The drug "Pantoprazole" is characterized as an antiulcer. It reaches its maximum concentration after two to two and a half hours after taking twenty milligrams once. The medicine does not affect the motility of the digestive system. After the end of the therapeutic course, secretory activity returns to its original state after three to four days. When it enters the body, absorption occurs quickly enough. The bioavailability of the drug is about 77%. Metabolism occurs in the cells of the liver, decomposition products are excreted mainly through the kidneys.
Appointment
The tool "Pantoprazole" instructions for use recommends for lesions of the gastrointestinal tract (duodenum or stomach) of an erosive ulcerative type, due to the use of NSAIDs. Indications include manifestations of gatroesophageal reflux. The medication "Pantoprazole" (instructions for use indicates this) is prescribed as part of complex therapy for the eradication of Helicobacter pylori, other pathological conditions caused by increased secretion of the stomach.
Dosage regimen
The medicine is prescribed orally. In the treatment and for the prevention of ulcerative lesions, the recommended initial dose of Pantoprazole is 40 mg. The amount of medication can be increased to 80 milligrams. The duration of the therapeutic course is from two to eight weeks. Acceptance of funds is allowed when symptoms occur, "on demand." With prolonged use of NSAIDs, 20 mg is prescribed for the prevention of erosive lesions in the digestive system. In conditions caused by increased secretion, the recommended dosage is 80 mg. This amount is divided into two doses. In some cases, a dosage increase of up to 160 mg is allowed. The duration of treatment is set personally. For disorders of hepatic activity, the dosage is not more than forty milligrams.
The medication Pantoprazole. Instructions for use. Side effects
Based on therapy, the development of myalgia, anaphylactic reactions, allergies, diarrhea, liver failure, urticaria is likely. Patients may experience interstitial nephritis, headache, arthralgia, peripheral edema, photosensitivity. On the background of taking dry mouth, constipation, nausea before vomiting, thrombocytopenia, increased activity of liver enzymes. With the development of severe complications or the occurrence of undesirable consequences not described in the annotation, you should contact a specialist, stopping the use of the drug.
Contraindications
The medicine "Pantoprazole" (instructions for use warns about this) is not recommended for hypersensitivity, under the age of eighteen years, with dyspeptic manifestations associated with a neurotic condition. Prescribing the drug to pregnant or lactating is carried out exclusively for health reasons, after assessing the likely risk and expected benefits of therapy. Caution is exercised in treating patients with a moderate degree of liver failure. The presence of sorbitol in the medication should be considered. In this regard, the drug is not recommended for hereditary fructose intolerance.