Surely everyone is familiar with the symptoms of colds and flu. Unfortunately, many people take this disease lightly. Experts say that with improper and untimely treatment of such conditions, the patient may experience serious complications. Therefore, at the first signs of the disease, you should immediately consult a doctor.
Modern pharmaceutical companies produce a huge number of different drugs against flu and colds. One of the most popular is the medication "Antigrippin-Anvi." Instructions for use, photos of the medicine will be presented in the article.
Release form, composition, packaging and description
The drug "Antigrippin-Anvi", the instruction of which is enclosed in a cardboard package, is made in the form of capsules. They can be of two types:
- Capsules A have a green color and a special hardness. Their contents are a mixture of crystalline and amorphous masses of light yellow color (may have a green tint). The presence of lumps is also possible.
- Capsules B are white. Their contents are small granules or white powder with a yellowish tint and with the presence of lumps.
Such a drug goes on sale in contour packaging (10 capsules A in one and 10 capsules B in another).
What ingredients does Antigrippin-Anvi contain? Instructions for use informs that capsule A contains ascorbic acid, acetylsalicylic acid and rutoside in the form of trihydrate. As additional components use potato starch and calcium stearate.
As for the gelatin shell, it consists of the dye azorubine, dye yellow quinoline, dye black diamond, dye patented blue or blue diamond, gelatin and titanium dioxide.
Capsules B contain calcium gluconate monohydrate, diphenhydramine hydrochloride and sodium metamizole monohydrate. Excipients of this medication are potato starch and calcium stearate. The composition of the shell includes gelatin and titanium dioxide.
It should also be noted that there are other forms of the drug "Antigrippin-Anvi." Instructions for use (effervescent tablets will be described later) reports that the active ingredients of this medication are chlorpheniramine maleate, paracetamol and ascorbic acid.
Pharmacological properties
What is the medicine "Antigrippin-Anvi"? Instructions for use indicate that it is an antipyretic, angioprotective, analgesic, anti-inflammatory and antihistamine drug. Its effectiveness is due to the presence of several active components.
Ascorbic acid is able to regulate redox processes, carbohydrate metabolism, tissue regeneration and blood coagulation, as well as increase the body's resistance.
Acetylsalicylic acid, or aspirin, has an antipyretic, anti-inflammatory, analgesic and antiplatelet effect.
Rutoside is a powerful angioprotector. It eliminates the symptoms of inflammation, reduces capillary permeability, increases deformity and weakens red blood cell aggregation, and stabilizes vascular walls.
Diphenhydramine has an anti-allergic and decongestant effect. Also, this substance reduces vascular permeability, eliminates hypersensitivity reactions from the respiratory system, swelling and hyperemia of the nasal mucosa.
Metamizole sodium has a slight anti-inflammatory, antipyretic and analgesic effect, which is associated with inhibition of the biological synthesis of prostaglandins.
Calcium gluconate is able to regulate the exchange of calcium and phosphorus. This ingredient has an antiallergic effect and also reduces vascular permeability. In the treatment of allergic diseases, it is recommended to take it with antihistamines.
Indications
What diseases can a patient be prescribed with the Antigrippin-Anvi medication? Instructions for use (in capsules, this tool is recommended only for adults and adolescents from 15 years old) indicates that the drug in question is intended for the symptomatic treatment of influenza, acute viral diseases and colds.
Contraindications
Are there any contraindications for Antigrippin-Anvi? Instructions for use, reviews indicate that such a medicine can not be prescribed under the following conditions:
- bleeding from the digestive tract;
- tendency to bleeding;
- bronchial asthma and diseases accompanied by bronchospasm;
- pronounced changes in the work of the liver or kidneys;
- hereditary hemolytic anemia (including anemia caused by glucose-6-phosphate dehydrogenase deficiency);
- erosive and ulcerative changes in the digestive tract;
- hemorrhagic diathesis (for example, with thrombocytopenic purpura, hemophilia, hypoprothrombinemia, thrombocytopenia, telangiectasia, von Willebrand disease);
- portal hypertension;
- suppression of hematopoiesis (agranulocytosis, neutropenia, leukopenia);
- calcium nephrolithiasis;
- stratified aortic aneurysm;
- hypercalcemia, hypercalciuria;
- sarcoidosis;
- lack of vitamin K;
- an overdose of cardiac glycosides;
- pregnancy and lactation;
- under the age of 15 years;
- glucose-6-phosphate dehydrogenase deficiency;
- hypersensitivity to the substances of the drug.
It should also be noted that the Antigrippin-Anvi medication, the instruction of which is described below, is prescribed with special caution to people with gout, hyperuricemia, urate nephrolithiasis, peptic ulcer and insufficiency (decompensated) cardiac activity.
Capsules "Antigrippin-Anvi": instructions for use
Antigrippin-Anvi capsules are administered orally two at a time (one capsule B and one capsule A). The medication is taken after eating twice or thrice a day.
The treatment time with this tool is 3-5 days. In the absence of the desired result, the medication should be stopped and consult a doctor.
Antigrippin-Anvi effervescent tablets: instruction
The mentioned form of the drug is also used internally. The maximum therapeutic effect is achieved when taking the medicine 30 minutes before or 2 hours after eating.
Before taking, effervescent tablets must be dissolved in 200 ml of warm water. The finished solution is immediately drunk. Its storage is unacceptable.
The duration of therapy and the dosage of this medicine are calculated individually.
Adolescents from 15 years of age are shown taking 1 tablet of the drug 2-3 times a day. The minimum interval between the use of the medication is 4 hours. No more than three tablets should be taken per day.
The duration of treatment with the drug in question is usually 3-5 days.
With kidney or liver failure, as well as over the age of 60 years, the interval between taking the medicine should be 8 hours.
Side effects
What negative reactions does the Antigrippin-Anvi medication cause? Instructions for use indicate the following side effects:
- gastralgia, bleeding, anorexia, vomiting, diarrhea, liver failure, erosive-ulcerative changes and nausea;
- kidney failure;
- tachycardia and increased pressure;
- rash, angioedema, and bronchospasm.
What adverse reactions occur with prolonged use of the drug "Antigrippin-Anvi"? The instruction (capsules and effervescent tablets cause the same adverse effects) indicates the following effects:
- headache, anuria, and dizziness;
- vision damage, tinnitus;
- bronchospasm;
- weakening of platelet aggregation, hypocoagulation and hemorrhagic syndrome;
- leukopenia, impaired renal function, thrombocytopenia, vomiting and agranulocytosis;
- development of anaphylactic shock, deafness, Stevens-Johnson syndrome, Lyell's syndrome;
- papillary necrosis of the kidneys, interstitial nephritis, proteinuria, oliguria, staining of urine in red;
- the development of Reye syndrome in children (hyperpyrexia, metabolic acidosis, liver damage, changes in the psyche).
Overdose cases
Instructions for use "Antigrippin-Anvi" reports that with an overdose of this drug, the patient may experience the following symptoms:
- vomiting, sweating, nausea, and pallor of the skin;
- stomach pain and tachycardia;
- ringing in the ears (with a weak overdose);
- bleeding, collapse, convulsions, drowsiness, shortness of breath, anuria, bronchospasm, progressive respiratory paralysis (with severe overdose).
To treat such conditions, gastric lavage is performed, activated charcoal and saline laxatives are used. In convulsions, it is recommended to administer Diazepam intravenously.
Interaction with other medicines
At the same time taking the drug with "Spironolactone", "Furosemide", antihypertensive and uricosuric agents, their effectiveness is significantly worsened.
When combined with heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic agents, their effect is enhanced.
With the simultaneous use of the drug with Zidovudine, barbiturates, Rifampicin, alcohol-containing drugs and antiepileptic drugs, the risk of hepatotoxicity increases.
Ascorbic acid is able to enhance the absorption of iron preparations in the intestine.
It should also be noted that the instructions for use of Antigrippin-Anvi indicate that this drug enhances the side effects of glucocorticosteroids, non-opioid analgesics, sulfonylureas and methotrexate derivatives, as well as NSAIDs.
Sedatives and tranquilizers stimulate the analgesic effect of the medication in question.
Special recommendations
What should a patient know before using the Antigrippin-Anvi medication? Instructions for use (tablets and capsules should be used only when indicated) states that with prolonged use of the drug, a peripheral blood test should be performed, as well as monitoring the liver.
Acetylsalicylic acid in small doses can reduce the evacuation of uric acid. This fact can lead to exacerbation of gout.
During treatment with this remedy, patients need to exclude the use of alcohol-containing drinks due to the possible development of bleeding from the digestive tract.
Acid intake by people with intensely metastatic cancerous tumors can provoke a worsening of the course of the disease.
During the period of using the medication, it is necessary to exclude the management of vehicles.
Pregnancy and lactation
Instructions for use "Antigrippin-Anvi" reports that when carrying the fetus it is forbidden to prescribe this remedy. If you need to use the drug while breastfeeding, lactation should be discontinued.
Cost and similar
You can buy the drug in the pharmacy at a very reasonable price (about 150-200 rubles).
In the event that the Antigrippin-Anvi medicine is contraindicated for the patient, it is replaced with such agents as Antigrippin-Maximum, Antigrippin, Teraflex, AntiFlu Kids, Rinza and others.
Consumer Reviews
Instructions for use "Antigrippin-Anvi" is required to read. In it you can find out when and in what dose the drug should be used to obtain the best therapeutic result.
According to consumer reviews, this medicine quite effectively eliminates the symptoms of colds and flu, and also quickly lowers body temperature. To prevent adverse reactions, take this medication in dosages strictly recommended by your doctor for no more than 3-5 days in a row.
The main disadvantage of the drug "Antigrippin-Anvi" is the presence of a large number of contraindications.