For many vascular and metabolic disorders, doctors prescribe Actovegin. Instructions for use of this drug indicate that it is also prescribed for the healing of burns, wounds, radiation injuries, etc.
This drug activates tissue metabolism, improves trophism, and stimulates regeneration. Its active substance is deproteinized hemoderivative, which is obtained from calf blood. It contains low molecular weight peptides and nucleic acid derivatives.
The use of the drug "Actovegin" leads to increased utilization within the cells, to an increase in the energy resource in them, to an acceleration of cellular metabolism. The instructions for use clearly indicate that this drug effectively affects the healing and regeneration of the skin in cases where increased energy consumption is needed. This drug is also used for hypoxia, ischemia of various tissues and organs, lack of substrate, because Actovegin helps stimulate the energy processes of anabolism and metabolism (functional). In addition, it enhances blood supply.
If the metabolism and blood supply to the brain are disturbed (traumatic brain injuries; ischemic stroke; cerebral insufficiency syndrome, etc.), if glucose transmission through the BBB and its cellular utilization have worsened, actovegin may be prescribed by the doctor. Its use in this case will lead to the normalization of these indicators, improved transport and utilization of glucose, and oxygen consumption will also increase. In the same way, this drug acts in case of arterial angiopathy, ulcerative lesions of the lower extremities. That is why actovegin (instructions for use clearly indicates this) is prescribed by the doctor when significant peripheral (venous or arterial) circulatory disorders occur.
This medicine is used when it is necessary to accelerate the healing of wounds of various etiologies: radiation injuries (mucous membranes, skin, nerve tissues), trophic disorders (for example, bedsores), burns (thermal, chemical), etc. At the same time, actovegin (indications for use clearly indicate this) helps to improve granulation, that is, the level of hydroxyproline and hemoglobin increases, the concentration of DNA increases, and morphological and biochemical parameters improve. This drug is prescribed and, if necessary, secondary healing of the skin. Actovegin is used, instructions for use give a link to this, and with skin transplantation.
Since the active substances of actovegin are physiological ingredients that are usually found in the body, it has practically no contraindications, except for hypersensitivity to the drug. Even elderly patients, infants up to a year old, patients with hepatic, renal failure, pregnant and lactating are prescribed this drug, if there are indications for it. The only side effect of Actovegin, and even that is extremely rare, may be an allergic reaction. It can manifest itself in fever, hives, swelling, increased sweating, a feeling of heat.
The dosage and method of use of the drug "Actovegin" (instructions for use contain such information) depends on the severity of the course of the disease and its form. Dragees are usually prescribed to take 1-2 times a day three times. before eating. It does not need to be chewed, but simply should be washed down with water (a small amount).
Actovegin doctor can prescribe both intravenously and intramuscularly. Also, this drug can be administered drip or stream, but all these types of administration are carried out strictly under the supervision of medical professionals. The dosage is different depending on the form of the course of the disease.
The effect of this drug is visible already thirty minutes after its administration parenterally or after internal administration, and it reaches a maximum after about three hours.