"Ibuprofen" - instructions for use, indications, composition and reviews

The article will provide instructions for the use of "Ibuprofen", which is a well-known and well-studied drug with a wide range of effects. It is referred to as non-steroidal anti-inflammatory drugs. In addition, it is included in the list of essential drugs on the recommendation of WHO. Next, we consider the features of the application, as well as important tips with recommendations for using this medication.

The composition of the drug and its pharmacological properties

According to the instructions for Ibuprofen, the active ingredient is the ibuprofen component of the same name. Other ingredients are microcrystalline cellulose along with croscarmellose sodium, silica, magnesium stearate and corn starch.

Ibuprofen is a derivative of propionic acid. This medicine is endowed with an antipyretic and anti-inflammatory property. In addition, the tool has an analgesic effect on the body in the presence of pain of various localization. The active ingredient is well absorbed and rarely causes adverse reactions.

Release Forms

In pharmacies, tablets, ointment and ibuprofen syrup are sold.

1. Tablets. They have a light pink or pink color, a round biconvex shape and a smooth surface. The main active ingredient of the drug is ibuprofen, the content of which in one tablet is 200 mg.
2. Ibuprofen Syrup. The instruction indicates that in liquid form, the preparation is made by the EKOlab company in the form of a 2% solution, packed in 100 ml dark glass bottles. Such a suspension is characterized by a white-cream color, an orange smell and a slightly tart sweet taste. A measuring spoon is attached to the bottle, allowing you to dial the drug in a dose of 2.5 or 5 ml.
3. "Ibuprofen" ointment. The instruction reports that 1 g of ointment contains the active substance: ibuprofen - 50 mg; dimethyl sulfoxide - 100 mg; excipients: macrogol - 400, macrogol - 1500.

Pharmacokinetics

As the instructions to "Ibuprofen" indicate, the pharmacokinetics of this drug is as follows:

1. The drug is completely absorbed in the digestive system.
2. The maximum effect is achieved after half an hour, provided that it is taken on an empty stomach.
3. After eating, the action of "Ibuprofen" slows down, but as for absorption, it occurs in full.
4. If taken after a meal, the effect occurs after one or two hours.
5. The process of binding to blood proteins is carried out almost in full.
6. Full absorption in the synovial fluid is achieved two hours after ingestion. In this case, the concentration in the synovial fluid is achieved much higher in comparison with blood plasma.
7. The elimination half-life, as a rule, reaches three hours after administration.
8. Metabolism occurs in the liver, and the drug is excreted by the kidneys in the form of conjugates.

This is stated in the instructions for use with Ibuprofen tablets. In order to achieve the best effect, Ibuprofen is used in the minimum dosage, and if necessary, you can repeat the dose after an hour. Do not exceed the recommended dose, as well as independently extend the period of use. Such measures can lead to side effects, in addition to serious consequences for the patient’s health.

Indications for use

In accordance with the instructions to "Ibuprofen", in order to minimize the risks of adverse reactions, the use of this drug is recommended after a meal. Active active ingredient can damage the gastric mucosa. Against the background of constant abuse of this drug, the formation of erosion or ulcers is likely, and severe liver and kidney pathologies are not excluded. Ibuprofen has the following indications:

1. The presence of rheumatoid arthritis.
2. The development of gout, osteoarthritis, or ankylosing spondylitis.
3. The appearance of neuralgia and myalgia of various origins.
4. The presence of radiculitis or adnexitis.
5. The presence of otolaryngological diseases.
6. The appearance of headaches and toothaches.
7. Getting soft tissue bruises and sprains.
   

What does the instructions for use for Ibuprofen for children tell us? In patients in childhood, the tool helps to relieve soreness on the background of teething, and also relieves fever during the illness. It should be emphasized that if the patient’s condition does not improve in any way after two days of taking the medicine, and new alarming manifestations are added to the main symptoms, it is imperative to visit a doctor in order to adjust prescriptions.

The method of use of the drug

The instructions for Ibuprofen are detailed.

The most commonly used tablet form of the drug. For children, rectal suppositories or syrup are more suitable. Estimated dosage is calculated individually. Dosage and duration of administration are as follows:

1. In the presence of moderate intensity pain, the medicine is taken at 400 milligrams in three divided doses. The maximum dose is 2.4 grams.
2. Upon receipt of injuries and sprains, 600 milligrams is taken in three divided doses. Dosing reduction is possible provided the patient's condition improves.
3. As part of the complex treatment of rheumatoid arthritis, the following scheme is used: the calculation is based on the data of 30 milligrams of funds per kilogram of patient weight per day.
4. As part of the treatment of ankylosing spondylitis and osteoarthritis, the dosage is adjusted based on 40 to 600 milligrams in three divided doses.
5. Taking pain in the presence of rheumatoid arthritis helps taking a dose of 800 milligrams three times a day.

The instructions for use with Ibuprofen for children indicate that the daily calculation for children from six years of age is as follows: 20 milligrams per kilogram of patient weight. Against the background of any unpleasant symptoms, as well as digestive disorders, stop taking immediately and consult a doctor.

Scheme of using syrup for children:

• for children aged six to twelve months with a body weight of up to 9 kg, the drug is prescribed 2.5 ml three or four times a day;
• for small patients from one year to three years with a body weight of up to 15 kg, the dosage is increased to 5 ml three times a day;
• for children from six to nine years old with a body weight of up to 30 kg, syrup is prescribed in 10 ml three times a day;
• at the age of nine to twelve years, the drug is taken 15 ml three times a day.

Instructions for use of ointment

The dosage is indicated by the doctor individually. The medicinal product is used only externally. Apply a strip of gel (the maximum allowable length is ten centimeters) on the affected area, rub in a circular motion into the affected area until completely absorbed. Wash hands thoroughly with soap and water. It is recommended to perform such manipulations several times a day, the maximum allowable number of times is four per day. The recommended course of treatment is a few weeks. In case of unpleasant symptoms, wash the affected area with soap and water, refuse to use the medicine.

Contraindications

A good therapeutic effect from the drug is far from always justified. In some situations, the use of Ibuprofen tablets is prohibited. Contraindications to taking this medication are:

1. The presence of hypersensitivity to the drug.
2. Peptic ulcer of the stomach or intestines at the stage of exacerbation.
3. Violations of the liver and kidneys.
4. The appearance of dysfunctions of the hematopoietic system.
5. The occurrence of colitis of various nature.
6. Visual impairment.
7. Intolerance to drugs based on aspirin.
8. Heart failure
9. The presence of arterial hypertension.
10. Problems with the vestibular apparatus.

This is described in detail in the instructions for the ibuprofen tablets.

Drug overdose

In cases of overdose, very serious consequences can be observed, exacerbated by existing problems. Against the background of an overdose, the following may occur:

1. The appearance of abdominal pain, vomiting, diarrhea and other digestive disorders.
2. The appearance of disorders of a psychosomatic nature, which will manifest itself in the form of lethargy, increased fatigue, sleep problems and so on.
3. The onset of clinical manifestations of kidney and liver failure.
4. The occurrence of difficulty in breathing. It is possible respiratory arrest.
5. A sharp decrease in pressure.
6. The appearance of disorders of the hematopoietic functions, the occurrence of problems with coagulability.
7. Decreased vision and hearing.

This will confirm the instructions for use. The price of Ibuprofen is not too high.

Other drug compatibility

Despite the fact that the presented drug can more or less well combine with other medical devices, it is necessary to take into account some of its features in the application. Next, consider what drugs Ibuprofen cannot be combined with:

1. Ibuprofen is able to reduce the effect of diuretics.
2. This drug significantly enhances the effects of anticoagulants from the coumarin group. It also enhances hypoglycemic drugs.
3. "Ibuprofen" reduces the hypotensive activity of vasodilators.
4. In the framework of simultaneous administration with antacids, the speed of the absorption process decreases.
5. The enhanced analgesic effect is observed against the background of simultaneous administration with drugs containing caffeine.

This drug does not combine with alcohol, as this increases its toxic effect on the stomach and liver.

Side effects

According to the instructions and reviews for "Ibuprofen", this drug is characterized by normal interaction with medicines from other groups, but nevertheless requires special recommendations. It is important to coordinate with the doctor the use of other painkillers along with antibiotic therapy. In order to eliminate the negative impact on the digestive system, these tablets are taken after meals.

In case of detection of at least one negative symptom arising from Ibuprofen, it is necessary to immediately stop taking this medicine and use an absorbent. If the patient's health is unstable, it is better to contact a hospital medical institution. The following side effects are possible while taking Ibuprofen:

1. The onset of nausea, vomiting, or flatulence.
2. The occurrence of constipation, diarrhea and heartburn.
3. The development of anorexia.
4. The appearance of irritability and headaches.
5. Sleep disorder.
6. The occurrence of allergic skin reactions.
7. Visual impairment.
8. The occurrence of liver and kidney dysfunction.

Among the most severe manifestations, erosive formations in the digestive system are noted, which can lead to the appearance of foci of bleeding. Adverse reactions in the form of bronchospasm or aseptic meningitis are rarely observed. Such conditions require medical attention. Particularly alarming signals are loss of consciousness along with impaired thinking, convulsions and signs of suffocation. Fortunately, such reactions are very rare.

Side effects from the use of syrup: nausea, vomiting, so-called abdominal pains are associated, heartburn, anorexia is characteristic, loose stools, flatulence occur, headache is noted, insomnia, dizziness is possible, hearing loss is possible, tinnitus is also characteristic, excitement as well as drowsiness and depression.

What adverse reactions can the ibuprofen ointment provoke? Instructions for use indicate that in most cases after using its negative reactions are not observed. No overdose has been reported. In some situations, if the drug is used incorrectly or is allergic to the components of the medication, the following side effects can be observed (almost always unpleasant symptoms appear on the 2nd – 3rd day of treatment): nausea, vomiting, decreased appetite, abdominal pain, stomatitis, constipation, pancreatitis (symptoms are noted with accidental use of ointment orally); allergic rashes on the skin, burning sensation at the site of application, numbness, itching, the appearance of red spots (urticaria); sleep disturbances, dizziness, headaches; in some situations, there are violations of the liver and kidneys. In any case, when unpleasant symptoms appear, refuse to use Ibuprofen as an ointment, consult a doctor.

This is confirmed by the instructions for Ibuprofen. The price is indicated below.

Cost

The price of tablets varies between 20-40 rubles, syrup costs about 60-70 rubles, ointment - from 30 rubles. It depends on the region and the pharmacy network.

Similar drugs

The selection of safe analogues must necessarily be agreed with the doctor. As a rule, Ibuprofen does not require replacement, since its cost is affordable and is kept in the region of seventy rubles. Comparing with Nurofen, it is worth emphasizing that Ibuprofen is one and a half times cheaper.

But in the event that for one reason or another there is no opportunity to purchase Ibuprofen, you need to pay attention to the analogues that Arviproks act along with Ibuklin, Arofen, Bolinet, Ibunorm, Ibufen , "Ivalgin", "Caffetine" and so on.

The list of analogues at "Ibuprofen" is quite large, but we should not forget that only the doctor can choose the most suitable drug for this or that person. You can not trust the opinion of a friend, advertising promises and even the advice of a pharmacy seller. The prescription of drugs should always be agreed with the attending physician, who takes into account the individual characteristics of his patient and his concomitant diseases.

What is better to choose instead of "Ibuprofen" for children? The instruction does not contain such information.

What is better "Nurofen" or "Ibuprofen"?

Both of these drugs in the composition have the same active ingredient, and it is contained both there and there in equal proportions. Differences exist only in the content of auxiliary components, as well as in the cost of drugs. As noted in the reviews, "Nurofen" better removes heat, and the analgesic effectiveness of these funds is approximately the same.

We reviewed the detailed instructions for use with Ibuprofen.

Reviews

There are a lot of positive reviews about this drug. For example, people write that this drug perfectly saves from periodic exacerbation of rheumatism. Many people like that Ibuprofen is an affordable medicine, in addition, it is noted that it acts very quickly and always helps.

It is worth noting that in the reviews, people also praise Ibuprofen for its versatility. So, for example, parents often use this tool to help children when their teeth are cut. Women take these pills for painful periods, when the usual medications do not help. Perfectly saves "Ibuprofen" and the appearance of toothache.

Thus, many write that they take Ibuprofen as a family as necessary, and the plate of tablets of this drug is constantly in their medicine cabinet. Ibuprofen is also praised for relieving soreness in the joints. As for the fight against headache, such tablets are eliminated almost immediately.

In addition, it is noted that, despite a considerable number of analogues, consumers still prefer to buy Ibuprofen, as they trust its effectiveness, versatility and speed.

Thus, at present, Ibuprofen is recognized by many as a reliable and proven remedy for heat and pain of various kinds. These pills give a lasting effect, helping to relieve painful symptoms of even the most intense intensity. The article presented instructions for use with Ibuprofen.