the needs to create optimal conditions for the child.
- In the last trimester, the woman’s body prepares for childbirth and possible emotional stress. The body uses its resources as efficiently as possible, and the level of RFMC rises to 7.5 milligrams per 100 milliliters.
In the event that the permissible norm of the content of the fibrin monomer complex in the blood for pregnant women is exceeded, the reasons for this can be very serious. Thrombosis or even thrombophilia may occur. As a rule, such a condition is purely hereditary. At the same time, the future mother can behave extremely defiantly and sometimes even aggressively in her relations with others. Miscarriages are also possible. The use of modern methods of treatment can reduce such risks.
A blood test to show RFMC is performed as part of routine examinations of different categories of the population. A biochemical blood test is prescribed by a doctor to patients according to relevant indications. Such a study can always be done at will. To do this, you just need to contact the therapist for a referral.
Conclusion
Thus, soluble fibrin monomeric elements (RFMCs) are a complex of degradation products of fibrinogen and fibrin. The determination of their quantity is used in laboratory diagnostics of a thrombotic process associated with a state of hypercoagulation.
We examined the decoding and norm of the analysis of blood RFMK.