How to increase anti-muller hormone (AMH)? This question is of interest to many women suffering from infertility. The level of this substance in the blood indicates a supply of follicles in the ovaries, which decreases significantly with age. During menopause, the reproductive system ceases to function, and the content of AMH tends to zero. However, there are cases when an extremely low level of the hormone is observed in young women. Is it possible to increase it? We will consider this issue in the article.
What is AMG
How to increase anti-muller hormone? To answer this question, it is necessary to understand the mechanism of egg formation.
Even in the prenatal period of development in girls, a certain supply of follicles in the ovaries is laid (ovarian reserve). Throughout life, it is consumed. The number of future eggs decreases not only during ovulation, but also during pregnancy, as well as when taking hormonal contraceptives. To increase this stock is no longer possible. It is steadily declining with age. In women after 35 years, the ovarian reserve in most cases is significantly reduced, and during menopause it is zero.
Ovarian reserve is also called antral follicles. These cells secrete antimuller hormone (AMH). Its level indicates the number of remaining future eggs. The lower this indicator, the less likely it is to conceive.
A decrease in AMH in middle and old age is a natural phenomenon. However, ovarian reserve depletion is often observed in young women planning a pregnancy. How to increase anti-muller hormone? What to do with low rates of AMH? To answer these questions, you need to understand what the functions of this substance are.
Hormone function in the body
Today, a blood test for AMG is prescribed for many women who have problems conceiving. However, the anti-Muller hormone was discovered relatively recently. Scientists have found that this substance plays the following role in the body:
- contributes to the maturation of the follicle and the formation of an egg;
- regulates the production of other female hormones;
- prepares the body for pregnancy;
- creates the conditions for the operation of pituitary gonadotropic hormones.
Norma AMG
To determine the level of anti-Mullerian hormone, it is necessary to submit venous blood for examination. The test is carried out during the period from the second to the fifth day of the menstrual cycle.
The rate of AMH in women depends on age. The table below shows the acceptable indicators of this hormone for different categories of patients:
Patient's age, years | AMG level, ng / l |
0 - 16 | 1 - 3.3 |
17 - 19 | 1.9 - 2 |
20 - 39 | 2.2 - 7 |
40 - 55 (and older) | 1.1 and less |
Is it possible to increase the anti-muller hormone in women? If the decrease in AMG is associated with natural age-related changes in the reproductive system, then it is impossible to influence this indicator. Modern medicine is not able to stop the aging process and restore the ovarian reserve given to every woman at birth.
However, a decrease in the level of AMH in reproductive age is often associated with various diseases of the reproductive and endocrine systems. In these cases, it is possible to increase the antimuller hormone. But for this it is necessary to accurately establish the cause of its fall and conduct treatment of the underlying pathology.
Symptomatology
AMH levels directly affect fertility. Therefore, most women with reduced antimuller hormone suffer from infertility. A history of failed IVF attempts may also be noted.
In addition, in some patients the following pathological signs are observed:
- menstrual irregularities;
- amenorrhea (absence of menstruation);
- hirsutism (excessive hair growth on the face and body);
- menopause before the age of 40;
- overweight or too low weight.
This additional symptomatology is far from always noted. Infertility is often the only manifestation of low ovarian reserve. After all, this hormone does not directly affect the regularity of menstruation. However, many diseases accompanied by a decrease in anti-Muller hormone can lead to malfunctions of the menstrual cycle.
Reasons for hormone decline
The main reason for the decline in AMH is the deterioration of the reproductive function of the ovaries due to age-related depletion of the ovarian reserve. If the antimuller hormone is lowered in young women, then the following conditions and diseases can be the cause of this:
- anovulatory cycles;
- decreased sensitivity of AMG receptors;
- delayed puberty in adolescent girls;
- infertility of endocrine etiology, accompanied by a lack of ovulation;
- exhausted ovary syndrome;
- obesity;
- Stein-Leventhal syndrome (polycystic ovary syndrome);
- tumors of the reproductive organs.
How to increase anti-muller hormone with these pathologies? In each case, specific treatment methods are used. Usually, after eliminating the cause of a decrease in AMH, its level normalizes.
Forecast
If we are talking about hormonal disorders, then it is quite possible to restore reproductive function. To do this, you need to undergo a course of drug therapy.
How to increase anti-muller hormone in women with early menopause? In these cases, the prognosis of the restoration of childbearing function is unfavorable. Natural conception is no longer possible due to the complete depletion of the ovarian reserve. For such patients, doctors recommend using an IVF program using donor eggs.
Often, patients are interested in the question: "Is it possible independent pregnancy with low AMH?". Such cases in medicine have been noted. However, this is rather an exception to the rule. Most often, a decrease in ovarian reserve creates big problems with conception. In addition, low AMH in a pregnant woman can adversely affect fetal development. Therefore, in any case, it is necessary to undergo a course of treatment.
Additional research
To answer the question: “Is it possible to increase the anti-Muller hormone in women?”, It is necessary to conduct a comprehensive examination of the reproductive function of the patient. With reduced AMG, the doctor usually prescribes additional tests. It is necessary to determine the level of the following hormones in the blood:
- FSH;
- LH
- estradiol;
- inhibin B.
It is very important to pay attention to the level of follicle-stimulating hormone. A high FSH content with low AMH usually indicates menopausal changes in the ovaries and the onset of menopause.
In addition, an pelvic ultrasound should be done. It helps to determine the reserve of follicles and the presence of ovulation.
Stimulation of ovulation
How to increase anti-muller hormone in women with medication? Such treatment can only be prescribed by a doctor, taking into account all the diagnostic information. It is necessary to eliminate the cause of the decrease in AMH.
Gonadotropic drugs can only temporarily increase the antimuller hormone in women. Ovulation stimulants cannot increase the egg reserve. However, in some cases, their use is justified and can lead to a long-awaited pregnancy.
For example, if a patient is diagnosed with lack of ovulation on the background of endocrine disorders, then gonadotropic hormones will contribute to the maturation of follicles and the formation of an egg. This will cause a temporary rise in the level of anti-Muller hormone. The following drugs are prescribed for the treatment of endocrine infertility:
- Menogon
- Humegon;
- Pergonal;
- "Chorionic gonadotropin."
These drugs are used according to a special scheme. Usually, drugs based on the hormones FSH and LH (Menogon, Humegon, or Pergonal) are introduced into the first half of the menstrual cycle. In this case, the maturation of follicles is constantly monitored by ultrasound. When ovulation approaches, a large dose of Chorionic gonadotropin is administered to the patient.
For polycystic ovary syndrome, Klostilbegit tablets are prescribed. They do not contain hormones, but at the same time they can stimulate ovulation. They are taken from 5 to 9 days of the cycle. The use of this drug led to the onset of a long-awaited pregnancy in many patients.
If a woman has signs of premature ovarian exhaustion, then hormonal contraceptives are prescribed:
- "Janine";
- Jess
- Rigevidon;
- Triquilar;
- "Diane 35".
The use of such funds allows the ovaries to "rest" for several months. After drug withdrawal, part of the patients restore reproductive function and increase the level of AMH.
It is very important to remember that hormone therapy can be carried out no more than 3 months. After all, the use of drugs to stimulate ovulation leads to an even greater consumption of ovarian reserve. Prolonged hormone intake depletes an already low egg supply.
DHEA preparations (DHEA)
How to increase anti-muller hormone? This question for many years worried not only patients, but also medical scientists. And only recently have been created tools that slow down the aging process of the ovaries. These are drugs based on the hormone dehydroepiandrosterone (DHEA).
Officially, these funds are referred to dietary supplements, and not to medicines. However, they have a rather strong effect on the body. Dehydroepiandrosterone stops premature ovarian depletion and age-related changes in the ovaries.
These nutritional supplements are available in capsule form under the trade name Natrol DHEA. However, they should never be taken without a doctor’s prescription. Indeed, AMH is often reduced in women with high levels of androgens. In this case, such supplements can only exacerbate hormonal disorders. Therefore, before using DHEA preparations, it is necessary to take a blood test for androgens and dehydroepiandrosterone.
Vitamin preparations
With low AMH , administration of complexes with vitamin D3 (cholecalciferol) is also indicated. They are prescribed together with hormones or DHEA drugs. This vitamin has the following effects on a woman's body:
- stimulates follicular maturation and ovulation;
- increases the likelihood of fertilization;
- contributes to the successful implantation of a fetal egg.
Cholecalciferol is part of the following complex drugs:
- "Alpha D3-Teva";
- "Calcium-D 3 Nycomed";
- "Complivit Calcium D3";
- "Natekal D3";
- "Vitrum Calcium + Vitamin D3".
It is also useful to regularly visit the sun. Ultraviolet rays contribute to the production of vitamin D3 in the body.
Diet
Is it possible to increase anti-muller hormone through diet? Of course, proper nutrition alone cannot improve reproductive function. However, diet is an integral part of treatment. For women suffering from infertility due to low AMH, doctors recommend consuming the following products:
- low-fat sea fish;
- caviar;
- offal (liver, kidney);
- egg yolks;
- fresh fruits and vegetables;
- potatoes;
- oat dishes;
- mushrooms.
These products contain useful substances that contribute to the normalization of hormonal levels.
At the same time, fatty, spicy and salty foods, energy drinks, and also all types of fast food should be excluded from the diet. It is very important not to drink alcohol and stop smoking. After all, bad habits extremely negatively affect the quality of the eggs.
Homeopathy
In pharmacy chains you can find homeopathic preparations of the German company "Hil". Reproductologists recommend taking them as an additional treatment for infertility. With low AMH, the following agents are indicated:
- "Aquarium Composite";
- Mulimen
- Gynecochel.
The preparations contain extracts from the pituitary and sexual glands of animals, plant extracts and minerals. This composition helps to normalize reproductive function and regular ovulation. However, these funds are not recommended to be taken on their own, since homeopathic treatment is not indicated in all cases.
It should be remembered that such therapy takes quite a long time. In this case, the regularity of taking drugs and following dietary rules is very important.
Folk remedies
How to increase the anti-muller hormone in women with folk remedies? This is not possible in all cases. If the patient has a sharply reduced ovarian reserve at a young age, this indicates a serious endocrinological or gynecological pathology. With such diseases, it is difficult to do without hormone therapy. However, the use of infusions and decoctions of medicinal herbs will be a good addition to the main treatment.
Next, we will consider how to increase the anti-Muller hormone folk remedies based on the pine forest and red brush. These herbs are sources of natural estrogen.
To prepare the infusion, you need to take 50 g of dry grass of the uterine uterus and place in 250 ml of vodka. The composition is kept for 2 weeks in a dark place. In the same way and in similar proportions, a tincture of a red brush is prepared. You can also purchase ready-made preparations from these plants at the pharmacy.
Infusion of the uterine uterus is taken for 1 month, 30 drops three times a day. This tool is recommended to eat before meals. Treatment is carried out from 5 to 22 days of the cycle. Over the next month, the composition of the red brush is taken in the same way. Herbal therapy courses are repeated and alternated for six months.
Treatment with a uterus and a red brush is especially effective for young women (up to 30 years old). The use of herbs helps to achieve pregnancy even with initially low AMH.
How to increase anti-muller hormone by folk remedies for women of more mature age? In this case, the collection of several herbs will help normalize the reproductive function:
- oregano;
- sage;
- daisies;
- yarrow;
- St. John's wort
- nettles;
- plantain.
It is first necessary to dry and grind these plants. Then take 1 tablespoon of each herb and place in a thermos. Collection pour 1 liter of boiling water and insist 8 hours. This tool is taken in 1 glass three times a day.
It must be remembered that all traditional medicine related to treatment are accepted only after consultation with the attending physician.
Patient Reviews
Patient reviews about the use of hormones with low ovarian reserve are rather controversial. Some women have had a long-awaited pregnancy after a course of treatment with gonadotropins and Klostilbegit. An increase in the level of anti-Muller hormone was noted, although it was temporary.
However, often the use of hormones did not lead to the desired result. Moreover, in some patients, artificial stimulation of ovulation caused an even greater drop in AMH. Numerous IVF attempts have failed.
Positive feedback from the patient is left about DHEA preparations. Doctors often prescribe these nutritional supplements to women over 35 years old before undergoing IVF. In many cases, this has led to an increase in AMG. As a result, smaller doses of hormones were required to respond to the ovaries. Egg quality has also improved.
Good reviews were received from herbal uterus and red brush herbal remedies. These funds have helped many women increase AMH and restore ovulation. It is important to note that decoctions and infusions were used in conjunction with medications, vitamins and diet. Such an integrated approach to treatment in many cases has led to the onset of a long-awaited pregnancy.