"Combilipen" is a drug that is administered for acute neuralgic pains. This is a new generation multivitamin. It quickly and effectively eliminates pain. In an acute attack of neuralgia, an injection form of the drug is more often used. How to stab Combilipen? And how long is the course of therapy? We will consider these issues in the article.
Composition and action
Before you understand how to correctly inject Combilipen, you need to understand the composition and effect on the body of this drug. This combination medicine contains the following active ingredients:
- Vitamin B 1 (thiamine). This substance promotes faster transmission of impulses in the nervous tissue. It also has analgesic properties. Thiamine acts like anti-inflammatory non-steroid drugs, but is much milder. Vitamin B 1 normalizes the metabolism of fats and carbohydrates, and also slows down the aging of cells.
- Vitamin B 6 (pyridoxine). This component complements and enhances the action of thiamine. Pyridoxine has a positive effect on peripheral nerves and normalizes the production of neurotransmitters. Also, vitamin B 6 improves performance and improves memory.
- Vitamin B 12 (cyanocobalamin). This component strengthens the myelin sheath of nerve fibers. He is involved in the production of acetylcholine, a substance that improves the transmission of signals from neurons to muscles. In addition, cyanocobalamin stimulates the formation of red blood cells and prevents the development of anemia.
- Lidocaine. This is a local anesthetic that is often used in dental and surgical practice. When applied to the skin, lidocaine causes a loss of sensitivity. When introduced into the muscle, the anesthetic provides a pronounced analgesic effect. Also, this component contributes to better absorption of B vitamins.
It can be concluded that Combibipen is both a multivitamin complex and anesthetic. Vitamins improve the condition of peripheral nerves, and lidocaine relieves pain.
The drug contains very high doses of B vitamins. All of its active components complement and enhance the effect of each other. Therefore, the separate use of thiamine, pyridoxine and cyanocobalamin will not give the same strong analgesic effect. Conventional multivitamin complexes contain much lower doses of active substances.
Solution for injections and tablets
The drug is released in the form of a solution for injections and tablets. In addition to the active components, the injection form contains benzyl alcohol, water, caustic soda, potassium iron-sulphide, as well as the stabilizer E451. The solution has a pinkish color. It is packaged in 2 ml ampoules.
The tablet form is marketed under the trade name "Combilipen Tabs". It contains only a complex of B vitamins. Tablets contain twice as much pyridoxine as a solution for injections. However, lidocaine is absent in their composition; therefore, they have a less pronounced analgesic effect. The tablet form is used primarily for maintenance therapy.
How much can you stab Combilipen? This question is often asked by patients. Typically, injections are prescribed at the first stage of treatment, when it is necessary to stop the pain syndrome. The course of injections continues until acute pain disappears. As soon as the patient's condition improves, doctors recommend switching to the tablet form of this medication.
Indications
In what cases is it necessary to prick "Combilipen"? How to use this pain medication? The drug contains high doses of active ingredients. Therefore, it can be administered only for strict medical reasons and under the supervision of a physician.
The injection form of the drug is used to relieve pain in the following neurological pathologies:
- radiculitis;
- sciatica;
- diseases of the spine (including osteochondrosis);
- facial neuralgia;
- polyneuropathies of various etiologies;
- lumbar, cervicobrachial and radicular syndromes;
- intercostal neuralgia;
- nocturnal cramps of the calf muscles.
Tablets "Combilipen Tabs" have the same indications for use. But they are used after removing acute manifestations of pathology. In addition, the tablet form is prescribed for the relief of pain with herpes zoster.
Contraindications
Before stabbing "Combilipen", you must make sure that there are no contraindications to the use of this medication. This drug should not be used by people who are allergic to B vitamins and lidocaine. Otherwise, after the injection, negative reactions may occur. Also, the medicine is contraindicated in patients with pathologies of the heart and blood vessels, including with vegetovascular dystonia.
This drug is not allowed to be prescribed during pregnancy and lactation. Its active ingredients enter the milk and also cross the placenta. Huge doses of B vitamins and anesthetic can cause fetal development disorders. If the active substances have passed into breast milk, then they can provoke a sharp deterioration in the well-being of the baby.
How to stab Combilipen for children? This tool has limited use in pediatric practice, since benzyl alcohol is part of the injection solution. Very rarely, doctors prescribe this drug to adolescents over 12 years of age for the relief of neuralgic pains. The therapy is carried out under close medical supervision of the condition of the child. However, in most cases, doctors try not to prescribe this tool to patients under 18 years of age, since the effect of the drug on the emerging organism is not fully understood.
Unwanted effects
The use of the drug is rarely accompanied by the appearance of side effects. However, allergy sufferers may experience the following negative symptoms:
- itchy skin;
- rash;
- excessive sweating;
- anaphylactic shock (in severe cases).
In patients with vegetovascular dystonia or cardiac abnormalities, dizziness and tachycardia may occur after the injection. This is how the patient's body with weak vessels reacts to the administration of lidocaine. In such cases, the injection course should be discontinued and another drug for pain relief should be selected.
Often, patients independently inject themselves. How to inject Combilipen at home to avoid negative reactions? The first two injections are best done on an outpatient basis. After the injection, you must remain under the supervision of a doctor or nurse for 30 minutes. In this case, specialists will be able to provide the necessary assistance with anaphylactic shock or an allergy attack.
If after the first two injections there are no negative reactions, then in the future you can do injections yourself. However, if you are prone to allergies, doctors recommend that you take the entire course of therapy only in a treatment room.
Overdose
How many times to stab Combilipen during the day to prevent side effects? The dosage of the drug is selected by the doctor individually for each patient. However, even with severe pain, the daily dose of the drug should not exceed 4 ml.
Introducing excessive amounts of medication can cause intoxication. An excess of B vitamins and lidocaine negatively affects well-being. In this case, the following signs of an overdose occur:
- nausea and vomiting;
- tachycardia attack;
- dizziness;
- fainting condition;
- fever;
- excessive sweating;
- confusion.
If after the injection the patient has a similar symptomatology, it is urgent to call a doctor or emergency team. Gastric lavage and taking sorbents in this case will not help, since the drug is injected and immediately enters the bloodstream.
Recommended dosage
How often can you stab Combilipen? The drug effectively eliminates discomfort, but this does not mean that it can be administered with every pain attack during the day. Most often, doctors prescribe 2 ml of the drug (1 ampoule) 1 time per day. This is usually enough to stop the pain.
In especially severe cases, with the permission of a doctor, the frequency of injections can be increased up to 2 times a day. Such a daily dosage (4 ml) is the maximum allowable. In no case should it be exceeded, this can lead to serious intoxication.
The drug is also prescribed for the prevention of exacerbations in chronic pathologies of peripheral nerves. This helps to improve the condition of nerve fibers and prevent the re-development of pain.
How often can Combilipen be injected for preventive purposes? To prevent exacerbation of the pathology, it is enough to introduce 2 ml of the drug once every 2-3 weeks. During the period of remission, more frequent use of the drug is not required.
Introduction rules
The drug is allowed to be administered only intramuscularly. How to stab “Combilipen”, observing all the rules? The injection should be injected deep enough into the muscle. It is necessary to mentally divide the buttock area into 4 squares, and make an injection into the outer upper part. Before injection, the skin must be disinfected. The needle should enter the muscle tissue at least 2/3 of its length.
If the patient makes injections on his own, then it is allowed to inject the drug into the upper third of the leg. This area contains few blood vessels and nerve endings. Therefore, even an inexperienced person is unlikely to be able to harm himself with an inept injection.
In this case, it is very important to introduce the medicine to a sufficient depth. Otherwise, the solution will accumulate under the skin or in fatty tissue. This can lead to edema, the appearance of a hematoma and the lack of a therapeutic effect. After the injection, the injection site should be wiped with cotton soaked in an alcohol solution.
Therapy duration
Only a doctor can determine exactly how many days to inject Combilipen. It depends on the type of pathology, the severity of the patient's condition and the severity of the pain syndrome. In acute diseases, the course of injections takes from 5 to 10 days. In the future, the patient is transferred to maintenance therapy.
If within 10 days the treatment did not lead to a decrease in pain, then further use of the drug is impractical. In this case, Combilipen must be replaced with another medicine.
If the drug is used for prevention, then the duration of its use is determined by the attending physician. In this case, the medicine is administered once every few weeks, and an overdose is unlikely. Therefore, the preventive course can be quite long.
Possible treatment regimens
After the relief of acute pain, the patient is transferred to maintenance therapy. The following treatment regimens are used:
- The patient continues to receive injections of the drug "Combilipen", but much less often. Gradually, it is transferred to a preventive dose and 2 ml of the solution is administered once every 2-3 weeks.
- The injections are completely canceled and the drug "Combilipen Tabs" is prescribed. Tablets should be taken 1 piece after a meal 1 time per day. The course of treatment lasts 14 days.
Compatibility
How to stab Combilipen with other medicines? This tool is often used as part of complex therapy. However, a vitamin preparation is far from compatible with all medicines. It can not be administered simultaneously with the following drugs:
- other drugs with B vitamins;
- drugs based on adrenaline and norepinephrine;
- Parkinson's disease medication.
During the course of injections, it is necessary to abandon the use of alcohol. Ethanol significantly impairs the absorption of vitamins.
It should be remembered that the injection of the drug "Combilipen" can not be mixed in the same syringe with other drugs. This remedy is chemically incompatible with many medicines.
Joint use with "Diclofenac"
Is it possible to stab “Combilipen” and “Diclofenac” at the same time? These drugs are quite compatible and can be used as part of complex treatment. "Diclofenac" is an anti-inflammatory drug that has strong analgesic properties. Both drugs complement each other's action.
This combination of drugs is usually used for pain caused by an acute inflammatory process (for example, with radiculitis). In this case, it is important to remember that these two drugs must be collected in different syringes. With complex treatment, the dosage of the drug "Combilipen" remains the same as with monotherapy. Diclofenac injections are given once a day every other day.
How many prick "Combilipen" with "Diclofenac"? The course of combination therapy is carried out according to the following scheme:
- 1st day. Do one injection of each drug.
- 2nd day. Enter only "Combilipen".
- 3rd day. The drugs are used together, as on the first day.
Thus, the combined treatment lasts 3 days. Further, the course of therapy with a vitamin preparation is continued, and Diclofenac is canceled.
Combilipen and Midokalm: combination therapy
Combined treatment with Combilipen and Midokalm is often prescribed. These drugs belong to different pharmaceutical groups. "Midokalm" is a muscle relaxant that relaxes skeletal muscle. Such a combination of drugs is indicated for pain associated with muscle tension and stiffness, for example, with pinched nerves, osteochondrosis, spondylitis.
How often to stab Combilipen with Midokalm? To relieve pain, it is usually enough to do one injection of each drug per day. In this case, for each medicine, you need to use a separate syringe. In severe cases, injections of the drug "Midokalm" do twice a day. The course of combined treatment can take from 1 to 5 days.
Combilipen and Milgamma: which is more effective
Milgamma has the same composition as Combilipen. This product also contains B vitamins and lidocaine. These two drugs are never used together, since their combination can lead to hypervitaminosis and an overdose of lidocaine.
Patients are often interested in the question of which of the two drugs is better. Both drugs have the same list of indications and contraindications. Their composition includes the same active substances. These drugs differ only manufacturers. Combilipen is a domestic product, and Milgamma is available in Germany. By the effect on the body and effectiveness, these drugs are almost identical.
Conclusion
It can be concluded that the drug "Combilipen" is an effective analgesic. However, such a potent medicine can be used to stop pain only as directed by a doctor. It is very important to give injections correctly and not exceed the recommended dosage. This will help to avoid unpleasant side effects.