If the segmented neutrophils in the blood are lowered, it is always a symptom of the development of a serious disease in the human body.
Neutrophil is a type of granular leukocyte, shaped blood element. It, unlike a red blood cell and a platelet that is not a cell, is a true highly specialized blood cell. The neutrophil nucleus is segmented, from which such a granular leukocyte is also called segmented. This nuclear segmentation helps the neutrophil to migrate through the tissues. Neutrophil has three to five such segments. Between themselves, they are connected by thin jumpers, and in the female body, chromatin is also observed during an electron diffraction, otherwise a drumstick. Such heterochromatin is spiralized, because synthetic processes are not visible in a mature cell. In addition to segmented neutrophil, there are immature neutrophils: young and stab.
If the electron diffraction pattern shows that the segmented neutrophils in the blood are lowered, this can signal the development of leukopenia (if less than 4 * 109 / l) or even neutropenia (if less than 1.8 * 109 / l). A decrease in the number of leukocytes to the level of 2-3 * 109 / l indicates the presence of infection in the human body. It can be infections like flu, paratyphoid B and A, rubella, typhoid fever, chicken pox, measles, hepatitis viral, polio, typhus, typhus, mumps, malaria, visceral leishmaniasis, ornithosis and others. If segmented neutrophils are reduced to the level of 1 * 109 / L and thrombocytopenia and anemic signs develop, these figures indicate acute leukemia, a deficiency of folic acid or vitamin B12, bone marrow metastases, aplastic anemia. The level of leukocytes in the blood decreases and in diseases such as thyrotoxicosis, diabetes mellitus, chronic cholecystitis, hypothyroidism, anaphylactic shock, duodenal ulcer or stomach ulcer, neurosis, collapse and others. Even if a person has simply increased (and significantly) physical exertion, he is in an excited state (emotional, psychological), hypothermia has occurred or pain has manifested itself, segmentophagous neutrophils may be lowered in the blood.
When segmented neutrophils are reduced in a child, this should alert the doctor. It is quite possible that an inflammatory process is going on in the child’s body, and a latent form of some dangerous disease is developing.
Neutrophil, like any granulocyte, has specific granules, but they are smaller. These granules contain special substances that contribute to the success of phagocytosis in the destruction of bacterial walls. Therefore, it is so important that the level of neutrophils is kept at a normal level, without decreasing or increasing. If the doctor, having received the results of a blood test, sees that the segmented neutrophils are increased or decreased, he again sends the patient for re-analysis. When the second sequential analysis confirms the results of the first, the patient should be referred to a hematologist for a consultation.
With an increase in the blood level of segmented neutrophils, neutrophilia develops. What diseases are characterized by such an increase in white blood cells? For intoxication, acute infectious disease, malignant neoplasm, that is, for those in which microbes are introduced into the human body, foreign substances, cell breakdown products accumulate. It can be infections, such as mycosis, bacterial or viral infection, as well as rickettsiosis, spirochetosis, tick-borne encephalitis and others. Possible increase in neutrophils in the blood of a person with the following inflammatory processes: gout, rheumatism, myositis, rheumatoid arthritis, ischemic necrosis, tissue damage, pancreatitis and many others. If a person has uremia, necrosis of liver cells, cancer, eclampsia, blood diseases, the level of neutrophils can also increase.
Neutrophils perform two functions in our body: bactericidal and phagocytic. An increase or decrease in their amount in the blood indicates that they cope successfully with these functions.