The drug Pefloxacin is a very strong antibiotic that can cure a large number of serious diseases, for example, gonorrhea, cystitis, pyelonephritis, prostatitis, etc. This product is not available for sale, to get it, you need a prescription from a doctor. Today we will tell you all about Pefloxacin. Instructions for use, composition, contraindications, reviews of people who took it are presented in this article. We also consider the drugs that can replace this medication, and briefly describe them.
Description
Pefloxacin is a broad-spectrum antibiotic. It belongs to the group of fluoroquinolones.
The active substance of this antibiotic is the same name as the drug itself - pefloxacin.
A medicine is produced in Ukraine, in Russia.
Indications for use
Means "Pefloxacin", the instructions for use of which must be included in the package, can be prescribed for such problems:
- Infections of ENT organs.
- Damage to the pharynx, larynx.
- Skin infections.
- Sepsis, bacterial endocarditis.
- Salmonellosis.
- Typhoid fever.
- Prostatitis.
- Gonorrhea.
- Chlamydia.
- Cholecystitis.
- Infections of the organ of vision.
- Staphylococcal meningitis.
- Infections of bones, joints.
- Damage to the middle ear.
- Urinary tract infections, etc.
Release form
The medicine "Pefloxacin", the instruction for which is quite voluminous, is implemented in two forms. This is a pill and solution for infusion.
Instructions for use of tablets
The medication in this form of release is used only for uncomplicated infectious ailments. Usually tablets are taken 2 times a day, 400 mg each. Do not chew pills. They need to drink plenty of water. It is advisable to take tablets on an empty stomach. If necessary, the doctor can increase the dose to 1600 mg per day.
The medicine "Pefloxacin": instructions for use of the solution
An agent is administered in this form of intravenous drip. The dosage is selected individually, it depends on the severity of the disease:
- For infections that did not cause complications, 400 mg twice a day.
- With sepsis, infectious endocarditis, severe infections - 800 mg (first dose), then 400 mg every 12 hours.
The drug is administered within 1 hour. Before infusion, the contents of the ampoule must be diluted with a glucose solution.
The average duration of treatment is 2 weeks.
Adverse reactions
The medicine "Pefloxacin", the instructions for use of which must be read by the patient, can entail the appearance of such side effects:
- From the nervous system: dizziness, headaches, depression, fatigue, anxiety, emotional arousal.
- From the digestive tract: flatulence, nausea, vomiting, hepatic necrosis, hepatitis, diarrhea, abdominal pain, cholestatic jaundice.
- From the urinary system: dysuria, crystalluria, glomerulonephritis.
- Other reactions: skin rashes, candidiasis, itching, Quincke's edema, tachycardia, myalgia, tendon rupture, phlebitis, bronchospasm, tendonitis, neutropenia, arthralgia, etc.
Limitations
The antibiotic Pefloxacin is prohibited to use in such cases:
- If a person has an increased sensitivity to the components of the drug.
- With epilepsy.
- Pregnant women.
- To mothers who breastfeed babies.
- Children under 15 years.
Storage conditions
"Pefloxacin" - tablets distributed only to those people who will bring a prescription from a doctor with the signature and seal of a specialist. This antibiotic should be stored in a dry place, away from the sun. Also, it must be hidden from the kids so that they do not inadvertently find a pill or solution and take them inside. After all, this is a serious drug that can have a detrimental effect on the children's body.
The temperature at which the product can be stored is from 15 to 25 degrees.
The shelf life of the pills is 3 years, and the solution is 2 years.
Substitutes
The medicine "Pefloxacin" has analogues, and there are many of them. So, among the drugs that this medicine can be replaced with are the following: Zanocin, Lomefloxacin, Lomflox, Tsiprobay. These medicines are used to treat the same diseases, however, the active substances they have are different, not like those in Pefloxacin tablets.
Synonyms for this drug, or in other words generics, also exist. So, medicines that have the same active substance, but are available under different brand names, are such funds: Pefloxacin-AKOS, Peflacin, Perti, Pelox-400, Unikpef, Abaktal , "Perflox", "Peflatsin."
Assessments of people and doctors
The medicine "Pefloxacin" reviews is mostly positive. True, the number of responses is actually small. And people only post pills on forums, not injections. Patients note that, in general, the drug is well tolerated. It effectively fights pathogens of various infectious diseases. But some patients are unhappy with these pills because pills often cause side effects in the form of nausea, weakness, bitterness in the mouth.
Doctors respond positively about this medication. They declare that the Pefloxacin remedy, the analogues of which are inferior in effect to this drug, is doing its job. Doctors are 100% confident in this medication and consider it one of the best in their niche. True, in pharmacies, pharmacists often offer its counterpart - the tool "Abaktal". This drug is known to many people due to the excellent marketing work of the manufacturer of these pills.
The drug "Abaktal"
It is also an antimicrobial agent with a bactericidal effect. The medicine is prescribed for problems such as gonorrhea, chlamydia, sinusitis, meningitis, endocarditis, salmonellosis, typhoid fever, cholera, paratyphoid, orchitis, chronic pyelonephritis, cystitis.
Side effects after treatment with this drug can be the following: nausea, abdominal pain, loss of appetite, hepatitis, jaundice, headache, insomnia, depression, fatigue, irritability, urticaria, bronchospasm, angioedema, tachycardia, myalgia, tendonitis, etc.
A prescription is dispensed.
Opinions of people about the drug "Abaktal"
There are few reviews on this drug on the Internet. Despite the fact that the medicine is used to treat various diseases, people speak of it as a good medicine in the treatment of cystitis and pyelonephritis. Pain during urination, general weakness, lower back discomfort, fever, nausea, vomiting - all these symptoms successfully stop the Abactal tablets. People note that even after one drunk pill, their health improves. And after 10 days, the ailment passes without a trace. This is a really powerful antibiotic that kills the entire microflora. Therefore, it is very important to take medicines in parallel with it, which can immediately normalize it. Despite the fact that the drug "Abaktal" receives positive assessments of patients, patients nevertheless note that it causes side effects. Often this is nausea, but there is also a headache, irritability.
Means "Pefloxacin-AKOS": description
The medicine is also available in the form of tablets, as well as a solution. The medicine "Pefloxacin-AKOS", the instructions for use of which are similar to the instructions for use of the described drug, are prescribed in the same dosage:
- For tablets - 400 mg 2 times a day. The daily dose is 800 g.
- With intravenous administration: the first dose is 800 mg, then 400 mg every 12 hours.
In case of impaired liver function, the patient undergoes a dosage regimen correction. So, with minor problems, 400 mg of the drug is prescribed per day. With obvious violations - after 36 hours. If the liver pathology is severe, then the interval between administrations is increased to 2 days.
Special instructions. Side effects
- The antibiotic Pefloxacin-AKOS needs to be washed down with a large amount of liquid.
- During treatment, it is forbidden to be in direct sunlight.
- It is necessary to refrain from classes that require increased concentration of attention.
The list of side effects of the drug "Pefloxacin AKOS" is extensive. But this is an antibiotic, and it kills all the microflora in the intestines. So, the possible negative manifestations of this medication are:
- Dizziness, insomnia, excessive fatigue, depression, anxiety, cramps.
- Crystalluria, glomerulonephritis, dysuria.
- Nausea, diarrhea, flatulence, anorexia, cholestatic jaundice, hepatitis, liver necrosis.
- Itching, rash on the body, Quincke's edema, bronchospasm.
- Candidiasis, tendon rupture, tachycardia, etc.
This is not a complete list of side effects, the list in the instructions is detailed. It can be seen right away that the drug is not harmless, so you need to take it only under the supervision of a doctor. In principle, it will not work differently, since the medicine is sold only by prescription. Therefore, it will be possible to take the drug only after the doctor examines the patient, diagnoses him and only then prescribes tablets or solution.
Reviews of people about the drug "Pefloxacin-AKOS"
Patients note that both tablets and injection are effective. The drug quickly helps relieve the symptoms of any disease that is prescribed in the instructions, and after a few days and eliminate the disease itself. Unfortunately, like any antibiotic, this medication often causes various undesirable reactions: diarrhea, nausea, headache, etc. People say that in general side effects need to be tolerated. Doctors say that if any adverse events occur, the doctor should be notified.
The drug "Zanocin"
This is another substitute for Pefloxacin. This drug has a different active substance, and it is ofloxacin. A medicine is also prescribed for various infections: gynecological, urinary, respiratory tract, organ of vision, skin, gastrointestinal tract. Also, this medication is used in the complex treatment of tuberculosis.
The drug is produced in the form of tablets, as well as an infusion solution.
The dosage of the drug must be selected individually.
Often tablets are prescribed as follows:
- For uncomplicated urinary tract infections - 1 pc. 2 times a day.
- Chlamydia - 1.5–2 pcs. twice a day for 10 days.
- Acute gonorrhea - 2 pcs. once.
- Prostatitis - 1.5 tablets twice a day.
Dosage for intravenous drip:
- Infections of the respiratory tract, tissues, skin: 200-400 mg twice a day.
- Urinary tract diseases: 200 mg 2 times a day.
The medicine "Zanocin" should be used with caution in patients who have disorders of the central nervous system (epilepsy, cerebral arteriosclerosis). Also, people who are undergoing therapy with this medication should take a large amount of water in order to prevent the development of crystalluria (the appearance of crystals in the urine). If a person has problems with the kidneys, then the dosage of the drug in this case is reduced. It also decreases if therapy is performed in relation to an elderly patient.
It is forbidden to prescribe tablets or Zanocin solution to pregnant women, children and adolescents.
Conclusion
From the article you learned a lot of useful information regarding the antibiotic Pefloxacin. The form of release, indications for use, possible side effects of the medication are now known to you. We also got acquainted with the analogues of this drug and realized that any remedy with antibacterial properties can cause a person some harm. However, such drugs completely kill the infection, relieve the problem in a few days. But during treatment with antibiotics such as Pefloxacin, Zanocin, Abactal, you must take medications that support the intestinal microflora.