In the article, we consider the indications for the use of Venus medicine, instructions for use and reviews on the effectiveness of the drug.
The tool is a venotonic medication that has a pronounced angioprotective effect, reduces the extensibility of the venous walls, increases their tone, reduces the severity of stagnant venous blood, prevents the fragility of capillary vessels, increases their resistance, normalizes lymphatic microcirculation.
Release form
According to the instructions for use, Venarus is made in the form of coated tablets, which are packaged in blisters (15 or 10 pieces in one). Blisters along with instructions for use are placed in cardboard packaging, a total of 60 or 30 tablets in each.
Structure
The main active ingredients of this medication are diosmin and hesperidin, 450 and 50 mg, respectively.
Auxiliary elements of the drug are magnesium stearate, microcrystalline cellulose, sodium starch glycolate, talc and gelatin.
The components that make up the shell are magnesium stearate, sodium lazuryl sulfate, hydroxypropyl methylcellulose, polyethylene glycol 6000, titanium dioxide, yellow and red iron oxides.
Pharmacological properties
As the instructions for use tell us, Venarus is a drug that belongs to the category of venotonics. It has an angioprotective and venotonic effect. Flavonoids - diosmin and hesperidin, which are contained in this medication as the main active elements, reduce extensibility and increase the tone of venous vessels, prevent the occurrence of trophic ulcers, and reduce the severity of the phenomena of blood stagnation. In addition, the drug helps to reduce the fragility and permeability of capillaries, increases their resistance, normalizes the processes of blood microcirculation in small vessels and has a positive effect on the lymphatic flow.
Instructions for use with Venarus tablets describe in detail the pharmacodynamics of the drug.
The active substances of this medication inhibit the production of prostaglandins (substances that take part in the formation of inflammatory processes), due to which they have a pronounced anti-inflammatory effect. Being antioxidants, hesperidin and diosmin neutralize the negative effect of free radicals on the vessels, which eventually leads to the destruction of the cells of the vascular wall and its weakening.
With regular systematic use of this medication, the severity of the clinical symptoms of chronic venous insufficiency of the lower extremities, which have a functional or organic origin, is significantly reduced.
Pharmacokinetics
In accordance with the instructions for use with Venus tablets 1000 mg, this drug is excreted from the body mainly with feces. About 13% of the total amount of medication is excreted in the urine. The half-life is approximately 12 hours. In the body, the drug undergoes a process of active metabolism, as evidenced by the presence of phenolic acids in the urine.
Indications for appointment
The Venus remedy is prescribed for the treatment of the following pathologies: organic or functional venous insufficiency of the entire vascular system, and most often the veins of the lower extremities, which in most cases is accompanied by a feeling of heaviness in the legs, pain, seizures, and the formation of trophic disorders. In addition, this medication can be used to treat hemorrhoids in acute and chronic forms.
Contraindications
As indicated by the instructions for use, Venus is not approved for use in the following pathological or physiological conditions:
- during pregnancy and breastfeeding;
- with excessive susceptibility of the body or individual intolerance to one of the auxiliary or basic elements of the drug.
Dosage and administration
Venus tablets should be taken orally during meals. It is not recommended to grind tablets or chew.
With venous insufficiency, as well as the chronic form of hemorrhoids, the dosage of the drug is 1-2 tablets per day (it is recommended to take it at lunch and in the evening). This is confirmed by the instructions for use with "Venarus" 1000 mg.
In acute hemorrhoids, the recommended dosage for the first four days is 6 tablets per day, and for the next three days - 4 tablets. The total daily dose of the drug is divided into two doses.
The duration of the course of therapy is determined by the specialist individually, depending on the clinical manifestations of a particular disease, its form and severity of symptoms, as well as taking into account the general well-being of the patient. On average, the duration of the treatment course is three months.
Side effects
According to the instructions for use and reviews, Venarus is generally well tolerated by patients. In rare cases, negative side effects may occur. Their list includes:
- from the peripheral and central nervous system - malaise, autonomic lability, dizziness and headaches, convulsive syndrome;
- on the part of the respiratory system - chest pain, a sensation of soreness in the larynx;
- on the part of the digestive system - nausea and vomiting, dyspeptic symptoms, stool disorders (most often diarrhea), colitis, abdominal pain;
- allergic reactions - itching and skin rash, urticaria, allergic dermatitis, Quincke's edema (lips, eyelids, faces).
If the above symptoms occur, it is recommended to stop taking this medication and consult a specialist.
There are no clinical data on the occurrence of signs of drug overdose. The instructions for use with Venarus do not end there.
special instructions
When treating acute forms of hemorrhoids, it is extremely important to take into account such recommendations:
- the appointment of this medication does not cancel and cannot replace other specific methods of therapy (treatment for this pathology should be comprehensive);
- therapy with Venus medicine should not be long;
- with the ineffectiveness of the drug, it is recommended to carry out a proctological examination, and taking into account the results obtained, adjust the therapeutic schemes used.
In the treatment of cases of venous insufficiency, the following measures are recommended to increase the effectiveness of the drug:
- wearing specialized compression underwear (pantyhose, stockings);
- procedures using a cool or contrasting shower for legs;
- adherence to special diets;
- moderate physical activity;
- weight loss (for patients suffering from excess weight);
- the exception of cases of long walking;
- the exclusion of long periods of exposure to sunlight.
All of this is described in detail in the instructions for use with Venarus 500 mg.
Interaction with other medicines
There are no clinical data on the pharmacological interaction of this medication with other medications. It is not recommended to use Venarus during simultaneous therapy with enterosorbents, since its absorption is significantly impaired.
What else can you learn from the instructions for use with Venarus 500 mg?
Prescription during pregnancy and lactation
During clinical trials, teratogenic effects of the drug were not detected, therefore, “Venarus” can be prescribed during pregnancy, but only if necessary.
The use of the drug during breastfeeding is strictly contraindicated, since there is no clinical data on the allocation of its active substances with breast milk.
We examined in detail the instructions for use with Venus 1000 and 500 mg.
Analogues of the drug
The absolute structural analogue of the Venus medicine is a medicine called Detralex. This medicine also has a venotonic and angioprotective effect, reduces the extensibility of the venous walls and eliminates venous congestion, capillary permeability, and increases their resistance. Clinical studies confirm the activity of this drug against venous hemodynamics.
Other medicines that give a similar therapeutic effect are:
- "Sincumar" is an imported drug that is used not only for the treatment of the above pathologies, but also for the prevention of thrombosis, as well as reducing the likelihood of thromboembolic complications due to surgery. This drug should not be taken by people with hemorrhagic diathesis or other pathologies that interfere with proper blood coagulation. In addition, it is not prescribed to patients with renal failure.
- Troxevasin is another imported analogue of Venus medicine. It is prescribed for the elimination of edema, leg pain, in the fight against peripheralitis, thrombophlebitis and other signs of venous insufficiency. In addition, “Troxevasin” favorably manifests itself in the fight against pain and swelling, which were provoked by mechanical injuries. Contraindications here are pregnancy and lactation, a stomach ulcer, gastritis, and kidney diseases.
- “Venolife” is an inexpensive Russian substitute for the “Venarus” medication, which is made in the form of a gel and is prescribed for trophic disorders, edema caused by varicose veins, thrombophlebitis or lymphostasis. In addition, Venolife is used to quickly heal trophic ulcers. The main feature of the medication is that it is very effective for various injuries - dislocations, hematomas and sprains.
- "Venozol" is a domestic analogue, in the form of capsules, which has a wide list of indications. These include swelling, convulsions, varicose veins, cyanosis, varicocele, hemorrhoids. In addition, the drug is prescribed in preparation for or after surgical interventions. The advantage of the tool is its ability to normalize the processes of venous outflow.
- “Venitan forte” is a Swiss-made venotonic medication that is used to eliminate edema resulting from varicose veins, promotes the healing of hematomas and wounds.
We will not consider detailed instructions for use with Venarus analogues, since the pharmacodynamics and contraindications are very similar to the drug considered earlier.
Reviews about the drug
This drug is widely used in clinical medical practice and is considered one of the most popular and effective treatments for a variety of diseases affecting the vascular system of the body.
The patient reviews about the Venus medicine reflect many of the positive properties of this medicine. In particular, they indicate that the medicine effectively helped with developing varicose veins in the very initial stages of its progression. This effect was observed in the fact that, after a course of systemic therapy, patients had pain in the legs, and symptoms of swelling, fatigue and heaviness in the legs decreased. Most often, this remedy was used by women, since this category of patients is most susceptible to venous diseases due to pregnancy and weight gain, which negatively affects the condition of the veins.
Reviews of experts prove that the medication “Venarus” is very effective for thrombophlebitis, varicose veins and helps to strengthen the walls of veins and capillary vessels. Doctors note that they often recommend this drug during pregnancy, as well as with a disease such as hemorrhoids, since the drug significantly removes the symptoms of these pathologies and fights with the main causes of their occurrence - vascular wall weakness, venous congestion, etc.
Despite the large number of positive reviews, some patients observed that the drug did not help them with diseases such as acute hemorrhoids, varicose veins, etc. They note that the medication has a general strengthening effect, helps with prevention, and it does not fits. Most often, according to this group of patients, it is prescribed for complex treatment, for a general effect.
The article presented instructions for use, reviews and analogues of Venus.