The hormonal background has a tremendous effect on the body of every woman. That is why the presence of all kinds of failures in the endocrine system entails the development of pathological conditions. Various deviations from the norm can occur at different stages of a woman’s life, for example, at the very beginning of menstruation, during the period of gestation or after the onset of menopause. Progestogens are one of the most significant hormones necessary for the process of conception and the normal course of pregnancy.
Features
Gestagenic medicines are often used as oral contraception, as well as in the treatment of many gynecological defects provoked by hormonal disruptions. But it is very important to understand that just knowing the name of the drug with gestagen is not enough. A specific medicine and a specific dosage can be prescribed only by a specialist and only after an appropriate examination. But whether women should be wary of the names of drugs with gestagens in the prescribed recipes, you will learn from this article.
Why are medicines needed?
Drugs in the progestogen category are hormonal medicines made on the basis of natural progesterone and its artificial derivatives, as well as analogues, for example, pregnin, allylestrenol, hydroxyprogesterone capronate, norethisterone. The use of such funds is caused by a deficiency of natural hormones.
Progesterone is not in vain considered the second most important hormone in the female body. And not surprising, because it depends on him the ability not only to conceive, but also to endure a healthy baby, as well as the general condition of the endometrium and uterus. Progesterone deficiency is often the cause of female infertility. This hormone is produced by the adrenal glands, as well as by the corpus luteum, which appears after the egg leaves the membrane. That is why its highest concentration in the blood is noted immediately after ovulation.
Progesterone function
Progestogens belong to the group of steroids. Their main share is produced by the ovaries and corpus luteum, partly by the adrenal glands.
A key function of these hormones in the body of women is the monthly preparation for conception. Gestagens provide several tasks:
- creating favorable conditions in the female body, which are necessary for the process of conception and the normal course of pregnancy in the future;
- preparation for childbirth and for motherhood proper - active strengthening of the muscles of the birth canal, normalization of metabolic processes, preparation for breastfeeding;
- cellular effect on the endometrium, providing protection against the occurrence of all kinds of tumors and hyperplasia;
- maintaining favorable conditions for the beginning of embryo development;
- exposure to the uterine mucosa to form a protective mucous plug;
- stimulation and control of the full development of the breast during the formation of the body, as well as secondary sexual characteristics - in adolescence.
Classification
The names of drugs with progestogens can be found in several categories of medicines containing progesterone or its artificial analogues. They can be divided into two large groups: oral contraceptives and hormone replacement treatment. There are also several forms of release.
- Tablets. Modern drugs with microdoses of gestagens are highly effective and have a minimal amount of side effects, unlike estrogen drugs. In the reviews presented on the network, you can find many names of drugs with gestagens that have excellent qualities. According to women, such pills are convenient to drink, however, it is necessary to strictly adhere to a certain schedule.
- Injections. Depending on the name of the drug with gestagens for women, the duration of one injection is determined. The drug is injected intramuscularly into the buttock. On average, the duration of the effect reaches about three months.
- Implant. Such a drug is a specific sterile capsule that throws gestagens into the bloodstream for three years, thus maintaining their normal concentration in the body. Over time, the implant does not resolve, so it should be removed later.
- Intrauterine device Standard contraceptive with high effectiveness.
- Ointments. They have a local effect, are famous for their low concentration and high safety. It is thanks to these properties that they are often prescribed to women with a certain history of pathologies.
Before starting treatment, a consultation with an endocrinologist or gynecologist is required. Only a doctor can determine the necessary name of a drug with gestagens for a woman, taking into account the general state of health and the nature of the revealed pathology.
Indications for the use of hormone therapy
Progestogens - means, the use of which may be required at any age. Hormonal abnormalities in women under the age of 45 are the result of an unhealthy diet, a variety of diseases, and an improper lifestyle. So, many ladies face similar problems because of too rigid diets, chronic inflammation of the appendages and other organs of the reproductive system, too much physical exertion, as well as incorrect activity of the pituitary or thyroid gland.
After 45 years, women have another difficult period - menopause. It is against the background of this condition that hormonal changes occur in the body, due to which the concentration of progesterone and estrogen is significantly reduced. In such cases, it is recommended to take drugs with gestagens. A list with the names of the drugs and their main purposes can be found below.
When is treatment needed?
For hormone therapy, there are several main indications.
- Too long the menstrual cycle, its irregularity. Natural progesterone prepares the uterine endometrium for egg implantation. If conception did not take place, menstruation begins - the inner layer of the uterine cavity is rejected. If the concentration of the hormone is lowered, natural secretions simply do not begin.
- Intensive premenstrual syndrome. It is characterized by sudden mood swings, as well as severe pain in the abdomen and chest.
- Infertility. When a woman’s body does not experience the natural processes required for implantation and conception.
- Fibrocystic mastopathy. An increased concentration of the hormone, which in a woman carrying a child’s child prepares dairy women for the period of feeding, in non-pregnant women provokes the formation of pathological neoplasms.
- Myoma. Drugs with gestagen are necessary to lower the level of estrogen, which in excessive quantities adversely affects the uterus.
- On the eve of the planned IVF. In this case, these funds are used to delay menstruation. Drugs with progestogens are used to suppress concomitant natural processes that may interfere with successful fertilization and embryo transfer. Although such therapy is not needed in all cases.
Names of drugs with progestogens for women
The names of funds of different groups are determined solely by the pharmaceutical company by which they were produced. Progestogens can be synthetic and natural. Artificial means are divided into several categories:
- Hybrid
- derivatives of 17-hydroxyprogesterone;
- derivatives of 19-nortestosterone.
A representative of the natural group is considered progesterone. The most popular names for drugs with progestogens are Progesterone and Utrozhestan. Artificial derivatives of 19-nortestosterone are represented by Ovestin, Trisequens and Postinor medicines. Synthetic derivatives of 17-hydroxyprogesterone are included in Divisek and Dufaston. And the category of hybrid products include Yarina and Zhanin.
List of the best names of drugs with progestogens
- "Utrozhestan". It is produced in the form of capsules for oral use. It is often prescribed to women with infertility, mastopathy, pronounced PMS, abnormalities in the menstrual cycle, as well as menopause in combination with estrogens.
- "Progesterone". It is produced in the form of an oily medicine. It is indicated for use with an irregular menstrual cycle, menopause, endometriosis, hirsutism, infertility, breast and uterine tumors, pregnancy after IVF.
- "Trisequens". Another popular name for the drug is with progestogens. What is this tool used for? "Trisequens" are pills that are used for estrogen deficiency or to prevent fractures and osteoporosis in women during menopause.
- "Ovestin." Intravaginal cream used for infertility against the background of malformations of the cervix, atrophy of the mucous membrane of the genitourinary system due to estrogen deficiency, rehabilitation after surgery in the vagina.
- Postinor. Pills used for emergency contraception after unprotected sex.
- Dufaston. Tablets that are prescribed for progesterone deficiency due to pathology, or as replacement therapy.
- Divisek. The name of the drug with gestagens to delay menstruation before the planned IVF. Also taken with a diagnosed estrogen deficiency during menopause.
- "Yarina" and "Janine." Tablets and pills used for contraception.
Other types of drugs with progestogens
What other medicines with these hormones can be found in pharmacies? Here is the full list of names of drugs with gestagens:
- injections - "Amen", "Tsikrin", "Depot-checker", "Duralutin", "Amen";
- implants - "Implanon", "Norplant" and "Norplant-2";
- intrauterine devices - "Mirena";
- tablets - Pregnin, Norlutat Augestin, Vizanne, Primolut-Nor, Turinal, Nemestran, Dianor, Gestest, Orgametril, Norkolut, Fortilyut, " Anovule ";
- emergency contraception - Neogest, Postinor and Escapel;
- oral contraceptives - Mikroval, Nor-QD, Exlutena, Norgeston, Mikronor, Exluton, Femulen, Novidai, Metrodiol, Charozeta, Follistrel, Continuin, Model Mom, Lactinet.
Contraindications
Even in their pure form, progestogens have a much smaller number of restrictions than estrogens. They are allowed for use by women during breastfeeding, as well as those who suffer from diabetes and hypertension.
A positive property of drugs with progestogens is considered to be a relatively rapid restoration of fertility after stopping treatment.
The main contraindications for the use of such medicines are the following conditions:
- cervical dysplasia;
- liver defects - pathological neoplasms and cirrhosis;
- thrombophlebitis;
- increased intracranial pressure;
- some abnormalities of the uterus.
In the end
Before proceeding with therapy, you should definitely visit a gynecologist and undergo an appropriate examination. Only a specialist can correctly choose the right drug with gestagens.