Strofantin, a Latin prescription and description of the drug will be discussed in this article. If heart failure is observed, it expands the stroke (that is, the amount of blood ejected by the heart into the bloodstream during one contraction) and the minute (the amount of blood ejected by the heart per minute into the bloodstream) heart volume helps to better empty the ventricles, resulting in a decrease the size of the heart. The effect of the use of this drug is observed three to ten minutes after intravenous injection. Its maximum effect is achieved in the period from half an hour to two hours after saturation is achieved. The drug is effective from one to three days.
Recipe in Latin "Strofantina" may interest medical students.
Chemical and biological processes in the body
There is an almost complete absence of a cumulative effect.
The drug is distributed fairly evenly; to a slightly greater degree, concentration occurs in the tissues of the adrenal glands, liver, pancreas, and kidneys. One percent of the drug is found in the heart muscle. In relation to blood plasma proteins - five percent.
It is excreted by the kidneys in its original form, without undergoing biotransformation. Approximately 85-90% is released per day, the concentration of the drug in plasma is reduced by fifty percent after eight hours. Complete elimination from the body occurs in the period from one to three days.
To the drug "Strofantin" the recipe in Latin will be given below.
Indications for use
Chronic heart failure of the second or third stage, various cardiac arrhythmias, including atrial fibrillation, supraventricular tachycardia. Remember that only a doctor prescribes the drug.
Dosage
The recipe for the Latin solution "Strofantin" indicates the following:
- The drug is administered intramuscularly and intravenously. Only in emergency situations, if the use of cardiac glycosides is impossible - inside.
- For injection into the vein, a solution of the drug 0.025% is taken, diluted in a volume of ten to twenty milliliters of a glucose solution (5%) or a sodium chloride solution with a concentration of 0.9%. This procedure is carried out slowly, about 5-6 minutes (if you enter quickly, shock may occur).
- A solution of this drug is also used in drops (in 100 ml of a solution of dextrose or sodium chloride of the same percentage concentration, as described above). With this form, the toxic effect develops less frequently.
- The maximum doses of the drug intravenously for an adult: a single dose is two milliliters, that is, two ampoules, and a daily dose is two times more, that is, 4 ampoules (4 ml, respectively).
- If intravenous administration is not possible, then it is used intramuscularly. To reduce sharp pain in this case, you first need to inject 5 ml of procaine solution (2%), and then through the same needle - the required dose of "Strofantin K", which is diluted with 1 ml of a 2% solution of procaine. For intramuscular administration, doses are increased one and a half times.
The daily dose for children, or the saturation dose, when using Strofantin K solution at a concentration of 0.025%:
- a newborn child - from 0.06 to 0.07;
- up to three years: from 0.04 to 0.05;
- from four to six - from 0.4 to 0.5;
- seven to fourteen: 0.5 to 1.
The maintenance dose contains from half to one third of saturation. Is Strofantin well tolerated? The recipe in Latin will be presented below.
Side effects
From the cardiovascular system: atrioventricular block, bradycardia, ventricular fibrillation, extrasystole, ventricular paroxysmal tachycardia.
From the gastrointestinal tract: vomiting, nausea, diarrhea, decreased appetite.
From the central nervous system: dizziness and headaches, sleep disturbances and color perception, fatigue, drowsiness, psychosis, depression, confusion, less often - staining objects around in yellow and green, "flies" in front of the eyes.
Other side effects: urticaria, allergic reactions, nosebleeds, thrombocytopenia, petechiae, decreased visual acuity, thrombocytopenic purpura less often. If the drug was used intramuscularly, there may be soreness at the injection site.
The Latin prescription “Strofantina” can be checked with your doctor.
Application limitations
Among the contraindications are:
- high sensitivity to the composition of the drug;
- Wolf-Parkinson-White syndrome;
- sinoatrial complete block or intermittent atrioventricular;
- atrioventricular block of the second degree;
- glycosidic intoxication.
With caution, taking into account the ratio of benefits and risks, it should be used if there is a sinus node weakness syndrome without artificial pacemaker, first-degree atrioventricular block, presence of Morgagni-Adams-Stokes attacks in the history of the disease, the possibility of unstable passage through the atrioventricular node, hypertrophic obstructive cardiomyopathy, cardiac asthma in patients with mitral stenosis (if there is no tachysystolic form of atrial fibrillation), acute myocardial infarction, isolated bath mitral stenosis with a rare frequency of contractions of the heart, etc.
The drug "Strofantin" in Latin in ampoules should be given to a pharmacist.
Application features
Pregnant women and those who are breastfeeding should not use the drug, since there are no scientific studies confirming the safety of its use.
In the presence of impaired liver function, liver failure should be used carefully. The same applies to patients with renal failure.
You can use the drug to treat children, because there is no age limit for taking it. Elderly people should be careful.
Separate directions
With maximum caution, it is possible to use the drug in patients who have atrial extrasystole, thyrotoxicosis. Since the therapeutic index is low, serious medical supervision and individual dose administration are required during treatment.
If renal excretory function is impaired, the dose should be reduced to prevent glycosid intoxication.
Hypomagnesemia, marked dilatation of the cardiac cavities, hypokalemia, hypernatremia, alkalosis, hypercalcemia, advanced age contribute to an increase in the likelihood of an overdose of the drug. Particular caution and control with an electrocardiograph are necessary if atrioventricular conduction is impaired. To the means of "Strofantin", the attending doctor should write a prescription in Latin.
If normo- or bradycardia is expressed, as well as mitral stenosis, chronic heart failure develops due to a decrease in diastolic filling of the left ventricle. By increasing the contractility of the heart muscle of the right ventricle, Strofantin K contributes to a subsequent increase in pressure in the arteries of the pulmonary trunk, which can cause pulmonary edema or aggravate left ventricular failure. For patients with mitral stenosis, drugs of this kind are prescribed for atrial tachyarrhythmias or in the event of insufficiency of the right ventricle. If the patient has WPW syndrome, then Strofantin K helps to reduce atrioventricular conduction, while helping to conduct impulses using additional paths, bypassing the atrioventricular node and causing the development of paroxysmal tachycardia. As one of the methods of monitoring digitalization, plasma glycoside concentration monitoring is used. This is confirmed by the medicine "Strofantin" in Latin prescription and instructions.
If intravenous administration was carried out quickly, then ventricular tachycardia, bradyarrhythmia, atrioventricular block, and even cardiac arrest may develop. During the maximum exposure, the appearance of extrasystole, in some cases in the form of bigeminia, is possible. To prevent this effect, the desired dose can be divided into two or three injections into a vein, or the first dose can be administered intramuscularly. If the patient had previously been prescribed cardiac glycosides of a different type, before Strofantin K is administered intravenously, it is necessary to take a mandatory break of five to twenty-four days, depending on how pronounced the cumulative signs of the previous drug are.
Impact on the management of various mechanisms and driving vehicles
During therapy with this medicine, it is recommended to refrain from driving and engaging in activities that pose a potential danger, require high concentration of attention and quick reactions.
Storage time and conditions
Store this medicine at a temperature not exceeding 25 degrees Celsius. The place where the drug is located should be inaccessible to children. Shelf life is three years.
It is released from pharmacies only by prescription.
Many are interested in the remedy "Strofantin" in Latin recipe and analogues.
You can replace the drug:
- Korglikon;
- Amrinon
- "Celanide";
- Adonis Bromine;
- Cardiovalenom;
- Dobutamine
- "Cardompin";
- digitalis leaves and some other means.
special instructions
This description of the drug "Strofantina K" is a simpler and more comprehensive interpretation of the official instructions for its use. Before you purchase or use the drug for its intended purpose, you need to get qualified medical advice from a doctor and read the annotation, which is approved by its manufacturer. The information provided on this drug is for informational purposes only and cannot be used as a guide to self-treatment. Only the attending physician has the right to prescribe the drug, as well as establish individual doses and application procedure.
Recipe in Latin "Strofantina"
Strophantinum K
Rp .: Sol. Strophanthini K 0.05% 1.0
D. td N 10 in amp.
S. 0.25-0.5 ml slowly into a vein, dilute before that in ten to twenty milliliters of a glucose solution (20%).