To eliminate disorders of the microcirculation of the brain, their consequences, as well as neutralizing the symptoms of other organic pathological processes of the central nervous system, nootropics are widely used. Medicines that contain citicoline as an active ingredient. In most cases, they are prescribed by neurologists, since they are safe for the body and cause a minimum of side effects.
Vascular pathologies are the cause of most neurological diseases, which are manifested not only by impaired cognitive function, but can also lead to serious consequences. For prophylactic purposes, Citicoline can be used to prevent strokes, as well as eliminate residual effects after diseases. This is a medication that affects metabolic processes in the central nervous system.
What is included in the structure of the drug
Release form "Citicoline" - solution for parenteral administration. And also for oral use.
According to the annotation for use, it is known that Citicoline is a nootropic drug that is made in the form of a solution for parenteral use. Citicoline tablets and capsules do not exist.
What are the components? What is part of the drug? Citicoline contains the following substances:
- Citicoline Sodium.
- Hydrochloric acid.
- Caustic soda.
- Water.
When a medication is prescribed
According to the annotation for use, it is known that the drug "Citicoline" is recommended for use in the presence of certain pathological conditions. Indications for use of the drug "Citicoline":
- The acute stage of ischemic stroke (a violation of the microcirculation of blood in the brain with a violation of the tissue, as well as its functions).
- Cerebral infarction (a serious disease that is characterized by the death of brain tissue).
- Hemorrhagic stroke (a violation of the microcirculation of blood in the brain with a breakthrough of blood vessels, as well as hemorrhage in the brain).
- Cognitive and behavioral disorders.
- Traumatic brain injury.
- Amyotrophic lateral sclerosis (a disease that is accompanied by the death of central or peripheral motor neurons).
- Chorea (a pathological condition characterized by involuntary and chaotic movements of the legs and arms).
- Alzheimer's disease (complex lesions of the nervous system, which are characterized by loss of memory and logical thinking, as well as speech retardation).
- Parkinsonism (a neurological disease that is characterized by a number of signs: tremor, resistant increase in muscle tone, uniform muscle resistance, equally expressed in flexion and extension, as well as postural instability and slow motion).
- Dyscirculatory encephalopathy (a brain disease that occurs subsequently of a chronic progressive disturbance of microcirculation of the brain of various origins).
Does the drug have bans
According to the annotation for use, it is known that Citicoline is contraindicated in the presence of certain conditions. It:
- Severe vagotomy (a complex condition that is caused by an increased tone of the vagus nerve, which regulates the functioning of internal organs, as well as endocrine glands, capillaries).
- Breast-feeding.
- Age to 18 years.
- Increased sensitivity to any component of the drug.
With extreme caution, it is necessary to use the drug for a woman during pregnancy. And only in those situations where the likely benefits of therapy for the mother greatly exceed the threat to the fetus.
How to use the drug
According to the annotation for use, it is known that a solution for parenteral administration is used in a dosage depending on the indications. Intravenous injections are carried out for at least three minutes, it is better to infuse the drug drip at a rate of from forty to sixty drops per minute. The intramuscular method is used less frequently. With such injections, Citicoline must be administered to a new place each time.
In case of traumatic brain injury or ischemic stroke, one gram of the drug is administered every twelve hours immediately after the diagnosis has been made. Therapy should be carried out for at least a month and a half. If the patient has maintained normal swallowing function, it is necessary to switch to the oral form of the drug within three to five days after the start of treatment.
According to the annotation for use, it is known that during recovery it is recommended to use from 0.5 to 2 grams of the drug per day. The dosage regimen and duration of therapy are determined individually by a specialist.
Dose adjustment for persons of retirement age is not necessary. After opening the ampoule, its content must be used immediately. "Citicoline" can be mixed in one syringe or infusion system with all types of isotonic solutions.
Oral solution
Sachets of Citicoline can be diluted in water. Use the solution before meals or during it. As a rule, 200 to 300 milligrams of the drug is recommended for use three times a day. The duration of therapy is determined by a medical specialist.
Adverse reactions
According to the annotation for use, it is known that Citicoline very rarely provokes negative effects. But still they sometimes happen:
- Excitation.
- Hyperstimulation of the parasympathetic nervous system.
- Insomnia (sleep disturbance, which is characterized by superficial sleep, as well as a delay in its onset or early awakening).
- Hallucinations (an image that appears in the mind without an external stimulus).
- Vertigo (a disease better known as dizziness, it is characteristic of ear diseases or, less commonly, brain damage).
- Headache.
- Numbness in paralyzed limbs.
- Arterial hypotension (lowering blood pressure by more than twenty percent).
- Hypertension (a disease whose main symptom is an increase in blood pressure due to nervous and functional disorders).
What other adverse reactions does the drug cause
There are other adverse reactions. They are found less frequently. It:
- Itchy skin.
- Rashes.
- Hyperemia (a pathological process that is characterized by a local increase in the amount of blood in any tissue or organ).
- Purple (a disease that is characterized by small-spotted hemorrhages under the skin, in the epidermis or mucous membranes).
- Urticaria (a disease of allergic or toxic origin, which manifests itself in the form of spot spots - the main symptom is unpleasant itching).
- Anaphylactic shock (acute and severe allergic manifestations that occur as a result of repeated penetration of the allergen into the body).
- Dyspnea.
- Nausea.
- Loss of appetite.
- Vomiting.
- Diarrhea.
- Changes in the activity of liver enzymes.
- Chills.
If poisoning occurs, consult a doctor. He will prescribe symptomatic therapy.
Features
With intracranial bleeding, you can not use the drug in a dosage exceeding 1000 milligrams per day. Pour the solution intravenously slowly at a rate of thirty drops per minute.
According to reviews of Citicoline, it is known that people who drive vehicles need to be extremely careful during treatment. The drug can cause drowsiness, loss of coordination.
There is no exact information regarding the use of Citicoline in women during pregnancy. Despite the fact that studies of the negative effect of the drug were not detected, as mentioned above, during pregnancy it should be used only in situations where the likely benefits of therapy for the mother outweigh the threat to the unborn baby.
If necessary, treatment with "Citicoline" during lactation, breastfeeding should be stopped. Since there is no information about the safety of the drug.
For patients under the age of eighteen years, drug therapy is prohibited. Also, due to the lack of sufficient information that confirms the safety and effectiveness of treatment in children.
For patients of retirement age, individual dosing selection is not required. Citicoline can be combined with all types of intravenous isotonic solutions. You can not use immediately with drugs that contain meclofenoxate in the structure. "Citicoline" leads to increased action of levodopa.
Substitutes
Is it possible to replace the drug with something? Can. Analogs of Citicoline:
- Ceresil Canon.
- The Napilept.
- Neurocholine.
- Proneiro.
- Ceraxon.
- Rekognan.
- Noocil.
- Ronocyte.
- Quinel.
Before replacing the drug with one to another, you should consult a doctor. In order not to harm health.
How to store the medicine
According to the annotation for use, it is known that the drug "Citicoline" must be kept away from children, in a place protected from the sun, at a temperature of no higher than twenty-five degrees. Shelf life is 36 months. Prescription drug is dispensed. The cost of the drug varies from 900 to 1300 rubles.
Opinions of patients and doctors
Reviews about Citicoline (1000 mg) are usually positive. People note the increased effectiveness of drug therapy during recovery from stroke and traumatic brain injury, as well as in disorders that are associated with vascular lesions of the brain.
But there are also responses with complaints of adverse reactions. In many situations, such as dizziness, insomnia, migraine, agitation.
Most medical professionals leave good reviews about Citicoline. Noting the remarkable combination of a level of increased effectiveness and a very rare development of negative effects.
During the rehabilitation of people who have suffered a stroke, it is necessary to choose the right medicine to restore brain functions. Doctors often use Citicoline in their practice. In a medical facility, the drug is used in the form of injections, which allows you to quickly eliminate ischemia in the source of the lesion and neurological signs.
In addition, there are reviews of Citicoline (1000 mg), in which doctors narrate that patients with alcohol and drug addiction require the use of nootropic medications as an additional treatment. "Citicoline" helps to restore cognitive function, as well as memory and concentration.