Clavulanic acid is an antibacterial bactericidal agent belonging to the group of semisynthetic penicillins. The drug gives the greatest effect in combination with the drug "Amoxicillin" - a broad-spectrum antibiotic. This combination has an irreversible inhibitory effect on the activity of beta-lactamases and is used to treat infections of the ENT organs and respiratory tract, skin, urogenital system, joints and bones.
There are drugs in which amoxicillin, clavulanic acid is already present . They are in the form of tablets, powders for the manufacture of an oral suspension or drops for oral administration, in the form of a syrup, as well as injectable solutions.
The drug "Amoxicillin" and clavulanic acid: action and properties
The acid itself is a weak antibacterial agent, however, it protects amoxicillin from enzymatic destruction, which allows the antibacterial effect to be fully exerted. The effect of the drug extends to a large number of gram-positive and gram-negative, anaerobic and aerobic pathogens, including their strains, which are resistant to antibiotics.
The drug "Amoxicillin" and clavulanic acid: indications
The medication is effective for the treatment of infections of the respiratory tract, throat, ear, nose, which include sinusitis, tonsillitis, otitis media, chronic and acute bronchitis, pneumonia, epidemic, bronchopneumonia, lung abscesses.
In addition, the tool is used for infectious diseases of soft tissues and skin (abscesses, boils, cellulitis, infected wounds, panniculitis, phlegmon). Clavulanic acid is used to treat diseases of the genitourinary tract and urogenital tract (including venereal), such as cystitis, pyelonephritis, urethritis, soft chancre, gonorrhea, salpingitis, endometritis, pelvioperitonitis, bacterial vaginitis, salpingo-oophoritis, postpartum sepsis, septic, abscess.
Also, the medicine is used if there are infections of the joints and bones in the body. Intravenous administration is prescribed for the prevention of infections associated with surgery.
The drug "Amoxicillin" and clavulanic acid: contraindications
Do not use the medication with hypersensitivity to penicillins and other antibiotics (beta-lactam), in order to exclude the possibility of anaphylactic shock. Contraindicated in patients with lymphocytic leukemia and infectious mononucleosis.
With caution, appointments are made for patients suffering from hay fever, allergic diathesis, urticaria, bronchial asthma. It is advisable to avoid the use of the drug, like other medicines, during pregnancy, despite the absence of adverse manifestations. When treating nursing mothers, traces of the drug were found in breast milk.
The drug "Amoxicillin" and clavulanic acid: price
Due to the large number of forms, dosages and varieties of the drug, the cost can vary significantly.