The drug "Ibuprofen" is indicated for rheumatoid arthritis, radiculitis, ankylosing spondylitis, gout, osteoarthritis, bursitis, myalgia, neuralgia. The drug is also prescribed for traumatic inflammation in the soft tissues, musculoskeletal system. As an auxiliary component , the Ibuprofen medicine instructions for use allow for use in headaches, toothaches, as well as in the complex treatment of adnexitis, diseases of ENT organs and proctitis.
A drug from the gastrointestinal tract is quickly absorbed. After one or two hours, the maximum level in plasma is reached, three hours in the synovial fluid.
The drug "Ibuprofen". Description
The drug has anti-inflammatory, analgesic and moderate antipyretic properties, due to the suppression of prostaglandin biosynthesis by inhibiting cyclooxygenase.
Take Ibuprofen tablets (each composition includes 200 mg of ibuprofen) is allowed no more than 2.4 grams per day. With rheumatoid arthritis, 800 mg is prescribed three times a day. With ankylosing spondylitis and osteoarthritis, 400-600 mg are recommended three or four times. For injuries in soft tissues, sprains, it is prescribed two to three times a day, 600 mg each. With rheumatoid arthritis (juvenile) "Ibuprofen", the instructions for use recommend 30-40 mg / kg of body weight per day. With moderate intensity of the pain syndrome, 400 mg three times a day is allowed.
The drug is ibuprofen. Instructions for use. Side effects
Taking the drug can cause anorexia, nausea, constipation, flatulence, diarrhea, heartburn, headache, dizziness, insomnia, agitation. Allergic reactions (skin rash), visual impairment are also likely . In medical practice, cases of the development in the gastrointestinal tract of erosive and ulcerative lesions were recorded. In rare cases, when taking the drug, bronchospasm, aseptic meningitis, bleeding from the digestive tract occur.
The drug is ibuprofen. Instructions for use. Contraindications
No medication is prescribed in the stages of aggravation in the gastrointestinal tract of erosive and ulcerative lesions, with the “aspirin triad”, ulcerative colitis, impaired hematopoiesis, severe disorders of the liver, kidney function, diseases of the optic nerve, individual intolerance to the drug, in childhood (up to six years).
The advisability of use during pregnancy is decided by the attending physician. The drug is not recommended in the third trimester. The drug "Ibuprofen" is able to inhibit the contraction of the uterine muscles. In addition, the drug can also contribute to blocking the hormones involved in the birth process.
When combined, the drug "Ibuprofen" has the property to reduce the diuretic effect of furasemide. The drug is able to enhance the effects of diphenin, hypoglycemic drugs for oral use (Glidiab), anticoagulants from the coumarin series (Warfarin).
An overdose of Ibuprofen is manifested by nausea, abdominal pain, vomiting, depression, drowsiness, lethargy, and tinnitus. Possible tachycardia, hypotension, renal failure (acute), bradycardia, respiratory arrest and atrial fibrillation.
To alleviate the condition, gastric lavage is performed (after taking the medication only within the first hour), the patient is given activated charcoal (to reduce absorption), as well as an alkaline drink. Forced diuresis is recommended, as well as symptomatic treatment.
Long-term use of the medication should be carried out under the control of renal and hepatic functions, a picture of peripheral circulation. Before using the drug "Ibuprofen" you should consult a doctor and carefully study the instructions.