Estradiol belongs to the group of female sex hormones that are produced by the adrenal cortex and genitals. In the male body, most of estradiol is produced with the participation of aromatase by converting the hormone testosterone. In the estrogen group
estradiol is most active. It has a strong effect on the body, forming a physiology of the female type and supporting a number of vital processes. Its overabundance is fraught with various functional disorders. This is especially noticeable on the example of the male body. Therefore, when the hormone norm is exceeded, it becomes relevant not only the question of how to lower estradiol in a woman, but also how to balance its content in the body of a man.
What is estradiol for a man for?
Despite its name, female sex hormones play an important role in the male body. Estradiol is involved in the enrichment of bone tissue with calcium. With its help, there is a strengthening and growth of bones. This hormone accelerates metabolic processes in the body, supports the functioning of the nervous system and fights “bad” cholesterol, reducing the likelihood of cardiovascular disease. In addition, estradiol supports male function by participating in sperm production. All this speaks of the exceptional importance of this hormone. However, with its overabundance
significant changes occur in the body.
Why is there a need to lower estradiol?
With an increase in estradiol, the appearance of a man changes. There is a rapid accumulation of adipose tissue and a decrease in muscle mass. Estradiol transforms the body, giving it female forms. Gynecomastia often occurs, expressed in an increase in the volume of the mammary glands. Hormonal failure leads to problems in the cardiovascular system. Hypertension, atherosclerosis, or a heart attack may develop. Unlike those who have low estradiol hormone, men with an elevated level of this hormone suffer from a disorder of the psycho-emotional sphere. They are prone to excessive irritability, anxiety, stressful conditions, as well as fatigue. In addition, estradiol should be lowered to avoid prostate adenoma and problems with the genitourinary system. Perhaps the occurrence of erectile dysfunction and even the onset of infertility. If you suspect a hormonal imbalance, you should perform a blood test and establish the level of female hormones.
How to lower estradiol?
Drugs that reduce the level of female hormones in the male body, according to the principle of action, can be divided into two groups. The first includes antiestrogens. They do not allow estradiol to actively affect the body. However, these substances do not change the level of hormones in the blood. Examples of antiestrogens include clomiphene, tamoxifen, and toremifene. Estradiol can be reduced with the help of drugs of the second group. The principle of their action is to suppress aromatase. The conversion of testosterone to estrogen is slowed, and the overall level of estradiol is reduced. Aromatase inhibitors include aromazine, anastrozole, letrozole.