"Blemaren" is a pharmacological agent, the action of which is aimed at alkalizing urine. The manufacturer produces the drug in the form of effervescent tablets, granules intended for dissolution in water. It can be used as a prophylactic, as well as with the aim of dissolving calcium oxalate accumulations, uric acid-oxalate and uric acid stones. It is often prescribed to patients who use cytostatics for the symptomatic treatment of porphyria of the skin, in order to further alkalize the urine. Reviews about "Blemaren" are available in large numbers.
Pharmacological forms
The manufacturer "Blemaren" is available in two pharmacological forms - in the form of granules and effervescent tablets, which are intended for the preparation of an oral medicinal solution.
We find out what is in the "Blemaren".
Composition, description
Blemaren effervescent tablets have a round shape and white color, flat. There is a smell of lemon. The active components of the tablet are: sodium citrate, potassium bicarbonate, citric acid. Additional components are adipic acid, macrogol 6000, lemon flavoring, sodium saccharinate, mannitol, lactose monohydrate.
20 tablets are packed in tubes made of plastic. Each tube is placed in a cardboard package, which is also equipped with a control calendar and indicator paper.
The active and auxiliary components of the granules are similar to those in effervescent tablets. Granules are packed in a package of 300 grams, in each package there is a measuring spoon, indicator paper and a calendar for control.
The price of Blemaren is of interest to many.
Pharmacological group
According to its pharmacological group, the medication refers to agents intended for the prevention of the formation and dissolution of calculi. Used as an element of the complex treatment of urolithiasis.
Indications for use "Blemaren"
The pharmacological agent recommends that specialists take it in the following cases:
- Prevention of the formation and dissolution of existing oxalate-calcium and uric acid stones.
- Symptomatic treatment of cutaneous porphyria.
- To alkalize urine in patients receiving cytotoxic or other medications that can enhance uric acid excretion in patients.
- Dissolution of mixed oxalate-uric stones when the concentration of oxalates does not exceed 25%.
Adult patients “Blemaren” is prescribed only if the indicated indications are available. The use of the drug as part of self-medication is unacceptable, since negative health effects can occur.
Patients under the age of 12 years, "Blemaren" is not assigned. For children from 12 years old, only a doctor should prescribe the drug, if there are strict indications.
"Blemaren" is not recommended for use in the lactation period and pregnant women. A similar limitation is connected with the fact that clinical practice does not have enough data on the effect of the drug and its harmlessness in these periods of a woman's life.
Contraindications
The drug has a number of absolute contraindications, in the presence of which the use of the drug is strictly prohibited. Among them:
- Circulatory failure.
- An insufficiency of hepatic activity, which has an acute course and a chronic nature.
- Chronic damage to the urinary tract with infections and pathogens that can break down urea.
Contraindications "Blemaren" should be strictly observed.
Drug use
The optimal dosage and dosage regimen for the drug is determined by a specialist taking into account the individual characteristics of the patient’s body and the current clinical condition of the pathology.
When using effervescent tablets, it is recommended that adult patients take up to 6 pieces per day. Reception should be carried out after a meal, while the tablet should be previously dissolved in a liquid. For this, both plain water and tea, juice, mineral water are suitable. The daily dose must be divided into several doses.
If the dosage is calculated by a specialist correctly, then the urine should have the following acidity level:
- 6.2-7 - if dissolution of uric acid deposits is required.
- 7.5-8.5 - if necessary, dissolve the cystine stones.
- 7.2-7.5 - in the treatment of porphyric manifestations.
- Minimum 7.0 - when using cytostatics.
It is for pH control that each box of the drug is equipped with indicator strips and a special calendar, which will allow the patient to monitor the course of therapy.
If the acidity of the urine has a lower level, it is necessary to coordinate an increase in the dosage with a specialist, and, conversely, if the acidity exceeds the specified values, the dose should be reduced. Most often, Blemaren therapy takes up to 6 months.
PH control must be performed three times a day immediately before using the drug. The color obtained on the indicator should be compared with the attached scale and enter the value in the calendar.
Patients under 12 years of age are forbidden to take the drug. After this age, the drug can be prescribed, but only if there are strict indications, and therapy should be carried out under the supervision of a doctor.
Negative impact
According to reviews of Blemaren, against the background of its use, various negative reactions can develop, among which:
- Allergic manifestations.
- Metabolic alkalosis.
- Dyspeptic disorders.
- Swelling that develops as a result of sodium retention.
If these side effects of Blemaren occur, they should be reported to the doctor. Probably, a dose adjustment, a change in the treatment regimen or, at all, drug withdrawal will be required.
How to take "Blemaren" in conjunction with other means?
Interaction with other medicines
When used together with citrate or aluminum based preparations, aluminum absorption may develop. To prevent a similar effect will allow the observance of a two-hour interval between doses of drugs.
The composition of the drug contains potassium, which can reduce the effectiveness of cardiac glycosides.
Some antihypertensive drugs, such as NSAIDs, analgesics, potassium-sparing diuretics, ACE inhibitors and aldosterone antagonists, can inhibit the excretion of potassium. The advisability of combining these drugs during therapy should be determined by the doctor.
Special instructions for use
When conducting therapy using Blemaren, it must be borne in mind that the average dose contains 0.9 grams of sodium and 1.5 mg of potassium. Such a quantity of these substances can cause negative effects in those cases when the patient adheres to a diet without salt.
The use of a medication in patients with chronic renal failure is allowed only if they have no delay in potassium ions. "Blemaren" can be used in the treatment of patients with diabetes.
During therapy, patients are advised to adhere to a certain diet and reduce the intake of protein-rich foods, as well as those that are saturated with purine formations. It is important to drink more than one and a half liters of water per day.
The drug does not affect psychomotor reactions and concentration of attention, and therefore the patient using it can perform work related to driving a car or complex mechanisms.
There are currently no recorded data on overdose cases.
Analogs of Blemaren
If necessary, "Blemaren" can be replaced with medications, the therapeutic effect of which is similar, however, such a replacement must be agreed with the doctor. It is important to remember that all analogues have a number of their own contraindications and are able to provoke various negative effects. Therefore, the feasibility of replacing the drug should always be determined by the doctor.
The most popular analogues of "Blemaren" are:
- "Urolesan." It is a combined drug based on plant components. The medication has an antispasmodic, diuretic and choleretic effect. The manufacturer produces in the form of drops, syrup, capsules (having a green gelatin shell). Inside the capsules is a yellowish powder with inclusions and spruce aroma. Each package holds 40 capsules. The drug in syrup form is packaged in containers of 90, 180 ml. Externally, the syrup looks like a liquid of greenish or yellowish color, has a specific smell. Drops are packed in 25 ml bottles, have a green-brown color.
- "Fitolizin". It has anti-inflammatory, diuretic, antispasmodic effect. It allows you to remove stones and prevent their formation. Produced by the manufacturer in the form of a paste having a brownish-green color and a specific herbal smell, it is packaged in 100 grams in tubes. The paste is intended for the manufacture of a suspension, which is then taken orally.
- "Uronefron." The manufacturer produces the drug in the form of drops (intended for oral use), gel and syrup. It is a herbal preparation with a combined effect (anti-inflammatory, diuretic, antimicrobial, antispasmodic). The use of the drug helps prevent the formation of calculi, helps to remove them together with urine.
Cost
In Russian pharmacies, the average price of "Blemaren" is 1160 rubles. However, it may vary depending on the pricing policy of the pharmacy and the region of distribution.
We will review the reviews of Blemaren further.
Reviews
This drug is widely used in clinical practice. Patients who used the drug report its effectiveness in the fight against kidney stones, however, they note that the desired effect can only be achieved by strictly following the doctor's recommendations and using the drug for a long course.
Significant relief from the use of the medicine also occurs with gout, and the important advantage of Blemaren, according to reviews, is rarely arising negative effects.
The negative characteristics of the drug are most often associated with its relatively high cost.
You must remember that you should not self-medicate - the appointment of "Blemaren" should be carried out by a doctor.