In the article, we consider the instructions for use and reviews about it for the Cereton medication.
The medicine is a nootropic medicine that is used to restore the active functionality of nerve cells in the brain. The drug is a source of choline - a special substance that is involved in the production of the most important mediators of the central nervous system (for example, acetylcholine) and ensures the normalization of metabolic processes in the brain.
The composition of the drug and the form of release
According to the instructions for use, Cereton is made in the form of a solution intended for intramuscular or intravenous use, as well as in the form of capsules for oral administration. The main active ingredient in both pharmacological forms of the drug is choline alfoscerate.
As indicated by the instructions for use with Cereton in injections, intravenous and intramuscular solutions of the drug are a clear liquid that does not have color or smell, placed in 4 ml glass ampoules. 1 ml of such a solution contains 250 mg of the active component. Water for injection acts as an additional ingredient in the solution. One package of this medication may contain 10, 5 or 3 ampoules with a solution.
Cereton capsules consist of a soft yellowish gelatin shell, inside of which there is an oily solution with an active component content of 400 mg (choline alfoscerate), as well as additional substances - purified water and glycerol. The carton may contain 56, 42, 28 or 14 capsules.
Pharmacological properties
In accordance with the instructions for use with Cereton, the therapeutic effect of the drug is due to the characteristics of the active element. This medicine carries out the transport of choline to the central nervous system, where it is necessary for the production of acetylcholine (a substance that provides nerve impulses), as well as the production of such an element as phosphatidylcholine, which is a component of the cell membrane. As a result of this effect, the speed of conducting impulses along neurons increases, the elasticity of cell walls increases, brain cells and functions damaged during a certain pathological process of receptors are restored.
Against the background of the use of the pharmacological agent "Cereton" in the nervous system, the following reactions occur:
- improvement of cognitive processes;
- increased blood flow in the brain;
- restoration of blood circulation in the affected structures of the central nervous system;
- activation of metabolic reactions in the nervous system;
- restoration of the phospholipid composition of membranes and membranes of nerve cells;
- elimination of symptoms of neurological diseases;
- normalization of consciousness;
- improvement of cognitive functions and processes of memorization and assimilation of information;
- improving behavioral functions;
- restoration of the functional activity of receptors of the nervous system;
- normalization of processes of impulse transmission by neurons;
- improving memory, attention, concentration.
Pharmacokinetic features
According to the instructions for use, Cereton easily overcomes the blood-brain barrier. Its main concentration is observed in the cells of the brain, liver, and also in the tissues of the lungs.
Most of the active element of this medicine is removed from the body in the form of carbon dioxide by the lungs (80%), and the rest - with the help of the urinary system and with feces.
Indications for appointment
The pharmacological agent "Cereton" is prescribed for the following pathological conditions:
- Impaired attention.
- Dementia of unknown etiology, including senile.
- The consequences of traumatic brain injury.
- Violation of the functionality of the central nervous system of various origin.
- Attention disorder.
- Encephalopathies of various origins.
- The consequences of strokes.
- A variety of mental disorders that are organic in nature.
- Cerebral infarction.
- Violation of motor coordination.
- Intracranial hemorrhage.
- States of apathy, decreased motivation and mood.
Dosage regimen and method of application
What else can you learn from the instructions for use for "Cereton"? The duration of therapeutic treatment with a pharmacological agent is usually 6 months, especially when recovering from head injuries or strokes. In this case, the daily dosage is divided into two doses: in the morning, take 800 mg of the active substance (2 capsules), in the afternoon - an additional 400 mg. "Cereton" according to the instructions for use in the evening should not be used (at least 5-6 hours before bedtime).
With the development of dementia or cerebrovascular insufficiency of a chronic nature, the medicine should be taken 400 mg three times a day. The duration of the treatment course is determined by a specialist and can vary from 3 to 6 months. Instructions for use with Cereton tablets confirm this.
Solutions of this medication are used injected intramuscularly or intravenously in the acute stages of the development of pathological processes. The solution is recommended to be administered very slowly. The required dose is usually 1000 mg per day with a single injection. The duration of the therapeutic course is also determined by the attending doctor and is in the range from 10 to 14 days.
During pregnancy and lactation
The use of the pharmacological agent "Cereton" during lactation and pregnancy is contraindicated. If there is a need for such therapy during feeding, it is necessary to transfer the child to alternative types of nutrition.
Contraindications
The medicine “Cereton” has some contraindications for use. Their list includes:
- hemorrhagic stroke (in which cerebral hemorrhage occurs) in the acute stages of development;
- cases of individual intolerance to the main component of the drug or choline derivatives;
- age less than 18 years;
- pregnancy, lactation.
Side effects and symptoms of overdose
According to the instructions for use and reviews of “Cereton” in tablets and injections, the use of a drug with non-compliance with the dosage and administration regimens may lead to the occurrence of some side symptoms. In most cases, they are signs of dyspeptic disorder - nausea, bouts of vomiting. Among other negative reactions of the body to the effects of the drug are:
- cephalgia (headache);
- stool disorders (constipation or diarrhea);
- manifestations of pharyngitis (feeling of perspiration or foreign body in the throat);
- dry mouth
- sleep disturbance (daytime drowsiness, insomnia);
- dizziness;
- increased anxiety;
- manifestations of nervousness and aggression;
- skin rashes;
- increased urine formation.
With a substantial excess of the dosages recommended by the specialist, the manifestation of adverse reactions can significantly increase. In this case, disorders of the digestive system are most often noted. At the same time, the drug does not require withdrawal; dosage adjustment is possible.
Instructions for use with Cereton in injections and tablets are very detailed.
Special recommendations
Taking this pharmacological drug can provoke sleep disorders in the form of insomnia, as well as a state of nervous excitement. Therefore, it is recommended to take the medicine “Cereton” in the first half of the day (up to a maximum of 15.00).
According to the instructions for using this medication, you can combine taking with other medicines. Its pharmacological properties and features of pharmacokinetics with simultaneous therapy with other drugs are not changed. The only negative point is the simultaneous intake of intestinal sorbents, the particles of which bind the active components of the drug, as a result of which they do not have time to be absorbed into the bloodstream and the effectiveness of this drug is significantly reduced.
The use of the drug for patients whose work requires a high concentration of attention is allowed, since it does not adversely affect psychomotor activity. So it is said in the instructions for use to "Cereton" in tablets and injections.
Analogs
Choline alfaccerate is contained in other medications similar to the Ceterone drug. The list of such pharmacological agents includes:
- "Gleazer";
- "Cerepro";
- "Gliatilin";
- "Cholitilin";
- "Deletis".
We will not consider in detail instructions for use with Cereton analogues.
Reviews about the drug
Quite a lot of reviews about this pharmaceutical drug, however, among them there are both positive and negative. The opinions of patients were divided: some of them consider Cereton to be a very effective treatment for some neurological diseases, while others, on the contrary, did not notice a significant therapeutic effect from its use.
The positive reviews of patients reflect their opinion that the drug is well suited for the treatment of mental disorders such as depression, cognitive impairment, memory disorders and memorization of information. Patients indicate that the result is not immediately observed, and drug treatment should be long-term. They observed that after about a month of admission, they had normalized such functions of brain activity as concentration, increased attentiveness, improved mental and labor abilities, which significantly affected labor and educational activities. In general, this category of patients was satisfied with this medication.
Negative reviews about the drug contain information that this medication did not help people cope with their problems and they did not observe its significant effectiveness. In addition, in these reviews, patients indicated the occurrence of numerous body reactions to taking the drug, which in some cases required dose adjustment or discontinuation of the pharmacological drug. Among these phenomena, digestive disorders in the form of dyspeptic disorders, severe headaches, and dizziness were most often observed.
We considered the instructions for use, reviews and analogues for the Cereton medication.