Have a glass of wine on Friday or a martini at the club with friends on Saturday? The usual thing. But even at such minimal doses, alcohol may not be compatible with the medications you are taking.
Anaprilin - what is it?
"Anaprilin" (propranolol hydrochloride) - a blocker of β-adrenergic receptors, a drug for the cardiovascular system, which has a hypotensive, antiarrhythmic, antianginal effect. It inhibits lipolysis of adipose tissue, preventing an increase in the level of fatty acids in the blood. The bioavailability of propranolol is 26%.
It is prescribed for cardiomyopathy, atrial and sinus tachycardia, ischemic heart disease, high blood pressure, angina pectoris, etc. Anaprilin improves peripheral vascular resistance and normalizes blood pressure.
Contraindications
"Anaprilin" is contraindicated in patients with bronchial asthma, with heart failure. The drug is not prescribed for pregnant and lactating women. He has a list of side effects: cramps, nausea, vomiting, ischemic colitis, heart failure, dizziness, insomnia or drowsiness, depression, hallucinations, circulatory disorders, diarrhea or constipation, cough, shortness of breath, exacerbation of chronic psoriasis, decreased libido and potency, etc. . d.
Interaction with other medicines
If any other medicine is taken with Anaprilin, you should definitely inform your doctor. The antihypertensive effect of Anaprilin can increase with the simultaneous use of sympatholytics, hypotensive, hydralazine, anesthetics, etc. The antihypertensive effect of Anaprilin can decrease with the simultaneous administration of nonsteroidal anti-inflammatory drugs, estrogens, glucocorticoids (steroid hormones). Thus, you should not take Anaprilin before or after visiting the dentist if you plan to take non-steroidal anti-inflammatory painkillers, for example, nimesulide.
"Anaprilin" is able to slow down the excretion of lidocaine and aminophylline, increasing their concentration in blood plasma, prolongs the action of non-depolarizing muscle relaxants. The joint administration of radiopaque substances increases the risk of anaphylactic shock, so before an MRI, CT scan using contrast, Anaprilin is better not to take. In general, before agreeing to use radiopaque substances, it is better to inform your doctor about the medicines you have taken over the past 12-24 hours.
The simultaneous use of Anaprilin and allergens for immunotherapy or skin tests dramatically increases the risk of a severe systemic allergic reaction.
Anaprilin can mask the manifestation of tachycardia in patients with diabetes who are taking insulin or any drugs that lower their glucose levels.
If an operation with anesthesia is prescribed, you should stop taking Anaprilin a few days before it or inform your doctor and ask him to choose anesthesia with the least inotropic effect.
Interaction with Alcoholic Beverages
Can Anaprilin be used with alcohol? To immediately put all the dots on the "i", the answer is no. Anaprilin and alcohol are incompatible.
Despite all the advantages, the drug has an extensive number of contraindications and special reception conditions. The instructions indicate that for the entire period of taking "Anaprilin" it is not recommended to take ethanol and alcohol-containing drinks.
The simultaneous use of Anaprilin and alcohol can lead to a critical decrease in blood pressure, which, in turn, will cause orthostatic collapse and death.
Orthostatic collapse is accompanied by inadequate supply of blood, and hence oxygen, to the brain as a result of an excessive decrease in pressure.
Anaprilin should not be mixed with substances that affect the functioning of the cardiovascular system, including alcohol-containing drinks, as well as tranquilizers and antipsychotics.
Alcohol, getting into the blood plasma, promotes the connection of red blood cells, which in certain cases leads to the formation of blood clots.
Blood saturated with alcohol toxins reaches the heart. These toxins destroy the body forming scars, as a result of which the heart muscle ceases to be elastic and works for wear. The heart does not have time to pump blood and "chokes" it. Hence the rhythm disturbance and other diseases.
With prolonged use, Anaprilin exhibits hepatotoxicity. This is a property of almost all drugs, so only a doctor should choose a combination of medicines. The liver is therefore destroyed by alcohol, so it should not be finished off with Anaprilin along with alcohol-containing drinks.
What does Anaprilin do with alcohol?
Anaprilin enhances the effects of alcohol on the body. Therefore, even if a person drinks only a little, he may show all signs of heavy alcohol intoxication:
- dizziness;
- confusion of consciousness;
- lack of coordination;
- memory loss.
Therefore, Anaprilin and alcohol, with which there is no compatibility, cannot be taken. Alcohol enhances the absorption of the drug, which can lead to an overdose. The latter is dangerous in that pressure can drop too sharply. Hypotension can be so significant that urgent hospitalization is not excluded.
Alcohol after Anaprilin
Even if you have not been prescribed Anaprilin as a course, but you drank one tablet, you need to refrain from drinking alcohol for 5 hours after taking it. This time will be enough for the active substance to be absorbed into the blood. The half-life of "Anaprilin" after a single dose is usually 3-5 hours. When taking "Anaprilin" course, this time increases to 12 hours. Therefore, if you take "Anaprilin" course, you should refrain from alcohol for at least 12 hours after taking the pill.
This does not apply to people with diseased kidneys and liver. Up to 90% of propranolol is excreted by the kidneys. The liver is actively involved in the neutralization of alcohol poisons. With the malfunctioning of these organs, the excretion of substances slows down. If you have a disease of these organs, it is best not to drink alcohol within 24 hours after drinking.
If Anaprilin was taken with alcohol, the following symptoms can be observed:
- nausea;
- vomiting
- rapid breathing;
- spasms of blood vessels;
- a large decrease in pressure;
- loss of consciousness;
- collapse;
- sometimes death occurs.
Anaprilin and alcohol greatly enhance each other's action. A small amount taken can be a lethal dose.
After alcohol
Ethyl alcohol in the body breaks down into small particles, and one of these particles is acetaldehyde. This is a strong poison that severely damages internal organs. With the accumulation of acetaldehyde in the body, poisoning occurs. That is why a person does not feel well, his hands tremble, his heartbeat quickens.
"Anaprilin" after alcohol can be taken. Moreover, it is recommended by doctors for severe hangover. To eliminate the symptoms of poisoning and to stabilize blood circulation, you can drink Anaprilin. But it is up to you to decide whether Anaprilin can be in this case, only the doctor. A simple layman does not understand what kind of reaction substances enter in his body, and he cannot judge the consequences. If the body has not yet removed the remnants of ethyl alcohol, then perhaps the doctor will forbid taking Anaprilin.
Possible consequences
The combined use of Anaprilin with alcohol can cause toxic damage to the heart muscle, and blocking the transmission of the signal from the atrium to the ventricle in general can lead to cardiac arrest. Ethyl alcohol strongly inhibits the activity of the nervous system and heart. The simultaneous use of Anaprilin and alcohol, or failure to observe sufficient time between doses, can lead to:
- hypoglycemia, because the composition enhances the drop in blood sugar;
- drop in blood pressure;
- peripheral vasospasm with the appearance of cold in the limbs;
- nausea
- weakness and even fainting.
Anaprilin and alcohol. Reviews
If we analyze consumer reviews, the picture is very mixed. Some patients taking Anaprilin indicate that co-administration with alcohol leads to a normalization of blood pressure and well-being. However, another part of patients responds to this combination extremely negatively and talk about a deterioration in their general health, about cardiac abnormalities, and about the development of a depressed, depressive state. The reviews of some patients or their relatives indicate that the combined use of Anaprilin and alcohol often ends in death.