In the article, we consider the instructions for use and price attached to the drug "Vilprafen Solutab"
To prevent serious complications from bacterial infections, doctors treat various antibiotics. Before prescribing the dosage of "Vilprafen Solutab", it is recommended to conduct an analysis to determine pathogenic bacteria. This drug is referred to as macrolide antibiotics. Subject to the correct dosages, a bacteriostatic effect on a wide range of different microorganisms occurs.
In increased concentration, the drug produces a bactericidal effect. "Vilprafen Solutab" shows activity against gram-negative and gram-positive bacteria. It does not affect enterobacteria, therefore its effect on the microflora of the digestive system is minimal. Resistance to the active substance is rare.
Description of the drug
The bacteriostatic effect of the drug is a violation of protein synthesis in the cells of microorganisms. According to the official instructions for Vilprafen Solutab, when using therapeutic concentrations of the drug, a significant slowdown in bacterial growth occurs, and at the same time, the reproduction of pathogenic organisms stops. Against the background of the creation of large concentrations in the foci of inflammation, a bactericidal effect occurs. The active substance of the drug - josamycin - has a selective effect on pathogenic organisms:
- The active component has bacteriostatic activity to various bacteria.
- It has an effect on the resistance of pathogenic bacteria.
- It has no bacteriostatic effect, showing resistance to enterobacteria.
- It has a slight effect on the microflora of the digestive system.
What else does the instruction manual for Vilprafen Solutab 1000 mg tell us?
The composition of the drug
The active substance of the drug is josamycin. Magnesium stearate along with silicon dioxide, aspartame, sodium docusate, hyprolose, microcrystalline cellulose and strawberry flavor are used as auxiliary ingredients to ensure its appearance along with ease of use. Many are interested in the instruction and price of Vilprafen Solutab.
Release form
This bacteriostatic antibiotic has only one type, that is, it is available only in soluble tablets, packaged in aluminum foil blisters. The tablets are oblong and white with a yellow tint. The taste of the pills is sweet, and the flavor is strawberry.
Pharmacodynamics and pharmacokinetics
When comparing "Vilprafen solutab" with other antibiotics of the macrolide category, it must be said that this agent is less likely to meet bacteria resistance to it. According to the attached instructions for use, this medicine is active against gram-positive, anaerobic and gram-negative bacteria, and this drug also copes with various intracellular microorganisms. Immediately after application with the active substance josamycin, the following occurs:
- The component is evenly distributed in tissues and organs, except for the brain.
- High concentrations of this substance are created in sweat, lungs, saliva and tonsils.
- There is a rapid absorption of the component from the digestive system.
- Metabolism occurs in the liver to a state of weakly active metabolites.
- Josamycin is excreted with bile and, to a small extent, with urine.
- The bioavailability of the component is independent of food intake.
- The substance accumulates in the bone tissue.
- May pass into breast milk.
- The active substance of the drug is able to penetrate the placental barrier.
Indications for use
The drug "Vilprafen Solutab" is recommended to be used when there is hypersensitivity to penicillin. Effectiveness is observed in the treatment of streptococcal infections, and in addition, in the treatment of mycoplasmosis. Indications for use are diseases of the ENT organs and the respiratory system as a whole.
Thus, "Vilprafen Solutab" 1000 mg is very effective for scarlet fever, diphtheria, sinusitis, laryngitis and tonsillitis.
In addition, this drug has proven effective in pharyngitis, otitis media, acute bronchitis, pneumonia, whooping cough and tonsillitis.
Doctors often prescribe this drug in the following cases:
- For infections of the oral cavity, for example, with alveolitis, periodontitis, pericoronitis, gingivitis and the like.
- Against the background of diseases of tissues and skin. For example, with panaritium, phlegmon, spherical acne, anthrax and furunculosis.
- Burn and postoperative infections.
- Against the background of pathologies of the digestive system, which are provoked by the helicobacter bacterium. For example, this drug is often prescribed for intestinal or stomach ulcers, and in addition, for chronic gastritis.
- Against the background of genitourinary infections, for example, with chlamydial or mycoplasma lesions, with syphilis, gonorrhea, urethritis, prostatitis, as well as for the treatment of venereal lymphogranulomas.
Contraindications
Contraindications to the use of the drug "Vilprafen Solutab" are the following diseases and conditions:
- The presence of high sensitivity to the components of the drug.
- The presence of impaired liver function.
- The weight of the child is less than ten kilograms.
- Prematurity of the child.
- The presence of a disorder of renal function.
- Lactation period.
Against the background of pregnancy, the use of "Vilprafen Solutab" should be careful and under the supervision of the attending physician. As practice shows, when used during pregnancy, if there is an urgent need, as well as subject to all recommendations, it is possible to get rid of one or another infectious disease, and such treatment does not affect the health of the unborn child.
The price of "Vilprafen Solutab 1000 mg" is of interest to many.
Dosage and administration
In order to properly use the medicine, you should first familiarize yourself with its instructions, which stipulates the dosage and duration of treatment for various diseases. The appointment in each specific situation is done by the doctor, taking into account the diagnosis and the general condition of the patient. The duration of the treatment course is usually from 5 to 25 days. This antibiotic is taken according to the following rules:
- The daily dose is up to 2 milligrams, and in the presence of a severe course of the disease, it increases to 3 milligrams.
- The entire amount of the drug is taken in two or three doses.
- In order to achieve the desired concentration, it is advisable to use the medicine in between meals.
- The tablet can be swallowed, and then washed down with a certain amount of liquid.
- As part of the preparation of the liquid composition, the tablet dissolves in a spoon of water, after which the medicine is thoroughly mixed.
- In order to fully recover, treatment breaks should not be taken.
Side effects and overdose
In accordance with the complete instructions for "Vilprafen solutab", an overdose is a common cause of side effects. If such cases occur, you must consult a doctor so that he changes the treatment regimen. Symptoms of an overdose are usually as follows:
- The development of pseudomembranous colitis.
- The appearance of hearing impairment.
- The occurrence of severe diarrhea.
- The development of dysbiosis along with a violation of the outflow of bile.
- The appearance of abdominal pain.
- The occurrence of Quincke edema along with vomiting, heartburn and jaundice.
- The appearance of urticaria, stomatitis or dermatitis.
special instructions
With regard to the use of Vilprafen Solutab, the instructions give special recommendations. So, when treating with this drug, the following should be considered:
- While taking this drug, it is quite possible to drive a car along with working on complex mechanisms.
- If there is a history of renal failure, control over the function of this organ is required along with the assessment of biochemical parameters.
- In the event that you have missed taking the drug, then the next time you need to take the usual dosage.
- Do not interrupt the treatment course.
During pregnancy
There is information that when using this antibiotic there is a possibility of its penetration through the placenta, and the active component of this drug may also get into mother’s milk. But, despite this, treatment with this bactericidal drug of chlamydial infections in nursing and pregnant women is allowed. But such a decision is made by the doctor, taking into account all contraindications for each specific patient. It is also necessary to evaluate what will do more harm - the use of the drug or the further development of the infection. But during lactation, against the background of treatment with this antibiotic, you need to stop feeding and transfer the baby to the mixture.
"Vilprafen Solutab" for children
It is especially important to observe the correct dosage when treating a child. This drug can be prescribed by a doctor only taking into account the weight of children. When treating children, the drug is dissolved in water to a state of suspension, which is very convenient during use, especially considering that this medicine has a pleasant smell and taste for the baby. The dosage is set in milligrams per kilogram of body weight. The use of this antibacterial drug is as follows:
- With a weight of up to ten kilograms, the dose should be 40 milligrams three times a day.
- With a weight of up to twenty kilograms, 250 milligrams are used twice.
- With a weight of up to forty kilograms, 500 milligrams are used twice a day.
- With a weight of more than forty kilograms, 1000 milligrams are used twice a day.
Drug interaction
Next, we consider the possibility of combining the drug with various medicines:
- When combined with hormonal contraceptives, their contraceptive effect is reduced.
- The drug "Vilprafen Solutab" significantly increases the level of cyclosporine in the blood.
- When combined with other antibiotics, the bactericidal effect of both decreases.
It should be borne in mind that taking josamycin together with various medications can change the results of treatment:
- The substance josamycin slows down the elimination of xanthines.
- When combined with ergot alkaloids, the lumen of the arteries narrows, which requires mandatory monitoring of the patient's condition.
- Antihistamines significantly increase the risk of arrhythmias that are incompatible with life.
- In combination with Lincomycin, the effectiveness of both drugs is reduced.
- In combination with Digoxin, the concentration of the latter in the blood plasma increases.
Alcohol interaction
In the case of the interaction of the antibiotic Vilprafen Solutab with ethanol, the following consequences are likely:
- With this combination, the digestive system is disrupted.
- There is an increase in toxic load on the liver.
- The effectiveness of the drug is reduced.
- There is a chance of cirrhosis.
- Vomiting is not excluded, along with dizziness, convulsions and fever.
- Lethal outcome is also possible.
This is confirmed by the instructions for use with Vilprafen Solutab.
Storage conditions
The presented drug is sold in pharmacies by prescription. During storage, the following recommendations should be observed:
- You can not use the drug after the expiration date, which is two years.
- It is necessary to contain the medicine in places where children cannot reach.
- Store the drug in a dry room, which should also be darkened.
- Storage temperature should not exceed 25 degrees.
Does Vilprafen Solutab have any analogues?
Drug Analogs
Not every patient can approach therapy with this drug, since it has contraindications, and in addition, side effects are possible. You can choose a replacement for this drug, but only a doctor should deal with this issue, since it is very important to take into account the patient's condition and correctly evaluate the course of the disease. Analogues of this medication are part of the macrolide group.
So, if it is necessary to replace Vilprafen Solutab, drugs in the form of Midecamycin, Roxithromycin, Clarithromycin, Azithromycin, Fromilidin, Chemomycin, Sumazid, Binoklara, Claritsina, and others will do. Klarbakta "," Erythromycin "," Azitral "," Rovamycin "and others:
- "Tsifran" - indications for use will be: otitis media, sinusitis, inflammation of the abdominal cavity, bacterial infections of the gastrointestinal tract, pelvic organs, gall bladder, kidneys, bones and joints, skin. Contraindicated in case of sensitivity to the drug, under 18 years of age, as well as during pregnancy and lactation.
- "Roxibel" - used for infections of the upper and lower respiratory tract, dermatitis suppuration, non-gonococcal urethritis. It is forbidden to people with cirrhosis, hepatitis C, allergies, also pregnant and lactating women, children under 12 years old.
Cost "Vilprafen Solutab 1000 mg"
The presented drug is referred to as potent drugs, it is dispensed in pharmacies by prescription. The cost of this medication directly depends on the number of tablets in the package, and in addition, on the trading margin of the selling company. You can choose a cheaper means of similar action. So, the average price for this antibiotic is 670 rubles per ten tablets at a dosage of 1000 milligrams.
Reviews about the drug
It is worth saying that "Vilprafen Solutab", according to reviews, today is a very popular antibiotic, which is preferred by many doctors. Patients, in turn, respond about him no less positively and are very pleased with the results of the treatment. Thus, you can hear a lot of positive and, at the same time, grateful reviews about the use of Vilprafen Solutab. It is also worth noting that, according to consumers' opinions, this antibiotic has high ratings, and many patients recommend it to others for treatment.
Parents are very pleased with the use of this drug, first of all, as it helps to avoid the need for injections for serious diseases in children. For example, Vilprafen Solutab effectively copes with purulent tonsillitis, and in this case, thanks to the convenient form of the drug, you can do without injections. Thus, parents are very pleased with the result of the use of soluble tablets and report that on the background of such treatment, the kids are quickly recovering. In addition, there is a pleasant taste and aroma of the drug, which children really like.
Pregnant women with chlamydia in the last stages of gestation are also pleased with the use of this antibiotic. Wilprafen Solutab is famous for its good reviews in the treatment of various diseases during this period. It is reported that, despite the position of the patients, the drug does not cause harm, the infection can be quickly dealt with, and children after this treatment are born completely healthy.
There are also positive reviews about the effectiveness of the drug in the treatment of exacerbation of bronchitis. Patients suffering from this disease like the fact that, unlike other medicines, this antibiotic has no effect on the gastric mucosa and does not provoke the development of dysbiosis.
Among other things, it is noted that, subject to the correct dosages and all medical recommendations, against the background of the use of this drug, no serious side effects are observed. In some reviews, there are only complaints of minor abdominal pain.
Thus, both doctors and patients consider the antibiotic to be very effective and effective. Parents of young children and women whom this drug saved from infectious diseases during pregnancy are particularly pleased with its use.
We have reviewed the instructions for use with Vilprafen Solutab 1000 mg.