Arthritis is an inflammatory lesion of intraarticular tissue. Symptoms of the disease are visually manifested by reddening of the skin and severe swelling in the focus of inflammation.
With the disease, an increase in temperature in the affected joint can be observed. The duration and course of arthritis can be divided into acute and chronic. As a rule, two main groups of joint tissue disease are distinguished, depending on the provoking sources - inflammatory and infectious.
Therapeutic measures for infectious arthritis are carried out comprehensively with the use of antibiotics. During the treatment of joint destruction of autoimmune inflammatory genesis, antibacterial agents are not recommended.
Pharmacological actions
Antimicrobials inhibit and eliminate harmful bacteria that have entered the human body, or significantly inhibit their spread. Drugs that are active against gram-positive and gram-negative viruses are called broad-spectrum antibiotics. Medicines that are active against a certain type of bacteria belong to the group of antibacterial agents with a narrow spectrum of action.
Before using an antimicrobial agent, an analysis of the sensitivity of pathological microflora to different types of antibiotics is considered mandatory. After receiving the research results, the most effective medication is chosen.
Indications
With arthritis of an infectious origin, antibacterial agents must be present as part of combination therapy. They are prescribed, as a rule, in the following conditions:
- A protracted disease in which, due to inflammation in the joint tissue of a patient, severe pain and limited joint function during active and passive movements are disturbing.
- Exacerbations of chronic diseases of the nasopharynx, during which the symptoms of arthritis become more pronounced.
- Infectious diseases of the joints.
- Diseases of the gastrointestinal tract (includes pathology of the digestive apparatus from the oral cavity, pharynx and esophagus to the anal sphincter).
Release form
What antibiotics treat arthritis? Antimicrobial medicines prescribed for arthritis therapy have the following therapeutic forms of release:
- Solution.
- Ointments and liniment.
- Suppositories.
- Drops.
- Suspension.
- Aerosols.
Self-medication is strictly contraindicated, since only a doctor determines the complexity of the course of the disease and prescribes an effective medicine.
Antibiotics for rheumatoid arthritis
This type of arthritis involves inflammation of the joint tissue, which is provoked by beta-hemolytic streptococcus and is accompanied by destructive lesions.
Medical specialists with rheumatoid arthritis are extremely rarely prescribed antimicrobials. The therapeutic measures recommended by them are aimed at eliminating pain, reducing swelling and inflammation.
Treatment of rheumatoid arthritis with antibiotics by eliminating the bacterial source, which is considered the main cause of the appearance of the pathological condition of the joints, is an effective method.
Antibacterial agents for arthritis and arthrosis
Antimicrobial therapy is actively used to eliminate certain groups of joint diseases. Such a pathological process includes septic arthritis, accompanied by the ingress of the pathogen into the intraarticular fluid.
Taking antibiotics for arthritis and arthrosis is considered justified and mandatory if the disease is provoked by a bacterial infection.
When patients turn to a medical specialist for help, many already have pronounced signs of arthritis:
- sharp pain;
- limited movement.
Therefore, the main task of the doctor in a short time to establish a diagnosis and prescribe effective treatment. If there is a bacterial infection in the body, the hematogenous pathway of the pathogen from the focus to the joint tissues should be considered.
The selection of a more effective antibacterial agent is carried out depending on the type of infection. What antibiotics for arthritis of the knee joint can be taken?
With knee damage, you can use cephalosporins and fluoroquinolones, as well as macrolides, for example:
- Erythromycin.
- Josamycin.
- "Azithromycin".
- Clarithromycin.
- Cefepim.
They also treat arthritis with antibiotics containing fluoroquinolone (Ofloxacin) or macrolides (Sumamed).
If the causative agent of the disease entered the joint with blood flow as a result of urogenital infections, tetracycline drugs are necessary:
- Tetracycline.
- "Metacycline."
- Doxycycline.
A person with inflammatory joint damage and severe signs of an upper respiratory tract infection is prescribed arthritis treatment with antibiotics of the penicillin group and cephalosporin series:
- "Carbenicillin."
- "Acosicillin."
- Ampicillin.
- "Cefazolin".
- "Cephalexin".
- Cefotaxime.
In case of intestinal infection, which is complicated by arthritis, it is recommended to use medications that include fluorooxyquinolones (Lomefloxacin, Ofloxacin).
Reactive arthropathy is an ailment that is difficult to treat with medication. Antibiotics for reactive arthritis:
- Ofloxacin.
- Roxithromycin.
- Clarithromycin.
- Erythromycin.
The duration of antibiotic therapy is one week.
Can antibiotics be used during pregnancy?
In the treatment of arthritis in the gestational period, the use of antimicrobials is contraindicated. In the first three months of pregnancy, it is not recommended to use antibacterial agents in any form of release to eliminate arthritis, because the formation of the main systems in the fetus occurs.
If there is a need to use antibiotics for the urgent elimination of arthritis in the first trimester, you need to abandon the course of these drugs and choose something less toxic.
Antibiotic therapy does not mean that the baby will have health problems after birth. For the proper development of the unborn child, the doctor may prescribe certain medical studies.
Contraindications
The modern pharmaceutical market annually increases the range of drugs. Each group of antibacterial agents has its own prohibitions on use. The main contraindications for taking antibiotics for arthritis are:
- pregnancy;
- allergy (immunopathological process, which is expressed by increased sensitivity of the immune system when exposed to an allergen);
- damage to the kidneys and liver;
- diseases of the stomach and intestines.
Side effects
With arthritis, antibiotic therapy is not considered the main component of drug therapy. Incorrect use of them will cause damage to the body. Antibiotics overwhelmingly affect the immune system, reduce the body's resistance to viruses, and provoke a negative reaction from various organs and systems. Antimicrobials inhibit the beneficial intestinal flora.
If a medical specialist prescribed antibacterial agents to eliminate arthritis, then all doctor's prescriptions must be strictly followed. Failure to take antibiotics leads to negative dynamics, the occurrence of complications and an adverse outcome. What antibiotic can I take for arthritis?
To eliminate arthritis, the following drugs are prescribed:
- Sulfasalazine.
- Maxipin.
- Ceftibuten.
- Roxithromycin.
- "Metronidazole".
With improper use of the drug, patients may experience intolerance or increased sensitivity to the trace elements of the drugs, which should also be considered by the doctor when prescribing the medication:
- Azithromycin is more effective than Erythromycin, but its negative effect on the digestive organs leads to drug withdrawal. If treatment with Erythromycin is prescribed, then probiotics must be used additionally.
- "Clarithromycin" and "Roxithromycin" are quickly excreted from the body and have the least list of side effects.
- During pregnancy, a woman needs to completely abandon the use of antibacterial medications.
- Some drugs have a detrimental effect on the processes of formation, development and maturation of blood cells, blood microcirculation.
How to take antimicrobials for arthritis?
In the treatment of joint damage with antibacterial agents, antiflogistic, analgesic and regenerative drugs should be additionally used.
The duration of treatment may be several months, but this does not apply to antibiotics. Antimicrobial agents are prescribed in courses in a strictly defined dosage and mode. If chronic tonsillitis was the source of reactive arthritis , then the treatment contains antibiotics that are combined with other drugs to eliminate the focus of infection, for example:
- "Azithromycin" should be used once a day for one week.
- "Doxycycline" in capsules is taken one at a time twice a day. The duration of therapy is seven days.
Overdose
With the wrong use or non-compliance with the dosage of antibacterial agents to eliminate arthritis, the appearance of negative consequences is likely to occur, which are divided into groups:
- Provoking intoxication.
- Affecting the stomach and intestines.
- Causing autoimmune diseases (human diseases that manifest as a consequence of too high activity of the body's immune system).
With the accidental use of a large dosage of an antimicrobial agent to eliminate arthritis, intoxication of the body occurs:
- Penicillin and cephalosporin poisoning is characterized by attacks of nausea and vomiting, diarrhea. With the introduction of large doses of an intravenous drug of the penicillin group, epilepsy can occur and negative changes can be observed on the electrocardiogram.
- Overdoses of tetracyclines are rare, but they are dangerous for children. With prolonged use, rashes and Quincke's edema appear (a reaction to the effects of various biological and chemical factors, often having an allergic nature).
- Fluoroquinolone poisoning negatively affects the cardiovascular system, causing kidney dysfunction and toxic liver damage.
- Macrolides are considered the most harmless drugs and are well tolerated by patients. When using pharmacological preparations, there was no negative effect on the central nervous system. In case of poisoning, an antibiotic-associated diarrhea can occur (a disease that is characterized by the appearance of loose stools during or after taking antibacterial stools).
Storage
Antibacterial agents used to eliminate arthritis should be stored according to the requirements specified in the manufacturer's instructions for use. Most antimicrobial tablet formulations are kept at room temperature. The place where the drug is located should be difficult to reach for children. Ampoules with the medicine should be stored at a temperature of not more than thirty degrees. The prepared suspension must be kept in the refrigerator.
Shelf life
Antibacterial agents have different storage periods. The date of manufacture and the end date of sale are indicated on the packaging. Antibiotics that are used to eliminate arthritis should not be used after the deadline.
Reviews
According to reviews, if the first manifestations of arthritis occur, you should contact a medical specialist. A doctor with the help of modern diagnostics will be able to quickly determine the cause of the disease. Based on this information, she will select the correct antibiotic therapy. As a rule, with a timely visit to the doctor, the disease can be easily eliminated.
According to the reviews of medical specialists, it should be remembered that any inflammatory process in the joints can provoke severe pain in a person and worsen his overall well-being. And this means that in a short time it is very important not only to identify the ailment and its cause, but also to choose the most suitable therapy. However, it is not always possible to correctly diagnose at an early stage and to identify the source of his lesion.