In the article, we consider the composition of the drug "Omez" and instructions for it. Fast food and soda, food on the go and bad habits provoke the development of diseases of the gastrointestinal tract such as gastritis, erosion or ulcers of the stomach or duodenum. These are quite common health problems in modern people. In order to cure these pathologies or prevent relapses, doctors prescribe medications that have a protective effect on the mucous membranes of organs. One such drug is Omez. We will describe this tool in more detail, find out how well it helps. At the end of the article will also be given reviews and analogues. The composition of the drug "Omez" for many raises questions.
Mechanism of action
"Omez" is a drug from the group of drugs that have a pronounced antiulcer effect. Against the background of taking the medication, the production of hydrochloric acid decreases and Helicobacter pylori is destroyed (the main reason for the development of stomach ulcers).
After the first use, the absorption of the active substance “Omez” takes place only by 30–40%, however, if regular use is ensured, the digestibility will double. The effect of the drug is quite quick, the maximum concentration in the blood is observed already 30-60 minutes after use. The effect persists for a whole day. The secretory activity of the stomach is completely restored on the third or fifth day.
A kind of medication “Omez D” also has an antiemetic effect. Due to which the patient ceases to suffer from nausea. This is due to the fact that peristaltic contractions of the antrum of the stomach increase and the tone of the esophagus sphincter increases. Until the end, the mechanism of action of this drug was not determined. It can be assumed that they have an effect on the area in the brain that is responsible for the activity of the digestive organs.
The composition of the drug "Omez" and form release
The drug is produced in:
- capsules;
- lyophilisate for infusion;
- powder for the manufacture of a suspension.
Omeza, Omeza D and Omeza Insta have different formulations or dosage forms. So, Omez and Omez Insta have only one active component in their composition. It is in this case about omeprazole. And in the composition of "Omez" in capsules, "Omese D", the substance domperidone is additionally contained. The release form of Omeza Insta is powder. Another difference is that in the list of its auxiliary components there is baking soda, which instantly neutralizes hydrochloric acid. Omeprazole will begin its work a little later.
The composition of "Omeza", "Omeza D" and "Omeza Insta" for each dosage form
So, first, consider the composition of the drug "Omez Insta" in powder. Its active component is omeprazole. Excipients in the form of sodium bicarbonate; sucrose; xylitol sucralose; xanthan gum; mint flavoring.
The composition of "Omez D" in capsules: the active components of domperidone, omeprazole. MCC (microcrystalline cellulose) are present as auxiliary; magnesium stearate; sodium carboxymethyl starch; colloidal silicon dioxide; sodium lauryl sulfate; talc.
"Omez" in capsules consists of omeprazole, as well as mannitol; lactose free; sodium lauryl sulfate; sodium hydrogen phosphate; sucrose; hypromellose.
Omez in the form of a lyophilisate contains omeprazole. And auxiliary components in the form of disodium edetate; sodium hydroxide.
Not on sale "Omez" in tablets. The composition of the drug in capsules, powder and lyophilisate is described in detail in the instructions.
In what cases is the drug indicated?
The preparations “Omez” and “Omez Insta” are prescribed for:
- gastroesophageal reflux disease (with its various forms);
- peptic ulcer of the stomach and duodenum (well treats acute ulceration and prevents relapse);
- prolonged use of NSAIDs (non-steroidal anti-inflammatory drugs); the product protects the gastric mucosa from damage, eliminates the symptoms of dyspepsia caused by anti-inflammatory therapy;
- diseases in which there is a stimulation of the secretory activity of the stomach (peptic ulcer, Zollinger-Ellison syndrome, mastocytosis);
- for eradication (complete eradication) Helicobacter pylori in the treatment of ulcerative pathologies of the stomach and intestines.
What is the purpose of the Omez preparation? In children, the drug effectively treats gastroesophageal reflux and peptic ulcer of the stomach and / or duodenum.
"Omez D" is prescribed in the case of the same indications when the use of funds based on one omeprazole did not give the desired effect.
So, we examined the indications for the use of the Omez drug, and then we will talk about contraindications.
Does the medication have contraindications?
Contraindications to the use of "Omeza" and "Omeza Insta" are:
- hypersensitivity to the components of the drug;
- sucrose / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption;
- simultaneous administration of drugs based on erlotinib, posaconazole, nelfinavir and atazanavir;
- age up to two years (it is possible to use in children from 2 years old strictly as prescribed by the doctor);
- body weight less than 20 kg.
"Omez D" is prohibited for patients with:
- internal bleeding;
- bowel obstruction;
- perforation (perforation) of the digestive tract;
- prolactinoma;
- children under 12 years old;
- lactation.
In pregnant women, the use of any form of medication is possible only with strict indications. And “Omez” and “Omez Insta” are allowed to be taken by nursing mothers, since omeprazole does not negatively affect infants. But, in accordance with the instructions for use, Omez D is not allowed to be used when breastfeeding.
Why is this so? The fact is that the main difference between “Omeza D” and the usual “Omeza” is that, according to the instructions, another active component is included in the composition of “Omeza D” - domperidone. This substance stimulates the synthesis of prolactin - the hormone responsible for lactation. Drugs based on it are prescribed for insufficient milk production. This explains lactation in the list of contraindications, that is, the manufacturer is thus insured against possible consequences. True, despite this, Omez D is sometimes prescribed for breastfeeding.
Drug interaction
How does omeprazole as part of the Omez preparation interact with other drugs? Let's figure it out:
- Against the background of this active component, iron is poorly absorbed (and, accordingly, drugs such as Maltofer, Sorbifer, Durules), some antifungal agents (Introconazole and Ketoconazole), as well as antibiotics from the group of ampicillins (such as Sultasin) , "Ampicillin").
- While taking omeprazole as part of Omez in capsules or powder, the strength and duration of exposure to drugs such as Diazepam, Phenytoin, and indirect anticoagulants (these are Dikumarin, Warfarin) are enhanced.
- The effect of drugs that are depressing on the hematopoietic system is amplified (Cordox, Amikar can be attributed here).
It is forbidden to take “Omeza D” and the following groups of medicines at the same time:
- antacids (drugs that lower the acidity of gastric juice - Almagel, Rennie) - the effectiveness of the Omez D therapy decreases;
- anticholinergics (drugs that block cholinergic receptors - Diphenhydramine, Cyclodolum) - the effect of Omeza D is neutralized;
- macrolides (Erythromycin, Azithromycin), Nefazodon and HIV protease inhibitors (Ritonavira, Indinavira) - the content of domperidone in the blood rises.
If prolonged use of the drug is carried out, especially against the background of the simultaneous administration of diuretics (Furosemide, Diuvere), hypomagnesemia may develop. In this case, the doctor may additionally be prescribed magnesium-containing agents.
Side effects
Also, with prolonged use, the development of adverse reactions of the body such as:
- Violations of the stool in the form of constipation, in which defecation may be absent for several days. In rare cases, a reverse reaction is observed in the form of prolonged diarrhea.
- Discomfort in the abdomen - this can be an unpleasant sensation, and sometimes pain in the abdominal region. Usually, symptoms worsen immediately after taking another capsule or dose of suspension. Also, patients often complain of increased gas formation or, simply, flatulence.
- Stomatitis. An ailment develops due to the antibacterial effect of the drug.
- Impaired liver function. There is a decreased activity of liver enzymes. Due to the load on this organ, various pathologies can develop, including hepatitis.
- Nervous Disorders. Against the background of long-term use, the work of the nervous system is disrupted. The patient's mood changes dramatically, depressive states, apathy occur. In some cases, nervous irritability, irritability are noted.
- Allergic reactions. The nature and intensity of the reactions are influenced by the individual characteristics of the patient. Patients complain mainly of skin rashes, severe itching, urticaria. Anaphylactic reactions in severe cases, accompanied by respiratory spasms, are not ruled out.
- Increased sweating. Against the background of taking "Omez", a malfunction of the kidneys is observed, due to which the fluid is retained in the body, and the activity of the sweat glands is activated.
- General malaise in the form of loss of strength, drowsiness, headaches, lack of appetite. A frequent side effect is nausea and vomiting, especially in the morning.
How to drink Omez?
Instructions for use
All types of medication are consumed regardless of food intake. The dosage form affects the method of use:
- capsules are swallowed whole, washed down with water;
- the powder is diluted with a small amount of water and immediately taken orally;
- a solution is prepared from the lyophilisate and injected into a vein, and this should be done by a medical professional.
The powder from the bag dissolves with plain water, it is better not to use other liquids.
Pharmacy leave terms and price
The drug is released to the patient on prescription.
The average cost of the drug may also vary, depending on the form of release:
- The drug "Omez" in a lyophilizate 40 mg costs 150 rubles.
- In capsules, 10 mg costs 75 rubles.
- In capsules, 20 mg can be purchased for 150 rubles.
- In capsules, 40 mg costs 270 rubles.
- In capsules 10 mg + 10 mg - 300 rubles.
- Omez Insta 20 mg - 80 rubles.
Analogues of the drug
There are drugs with a similar composition on sale. Their effect and indications for use are similar.
So this is:
- Omeprazole;
- "Losek MAPS";
- "Orthanol";
- Ultop.
In analogues, the active substance is omeprazole. Contraindications, side effects of these drugs also coincide.
It is important to understand that only the attending physician should select a replacement. Self-medication is unacceptable.
Reviews
Reviews about the drug "Omez" are available in large numbers. It is considered a fairly effective remedy for heartburn, gastritis, and gastric ulcer. The speed of its action is well known, the result is noticeable after a few minutes.
Doctors prescribe a medication for increased secretion of gastric juice.
According to reviews, against the background of the reception, pain in the stomach disappears, heartburn disappears, literally on the second day.
We reviewed the composition and instructions for the use of "Omez". It is a drug that is highly effective in the treatment of ulcerative pathologies of the digestive tract and other ailments, which are accompanied by increased production of gastric juice, nausea, and also vomiting. It helps quite quickly and for a long time. Side effects, if they occur, are quite rare.