With high blood pressure, doctors recommend taking the drug "Tenox". Instructions for use of this medication reports that it helps not only with hypertension, but also with some forms of angina pectoris. According to experts, this tool has a mild effect. It does not cause a sharp drop in blood pressure. The drug is prescribed as monotherapy, and with high pressure and ischemia - in combination with other medicines.
The composition of the drug
The active ingredient in Tenox is amlodipine. The medicine is released in the form of tablets. They contain 5 or 10 mg of active ingredient. Tablets are white, rounded with a beveled edge and a notch.
The composition of the drug includes auxiliary ingredients: cellulose, starch, magnesium and silicon compounds. They contribute to better absorption of the active substance.
The effect of tablets on the body
There are special proteins in the cell membranes that regulate calcium intake. This element causes contraction of the muscles of the vessels and their narrowing. Such proteins are called calcium channels.
When ingested, amlodipine binds to receptors and blocks calcium channels. As a result, vasodilation occurs and blood pressure decreases. In this case, the drug acts not only on peripheral vessels, but also on coronary vessels. This reduces cardiac ischemia and helps eliminate pain during an attack of angina pectoris. This action allows the patient to reduce the dosage of Nitroglycerin. Pressure decreases smoothly and gradually. The heart rate does not increase.
The effect of the drug begins 2-4 hours after administration. The effect lasts about a day. The digestibility of the drug is independent of food intake. Blood pressure becomes stable after about 7 days of taking the pill regularly.
Indications
Indication for the use of the drug "Tenox" is arterial hypertension. This medicine can be used as the only remedy for lowering blood pressure, as well as with other medicines.
The drug is also used for stable angina pectoris of vasospastic etiology. If ischemia is caused by a sudden spasm of the coronary vessels, then Tenox will help them relax and thereby relieve pain behind the sternum. This kind of disease is called Prinzmetal angina.
Contraindications
Not all patients can take Tenox. A contraindication to the prescription of the drug may be the presence of the following conditions and diseases:
- Intolerance to amlodipine and auxiliary components.
- Low pressure.
- Some heart diseases: aortic stenosis, chronic heart failure, cardiogenic shock. In addition, the drug can not be taken within a month after a heart attack.
- Severe impaired renal function.
- Children's age (up to 18 years).
- Pregnancy and lactation.
With caution, Tenox pressure pills are prescribed for elderly patients with diabetes, with bradycardia, arrhythmias and impaired liver function. According to the instructions, in all these cases, a reduced dosage of the drug and constant medical monitoring of the human condition are required.
Unwanted effects
According to reviews, while taking "Tenox" side effects are noted in the first days of admission. The patient may be disturbed by weakness, dizziness, fatigue, drowsiness. These are signs of a decrease in blood pressure. Typically, the body quickly adapts to this condition. However, if the patient's pressure drops below normal, then it is necessary to reduce the dose of the drug.
Instructions for use "Tenox" reports that other undesirable effects are possible:
- swelling of the legs;
- arrhythmia;
- dyspnea;
- dyspeptic symptoms (nausea, abdominal pain, constipation or diarrhea);
- signs of skin allergy;
- joint and muscle pain;
- frequent urination (especially at night);
- dry mouth.
Manifestations from the gastrointestinal tract usually go away on their own and do not require drug withdrawal. With arrhythmia, a replacement of the drug is necessary. If the patient has dry mouth, this may indicate poor tolerance of the medication.
With leg edema, an additional diuretic is indicated. If the patient has an allergy, then the drug must be replaced with a product with a similar effect, but with a different composition.
According to the instructions, with an overdose of Tenox tablets, blood pressure in patients is greatly reduced. This is accompanied by severe tachycardia, dizziness, weakness and loss of strength. In severe cases, collapse may occur. With such phenomena, it is necessary to rinse the patient’s stomach, give enterosorbent and urgently call a doctor. Treatment is being carried out aimed at maintaining the work of the heart. The patient is given vasoconstrictors and calcium gluconate.
How to take medicine
How to take Tenox? The dosage regimen and the dosage are selected by the doctor depending on the condition of the patient. Usually, treatment begins with 5 mg of the drug per day, then the dose is increased to 10 mg.
If maintenance therapy of high pressure is performed, then 2.5 to 5 mg per day is prescribed. In the treatment of angina pectoris, 5-10 mg of the drug is taken per day.
Elderly people and patients with liver pathologies are recommended to take 2.5 mg of the drug per day for hypertension. If treatment or prevention of angina attacks is carried out, then a dose of 5 mg is allowed. The same amounts of the drug are prescribed for patients with low stature and small body weight.
special instructions
Instructions for use "Tenox" recommends a diet with a sodium restriction during the treatment period. It is also necessary to monitor the body weight of patients. The condition of the teeth during the treatment period may worsen due to calcium deficiency. Therefore, you need to pay special attention to oral hygiene and regularly visit the dentist.
It is believed that this drug does not have withdrawal syndrome. However, after completing the course of treatment, doctors reduce the dosage of the drug gradually.
In many patients, drowsiness, dizziness and fatigue due to a decrease in blood pressure may occur in the early days of therapy. Therefore, driving a car and doing complex work at this time is not recommended.
Interaction with other drugs
Instructions for use "Tenox" reports that the drug may interact with other medicines. Therefore, it is necessary to warn the doctor about taking medication.
It is not recommended to prescribe the drug in conjunction with the following agents:
- Non-steroidal anti-inflammatory drugs, drugs with calcium, estrogens and sympathomimetics. These medicines weaken the hypotensive effect of the tablets on pressure.
- Medications containing lithium. In this case, the toxic effect on the central nervous system is enhanced. This is expressed in noise in the ears, nausea, tremors and impaired coordination of movements.
- "Procainamide" and "quinidine." Their combined use with Tenox can lead to abnormalities on the ECG (lengthening of the QT interval).
- Antioxidants. This can increase the side effects of the drug from pressure.
Neuroleptics, Verapamil, alpha and beta-blockers, ACE inhibitors enhance the hypotensive effect. Their joint administration with Tenox is not prohibited, but care must be taken to ensure that the pressure does not fall below normal.
How to store medicine
Tablets should be stored at a temperature of no more than +30 degrees. They remain valid for 4 years. After this period, the medicine should not be used. The pill box should be kept out of reach of children to prevent accidental poisoning.
Price and analogues
The price of the drug in pharmacies is from 55 to 650 rubles. It depends on the dosage of the drug and the number of tablets in the package.
You can choose analogues of "Tenox" for the active substance. These include:
- Amlodipine;
- Norvask
- Agen
- Azomex
They have the same effect on the body, since their active component is the same. The cheapest drug is Amlodipine. Its price is from 50 to 280 rubles. "Agen" and "Azomex" cost from 250 to 480 rubles. The most expensive medicine is Norvask; its price is from 300 to 1000 rubles.
Some people are allergic to amlodipine. In some patients, taking calcium channel blockers does not lead to a decrease in pressure. In this case, it is necessary to select funds from the group of ACE inhibitors. These drugs also have a hypotensive effect. In some cases, they are supplemented with diuretics. However, only a specialist can select similar drugs for pressure with a different composition.
The opinion of doctors
Doctors have a positive opinion about Tenox. They believe that this drug reduces blood pressure well and retains the effect for a long time. In this case, blood pressure indicators do not fall below normal. The medicine acts mildly and does not lead to persistent hypotension.
Doctors recommend taking this medication in the evening. This protects against attacks of nighttime hypertension. This is a rather old drug, it belongs to the second generation of calcium channel blockers. Its action is well studied and known to doctors.
Doctors attribute its drawbacks to its ability to cause leg swelling in some patients. It is noteworthy that such a side effect is not eliminated with a decrease in dose. Because of this, patients refuse the drug. Some experts prescribe ACE inhibitors with Tenox. Such a comprehensive treatment reduces swelling.
Doctors warn that taking medication for pressure alone is unacceptable. This drug requires careful adherence to a dosage that can only be determined by a specialist. Self-medication can lead to an excessive drop in blood pressure.
Positive reviews
You can find many positive reviews about the "Tenox" from patients. This drug helped them to quickly lower their pressure and keep it at the proper level. Many patients, taking this medicine, were able to relieve the symptoms of hypertension, which bothered them for many years.
Often "Tenox" reduces blood pressure more effectively than other drugs. Patients report that they tried many other drugs for pressure, but there was no tangible and long-term effect. And only “Tenox” helped them maintain a stable normal pressure.
There are positive reviews from patients with angina pectoris. According to them, this medicine helped them relieve heart pain. Using Tenox allowed them to reduce the dosage of other drugs and reduce the burden on the digestive tract and liver. Some patients, on the recommendation of a doctor, take this medication to prevent angina pectoris. This helps them prevent an impending heartache attack.
Negative reviews
Negative reviews about this medicine are associated with its side effects. Many patients had swelling on their feet during the course of treatment. The instruction warns of the likelihood of such a phenomenon. Usually, edema due to fluid retention in the body is noted after 7 days of using Tenox. This side effect is characteristic of many drugs from the group of calcium channel blockers. In these cases, you should consult your doctor about the simultaneous appointment of diuretics or replacing the drug with a more suitable one.
There are reports of diarrhea and nausea after taking the drug. Dyspeptic symptoms are possible in the first days of taking the medicine. Usually they pass quickly and do not require special treatment.
Many reviews report dizziness and drowsiness from the drug. These side effects are natural, since a decrease in pressure is often accompanied by such manifestations. However, if the unpleasant symptoms are too pronounced or do not disappear for a long time, then you need to see a doctor and discuss the possibility of replacing the medicine. Often an excessive feeling of fatigue and dizziness are noted when the recommended dose is exceeded.
Sometimes there are reports of circulatory disorders during the course of treatment. This is expressed in numbness of the extremities and blueness of certain parts of the body. Such a side effect is not indicated in the instructions for use. It is possible that it is associated with already existing vascular disorders in the patient. It may also be the result of an increased sensitivity of the body to amlodipine. In this case, consult a doctor. Usually, all side effects of Tenox are reversible and disappear after its cancellation.