It is necessary to treat diseases of the respiratory system with correctly selected drugs that work exactly as necessary in each particular case. For example, a cough associated with an asthmatic attack helps to remove the drug Berotek. Instructions for it, as well as similar medicines and reviews of specialists and patients will be discussed below.
In what form is the medicine issued?
In the pharmacy network, the drug "Berotek" for inhalation can be purchased in two pharmaceutical forms:
- aerosol for inhalation, produced in a bottle with a spray nozzle;
- solution for inhalation.
In what form it is best to purchase and use this drug, the doctor decides with the patient.
What works in the drug?
The composition of the drug “Berotek” is not complicated, because only one active component works in it - phenoterol hydrobromide. In addition to it, various additional components are included in various forms of this medicine. So, in the solution for inhalation by the manufacturers of the drug are included:
- propellant (tetrafluoroethane) used in aerosols as a means of creating high pressure in the cylinder;
- citric anhydride - an aerosol component that gives a feeling of freshness;
- ethanol is a monohydric alcohol used in medical aerosols as an antifoam agent with antibacterial properties;
- distilled water, in the amount necessary to create a certain concentration of the drug.
As part of the 0.1% solution for inhalation "Berotek" as an auxiliary substance, the manufacturer uses:
- benzalkonium chloride, which has the properties of a local antiseptic;
- disodium edetate dihydrate - a forming component;
- sodium chloride - isotonic solution with rehydrating and detoxifying properties;
- 1 n hydrochloric acid, contributing to the death of pathogens;
- disodium edetate dihydrate - a substance that does not allow the formation of a precipitate in a solution;
- distilled water to form a solution.
How does the drug work?
Many people suffering from diseases associated with spasm of the bronchi, for example, bronchial asthma, and forced to constantly use drugs to stop coughing, shortness of breath or hypoxia, ask the question: "Berotek" is a hormonal drug or not? "The answer to this question is simple - in There is no hormone-containing substance in this medicine. "But how does it work in this case?" is the next reasonable question, because quite often the drugs that help stop such problems contain hormones. As part of this drug, which It is produced either in the form of a ready-made aerosol, or in the form of drops for the preparation of an inhalation solution, and only one active component, phenoterol hydrobromide, works. According to its pharmacological activity, this substance belongs to the group of tocolytics and adrenomimetics. The work of all systems of the human body is very complex, dependent on the interaction a large number of different structures, for example, the respiratory system contains structures such as bronchioles - the final branches of the so-called bronchial tree. And in their smooth muscles, beta 2 -adrenoreceptors work - a subtype of receptors that are sensitive to the main hormone of the adrenal glands - adrenaline.
Phenoterol hydrobromide is an adrenaline agonist and, like the hormone itself, causes the relaxation of beta 2 -adrenoreceptors of the smooth muscles of bronchioles in particular.
This serves as a way to counter the immediate bronchospastic hypersensitivity reactions that occur in response to the action of allergens, cold air, histamine, and other irritants. This substance does not allow the development of such a clinical symptom as bronchial obstruction. If it enters the body at higher doses, then there is an increase in mucolytic clearance - a non-specific protective mechanism of the respiratory system. Fenoterol is also able to suppress the tone and contractile activity of the uterine myometrium.
The pathway of the drug in the body
The medicine "Berotek" can be purchased both in the form of a ready-made aerosol, and in the form of a liquid for the preparation of an inhalation solution. Such pharmacological forms are not accidental - the tool is used only in the form of inhalations, and the inhalation systems themselves can be different. When in the form of an aerosol mixture in the upper respiratory tract of the total amount of the active component, only 10-30% penetrate deeper and reach the lower parts of the respiratory system. The remaining amount of the drug is deposited and swallowed by the patient, entering the gastrointestinal tract. For the drug "Berotek" instructions for use indicate a two-phase absorption of the active substance. 30% of the digestible amount is rapidly absorbed and rapidly excreted - the half-life from the body is 11 minutes. 70% of the working Phenterol is absorbed slowly, and the half-life of this amount from the patient's body will be 120 minutes. The drug "Berotek" (aerosol or inhalation based on drops) metabolizes mainly in the liver, turning in the intestine under the influence of bile into sulfate conjugates that do not have pharmacological activity.
What diseases is the drug prescribed for?
Is Berotek prescribed for coughing? This symptom helps to remove this drug only if it is based on bronchospasm of various etiologies, an inflammatory cough is not treated with this medicine. Berotek is prescribed for use in the following cases:
- bronchospasm caused by an asthmatic attack;
- narrowing of the airways of a reversible nature;
- chronic obstructive pulmonary disease (COPD);
- chronic obstructive bronchitis;
- emphysema.
Also, this drug helps to prevent and relieve seizures in the so-called asthma of physical effort, when even a slight stress of physical forces can cause a sharp exacerbation of the disease.
In what cases can I not take the medicine?
Many patients with a diagnosis of respiratory dysfunction are prescribed Berotek inhalation. Instructions for use indicate not only the health problems that it helps to solve, but also contraindications for use. This is a fairly extensive list that must be considered when prescribing inhalation therapy:
- aortic stenosis;
- glaucoma;
- individual intolerance (hereditary or acquired) of biologically active components of the drug;
- hypertrophic obstructive cardiomyopathy;
- hypersensitivity to both the main active component and additional substances;
- heart defects of various kinds;
- tachycardia;
- thyrotoxicosis;
- uncompensated type diabetes.
It has been proven in numerous scientific studies that this drug passes through the placenta and into breast milk, so it is forbidden to take it during pregnancy, a strict ban applies to the first trimester, and during breastfeeding. Experts allow in case of emergency the use of Berotek inhalations in the 2nd and 3rd trimester of pregnancy. If the question of such therapy is during lactation, then before starting treatment, the issue of breastfeeding should be resolved by transferring the child to artificial feeding. Also, this drug is not prescribed for children under the age of 4 years.
Under control
As with any other medicinal product, for Berotek, the instructions for use contain important information necessary for familiarization. This product is approved for use only under regular medical and diagnostic monitoring in the following cases:
- arterial hypertension having an uncontrolled form;
- hyperthyroidism;
- a history of myocardial infarction;
- compensated diabetes mellitus;
- severe diseases of the cardiovascular system;
- pheochromocytoma.
How to take medicine in the form of an aerosol?
Talks about the drug "Berotek" instructions for use. It indicates the dosage regimen of the drug, the intensity of the therapy conducted with its help. But in no case should you take it without appointing a treating specialist. Only a doctor who knows the history and course of the patient’s disease will be able to choose an adequate medication and the mode of its use.
The method of the treatment procedure depends on the form of the drug - the aerosol is directly sprayed into the oral cavity, observing the following algorithm of actions:
- Shake the bottle thoroughly so that the active component is evenly distributed in the drug solution;
- remove the protective cap;
- turn the bottle upside down;
- double-click on the bottom of the cylinder so that the injection of the drug is complete;
- take a deep breath and exhale;
- grip the tip of the sprayer with your lips so that the bottom of the spray can is directed vertically upward;
- simultaneously press the bottom of the container and inhale deeply;
- hold your breath to allow the drug to penetrate deep into the body;
- if the doctor is prescribed to make two injections to increase the dose of the drug, then you should again take a deep breath and exhale, spray on the next breath and hold your breath;
- close the cylinder with a protective cap, turning it over to its normal position.
Inhalation treatment
If the drug "Berotek" is used in the form of a liquid for the preparation of an inhalation solution, then the following recommendations should be followed:
- It is possible to dissolve the inhalation agent only in physiological saline, distilled water cannot be used for these purposes.
- The required number of drops of the drug is diluted in saline to a volume of 3-4 ml.
- The procedure is carried out using special equipment - a nebulizer or some other device that ensures the optimal speed of medicinal air flow.
- For the treatment of children under the age of 6 years, if the body weight of the child is less than 22 kilograms, use 0.05 ml of the drug, which is equal to 1 drop of solution, per 1 kg of body weight 3 times a day. For such children, the highest daily dose of the drug should not exceed 30 drops or 1.5 ml.
- Patients aged 6 to 12 years old, if the child’s body weight is in the range of 22 to 36 kilograms, undergo treatment with Berotek at the rate of 0.25-0.5 ml in a single dose, which can be taken 4 times a day. If a therapeutic need arises, then a single dosage may be increased, and only the doctor observing the child can resolve this issue.
- Children over 12 years old, as well as adult patients up to 75 years of age, traditionally use 4 times the use of inhalation per day with a single dose size of 0.5 ml. The specialist leading the patient can change this parameter both in the direction of increasing and decreasing the single dose of the drug for inhalation.
How is an overdose manifested?
Using the Berotek drug for inhalation, the patient should remember that the number of procedures per day is strictly adhered to and that the dosage of the drug is accurate for each procedure. If you neglect the doctor’s recommendations, you can disrupt the treatment regimen and get an overdose of the drug. It manifests itself with symptoms such as:
- anginal pain;
- hyperemia of the face and upper body;
- hypertension or hypotension (depending on the patient's predisposition);
- arrhythmia;
- palpitations
- angina attacks;
- tachycardia;
- intentional tremor;
- increase in pulse pressure.
The active component of Berotek phenoterol hydrobromide does not have a specific antidote. For stopping an overdose, antagonist substances belonging to the group of cardioselective beta-blockers are used. But their use requires special care in selecting the dose, as they can provoke activation of bronchial obstruction. It is imperative that the side effects of this medication use symptomatic therapy, and in some cases, intensive methods of maintaining vital functions are used.
Possible side effects of the drug
A drug such as Berotek may have a side effect that must be considered and monitored during treatment. In this capacity, the following may appear:
- headache;
- dizziness;
- cough;
- myalgia;
- nervousness;
- vomiting
- palpitations
- weakness;
- rash;
- tachycardia;
- nausea;
- hand tremor.
The manifestation of such an action of the drug can be quite strong, then either a dose adjustment or complete cancellation and selection of another drug will be required.
Some features of treatment
The drug "Berotek", a solution for inhalation or aerosol, requires the patient who is shown to use it to comply with the doctor's recommendations on dosage and mode of use. The drug can be used in complex treatment, which should be carried out in a hospital under the constant supervision of specialists. The tastes of the aerosol and the solution for inhalation differ from each other, although the healing qualities and organoleptic properties are unchanged in both forms.
Drug Interactions
Many patients who use Berotek (drops or aerosol) in their treatment have to combine several medications. In this case, their interaction should be taken into account. So, substances contained in anticholinergics, tricyclic antidepressants, in MAO preparations (monoamine oxidase enzyme inhibitors, as well as beta-adrenoreceptor agonists. Increased the potential for side effects, the combined use of Beroxerin and , as well as beta-adrenomentics.This drug enhances the effect on the cardiovascular system of halogenated hydrocarbon antiseptics ov.
Where to buy and how to store?
One of the questions that patients ask the doctor when prescribing Berotek is the price. The average drug cost in pharmacies is about 300-500 rubles, depending on the form of release. You can buy it only with a prescription from your doctor. The drug, in whatever form it is released, must in no case be frozen. Store the bottle with drops or aerosol at room temperature, without exposure to direct sunlight and high temperature access, which is especially true for the aerosol in the bottle under pressure. Storage conditions stipulates for the preparation "Berotek" instructions for use.
Are there any analogues?
Many patients who are constantly forced to use drugs to stop asthma attacks are wondering if there are similar drugs for Berotek. Yes, there are such medicines and they can be purchased at the pharmacy network on prescription. Synonyms for this medication are Fenoterol Hydrobromide and Fenoterol, which can also be considered as Berotek generics. Another drug that can be purchased in pharmacies that works on the same active ingredient is Partusisen. A two-component drug that works in the same way as the drug in question - "Berodual", produced in the form of a solution for inhalation and in the form of an aerosol. As with Berotek, the instructions for use for all of these drugs describe their principle of action and conditions of use.
Respiratory diseases, manifested in attacks of suffocation, force patients to use special drugs that stop this manifestation of the disease. One of the drugs demanded is the Berotek medication. The price makes it affordable for all patients in need of such a medicine. And the reviews that both specialists and patients leave about him indicate its effectiveness.