A healthy human body is a well-established system of interaction of its elements. And the atypicality of one of them entails a failure of the entire functional integrity. What role does uric acid play in human blood and what is the reason for the excess or decrease in the norm of its content?
The nutrition of the modern population is characterized by high-protein food. In the process of protein breakdown , nitrogenous compounds are formed in the body, the balance of which is maintained by their uninterrupted removal from the body. If uric acid in the blood is lowered, nitrogen can accumulate above the required rate, since it is with it that excess of this element is removed. However, its increased content, or hyperuricemia, is the main sign of gout of the primary and secondary form.
Uric acid in the blood is contained under the guise of a sodium salt, the concentration of which is due to the coordination of the processes of its synthesis in the liver and excretion through the kidneys.
Due to the intensification of synthesis and the slowing down of its excretion, salt crystals accumulate in the joints, kidneys, subcutaneous tissue and other organs.
Such diseases as leukemia, anemia due to a lack of vitamin B12, acute forms of certain infections (tuberculosis, pneumonia, scarlet fever), diseases of the biliary tract, liver, kidneys, diabetes, urticaria, chronic can indicate that uric acid in the blood is elevated. eczema, psoriasis, toxicosis during pregnancy, acidosis.
The analysis that is carried out for this diagnosis is a blood sampling from a vein, as well as a sample of synovial fluid, which is examined under a microscope for the presence of crystals. By X-ray, they can be detected only after a few years from the moment of illness.
Uric acid in human blood is formed as a result of eating foods high in purines, the decay product of which it is. So, you can adjust its indicator with the help of properly selected nutrition. If uric acid in the blood is elevated, a diet is a prerequisite, along with the adoption of drugs that inhibit its formation, as well as anti-inflammatory drugs.
Foods high in purines include meat of fatty varieties and internal organs, especially young animals and birds, meat broths, mushrooms, fish of fatty varieties and canned fish, legumes, beer, chocolate, coffee, tomatoes.
The most optimal food for removing sodium urate from the body is dairy products, citrus fruits and alkaline mineral waters.
If the indicator of sodium salts is brought to high limits, crystals deposited in the form of an acicular mass cause attacks of gout, which are transferred by a person quite painfully and with prolonged exposure lead to the destruction of bones and cartilage. Concentrating in the joints, crystals, first of all, are formed in the areas most distant from the heart with a low body temperature, and most importantly, mainly in the affected tissues. Thus, people with impaired protein metabolism should avoid injury (especially the lower extremities) if possible, so as not to provoke gout attacks in these areas.
The accumulation of such formations in the region of the kidneys makes it impossible to function to remove even a small dose of urate, which leads to the formation of stones and the need for surgical intervention.
Accompanying ways to alleviate the condition in such disorders is plasmapheresis and physiotherapy. It is necessary to reduce body weight, as well as treat other existing metabolic diseases.
It is not possible to completely cure gout, however, uric acid in the blood is perfectly controlled with an alkaline diet, thereby reducing the frequency and intensity of painful attacks. It is necessary to lead an active lifestyle, drink more fluids, and in particular, do not burden the body with heavy food before bedtime, during which oxidation processes mainly occur.