The medicine
"Tamoxifen" instructions for use relate to the group of
antitumor drugs with non-steroidal and antiestrogenic effects. The use of this tool stimulates the release of pituitary hormones, relieves the inflammatory process and effectively stops the development of tumors. Starting with the first dose, the drug blocks the action of estrogen for several weeks, without causing unwanted side effects associated with excessive tissue growth. In male patients suffering from impaired ejaculation, the use of Tamoxifen can provoke an increase in the concentration of testosterone in the plasma. If we consider the pharmacokinetics of this antitumor agent, then it begins to act actively only thirty minutes after administration, reaching the highest levels within five to seven hours.
Tamoxifen is produced in the form of yellow tablets containing ten, twenty, thirty or forty milligrams of tamoxifen citrate as the main component. Additional ingredients are: cellulose, sodium starch, magnesium stearate, povidone and lactose. The shell contains polyethylene glycol,
titanium dioxide and hypromellose. In addition, a small amount in the medicine contains lactose.
To prescribe Tamoxifen tablets, the instruction for use recommends to patients with cancer of the endometrium, prostate or ovary, breast and mammary glands. Also, this medicine is very effective for tumors in the kidneys or melanoma. With sarcoma, the drug Tamoxifen should be started in a similar manner. Instructions for use and notes the positive results from its use for the treatment of nodular formations of various etiologies.
It is strictly forbidden to take this antitumor agent in case of individual intolerance to tamoxifen citrate or any other components of the drug. Leukopenia, thrombophlebitis, pregnancy, the lactation period, cataract and severe forms of cardiovascular disease are also contraindications to the use of this drug "Tamoxifen"
- the instructions for use draw attention to this. In addition, it should not be taken in patients with hepatic or renal failure. With extreme caution, Tamoxifen tablets are prescribed for thrombocytosis, thrombocytopenia, brain diseases, or hypercalcemia.
Taking this medicine in some patient groups can cause dyspepsia, nausea, vomiting, cholestasis, decreased appetite, diarrhea, and liver infiltration. Confusion, thrombocytopenia, headache, leukopenia, drowsiness, fever and dizziness can also occur as a result of taking Tamoxifen tablets. Side effects include the risk of uterine bleeding, burning and itching in the genitals, cystic tumors, urticaria, dermatitis and bronchospasm. In addition, there may be a decrease in potency, vaginal discharge, skin rash, and hyperemia.