“Clindacin B Prolong” is a very effective anti-fungal treatment product intended for topical use. It has a pronounced antibacterial effect and is used for the treatment of various kinds of gynecological pathologies.
When is the drug used?
This vaginal cream must be used for therapeutic purposes in the presence of vaginosis caused by a fungal or mixed flora that is susceptible to clindamycin.
Composition specifics
According to the instructions for use, Clindacin B Prolong against the fungus contains two active ingredients that are clindamycin phosphate, as well as butoconazole nitrate. The mass fraction of these components in the composition of the drug is 2.376 mg and 2 g. Excipients are:
- cytostearyl alcohol;
- isopropyl myristate;
- propylene glycol;
- water;
- macrogol cytostearate;
- sodium hydroxide;
- hydroxypropyl diacramphosphate;
- preservative component Euxyl PE 9010.
Candles “Clindacin B Prolong” are also available. Instructions for use, enclosed in each package, explain in detail the rules for their use.
Therapeutic characteristics of the drug
Butoconazole is included in the list of imidazole derivatives, has a detrimental effect on microsporium fungi, candida, epidermophytum, some gram-positive microorganisms and ringworm. The active substances of the drug exhibit high bactericidal activity against yeast-like fungi. When tissues get inside, they inhibit the formation of ergosterol in cell membranes, contributing to the thinning of their walls. Also, lysis of fungal cells is noted. Instructions for use with “Klindatsin B Prolong” with 3 or 1 applicator in the kit (depending on the amount of treatment composition) are available in each pack.
The active substance is one of the antibacterial bacteriostatic substances that are part of the group of linkosamides. It has a very wide range of effects, it is characterized by activity against fusobacteria, gram-positive cocci, corynebacteria, streptococci, anaerobes, mycoplasmas, clostridia, gram-positive microaerophilic cocci, actinomycetes, propionic acid bacteria, bacteroids.
Some strains of clostridia are sensitive to clindomycin, but some of them are resistant to the antibiotic of the bacteriostatic type. For this reason, when an organism is infected with clostridia, antibioticograms are necessary to determine the sensitivity of pathogenic microflora to various drugs. This is confirmed by the instructions for use and radar (drug register) for Klindatsin B Prolong .
This drug differs from similar drugs in that it has a creamy hydrophilic base, as a result of which it turns into a gel when heated to body temperature. Due to the creamy structure, this drug is quickly injected deep into the vagina. With intravaginal use, the drug is transformed, and its active components are uniformly distributed on the vaginal walls, staying here for a long period - from one to three days, having a healing effect.
The characteristic form of the drug
According to the instructions for use, “Clindacin B Prolong” in the form of a cream outwardly looks like a whitish or grayish suspension with a pronounced specific aroma. This antifungal agent is available in bottles having a volume of six or twenty grams.
Instruction for use
As indicated by the instructions for use, "Clindacin B Prolong" is used intravaginally like antibacterial suppositories, however, the method of administration has its own characteristic features. For this purpose, the use of a vaginal applicator is required.
It must be inserted deep into the vagina in a horizontal position, slowly pressing the plunger, while there should not be any discomfort. It should also be noted that the vaginal applicator is completely filled with cream only when the piston rests on the stop. After the drug is introduced into the vagina, you need to carefully pull it out and dispose of it. The single dose recommended for use is five grams, which corresponds to the applicator filled to the end. This antifungal cream is administered once a day, and treatment should continue for three days. This is confirmed by the "Klindatsin B Prolong" instructions for use and reviews.
Features of use during pregnancy and breastfeeding
Only a doctor can decide on the use of this drug in this category of patients. It is also possible that the specialist will prescribe another drug with an identical effect in the form of suppositories, in the instructions for which its use during pregnancy or lactation will be allowed. This also confirms the instructions for use for Klindatsin B Prolong. We will complete the description of the drug by listing the contraindications for its use.
Contraindications
The use of ointment in cases is excluded:
- ulcerative colitis;
- when the patient's age is less than eighteen years;
- colitis of a pseudomembranous nature;
- high susceptibility to this drug;
- Crohn's disease.
Precautionary measures
Antifungal therapy is prescribed with caution if the patient is prone to various allergic manifestations. If irritation of the vaginal mucosa occurs during treatment, its use should be stopped immediately.
If there is no positive dynamics, you must consult a doctor and then conduct another microbiological examination. Thanks to laboratory analysis, you can determine who is the causative agent of gynecological pathology.
You can not use vaginal cream in parallel with other intravaginal drugs.
This points to the "Clindacin B Prolong" instructions for use. Analogs will be considered below.
Side effects
Suppositories with clindamycin in the composition and cream are fairly well tolerated, however, in some cases, a local reaction may occur:
- acute itching;
- pain and spasm in the lower abdomen;
- swelling of the mucous membranes;
- allergy;
- burning.
No cases of overdose were detected.
Analogs
The vaginal product “Clindacin B Prolong” (instructions for use is discussed in this material) has such an analogue as “Dalacin”, produced in the USA. Its price ranges from five hundred to a thousand rubles per pack. It is also based on clindamycin, is considered one of the most effective among other antifungal drugs. It has antibacterial characteristics that contribute to the elimination of the inflammatory process.
"Dalacin" is recommended for the treatment of arthritis in a purulent form, periodontal abscess, vaginosis, which are of bacterial origin. This drug is produced in such dosage forms as solution, suppositories, capsules, gel and ointment. Such a variety of forms of release is a definite plus. In addition, the gel is used as part of a comprehensive treatment for acne. Dalacin has a wide range of effects. Among the shortcomings, one can list the vacation of the drug exclusively by prescription, the inability to use during pregnancy and lactation.
Reviews
Reviews about the drug are mostly positive. Among its main advantages are the absence of allergies, ease of use, a really tangible effect after the first use. After a course of treatment, a repeated analysis shows the absence of signs of the disease, which indicates the effectiveness of the cream. In addition, it helps patients suffering from relapses of bacterial vaginosis. After using a large number of other drugs, for many of which there were allergic reactions, and the lack of a long-term result from their use, the effect of “Clindacin B Prolong” exceeds all expectations. It helps already at the initial stage of treatment, but the course must be carried out to the end in order to consolidate its positive effect.
Among the shortcomings is a rather high price. However, this drug really justifies the money spent. Of course, you must remember that before using Clindacin B Prolong, you need to consult a doctor who will determine the nature of the inflammation and prescribe the appropriate treatment.