In cases of gastrointestinal motility, doctors prescribe drugs based on trimebutin maleate. These drugs have few contraindications and rarely cause unpleasant side effects. Such drugs literally in half an hour eliminate cramping and abdominal pain. At the same time, they normalize muscle tone not only in the intestine, but also in the stomach and esophagus.
Composition and effect of drugs
The active component of the drug is trimebutin maleate. It affects the formation of amino acid residues and regulates gastrointestinal motility. With spastic phenomena in the intestines, stomach or esophagus, trimebutin relaxes the muscles of the internal organs. If there is a decrease in the tone of the digestive system, then the drug stimulates peristalsis and promotes emptying.
The therapeutic effect occurs quite quickly. 30 minutes after taking the medicine, the abdominal pain disappears and the cramps disappear. In this case, trimebutin only affects the smooth muscles of the digestive tract, but does not affect the central nervous system.
The medicine is produced in various forms:
- Tablets. Each of them contains 100 mg of the active ingredient.
- Powder in vials. This form is intended for the preparation of a suspension. It is taken orally or rectally (through an enema). 5 ml of the suspension contains 24 mg of the drug substance, and in one bottle of powder - 1.2 g.
- Solution in ampoules. Each ampoule contains 50 mg of trimebutin. This form of medication is for intramuscular and intravenous injections.
Indications and contraindications
Instructions for use of trimebutin maleate recommends that this remedy be prescribed for the following diseases and conditions:
- dyspeptic phenomena associated with impaired peristalsis;
- pathologies of the stomach and duodenum;
- abdominal pain due to cramping;
- flatulence;
- impaired bowel function due to dystrophic changes;
- reflux of gastric contents into the esophagus (reflux).
Also, this tool is used before x-ray and endoscopic examination of the digestive tract.
This medicine is relatively harmless. It has few contraindications. The drug should not be used by people who are allergic to trimebutin maleate. Children can take this tool over the age of 3 years.
During pregnancy, the drug can be used only in the second and third trimesters. In the early stages, this medicine is contraindicated. During lactation, you need to refuse to take the medication.
Unwanted effects
Usually, taking the drug is not accompanied by any unpleasant sensations. However, the instruction of trimebutin maleate warns of the possible development of allergies during the course of treatment. Such manifestations indicate an increased sensitivity of the patient to trimebutine. In this case, the drug should be discontinued.
With the introduction of the drug into the vein, some patients experienced fainting. In case of loss of consciousness, the patient must be given first aid. In such cases, the patient is transferred to other forms of the drug (in the form of tablets or suspensions).
Mode of application
The dosage of the medicine is selected by the doctor individually for each patient. On average, the following doses are prescribed:
- orally: up to 300 mg per day;
- rectally: 0.1-0.2 g of the active ingredient per day;
- intravenously or intramuscularly: 1 ampoule (50 mg) per day;
- children (in tablet form): 25-50 mg three times a day.
Storage, price and analogues
Powder, tablets and ampoules are stored at a temperature of no more than +25 degrees. They can be used for 1.5 years. The prepared suspension can be stored for no more than 1 month.
A prescription for the purchase of this drug is not required. However, this does not mean that the cure for spasms can be taken independently. Only a doctor can decide on the advisability of using this medication.
As for the price of the drug, it depends on the manufacturer. After all, trimebutin maleate is the name of a medicinal substance. And medicines with the content of this component can be issued under different brand names:
- Neobutin
- "Neobutin Retard";
- "Trimedat."
All these drugs have the same composition. They are structural analogues of trimebutin maleate.
The price of the drug "Neobutin" is 360-400 rubles. Somewhat more expensive is its prolonged form "Neobutin retard" (from 400 to 450 rubles).
The cost of the drug "Trimedat" varies from 260 to 530 rubles, depending on the form of release.
Reviews
You can find a lot of positive reviews about drugs based on trimebutin. Patients consider these drugs effective antispasmodics. After a course of treatment, abdominal pain, flatulence, and a feeling of heaviness in the stomach disappeared in patients. The drug normalizes stool and helps to get rid of constipation and diarrhea for a long time.
In some patients, after taking antispasmodics, a slight dizziness occurs. However, when taking medications with trimebutine, there were no unpleasant sensations. The cost of these drugs is quite high, however, many patients prefer to take just such antispasmodics.
Patients note that fake antispasmodics with trimebutin are often found. They have no therapeutic effect. Therefore, the medicine must be purchased only in reliable and trusted pharmacy chains.