In the article, we consider the instructions for use, analogues and reviews for the Prestarium tool.
It is an ACE inhibitor or angiotensin converting enzyme. It is prescribed to lower blood pressure. The most dangerous condition is for patients with heart failure. The medication allows you to maintain the patient's condition in normal. Reviews about the Prestarium are abundant.
Indications
There are several pathological conditions in which a “Prestarium” is prescribed. All these diseases are accompanied by a systemic increase in blood pressure. These include:
1. Arterial hypertension of the isolated type.
2. To reduce the risk of re-stroke caused by a sharp increase in blood pressure.
3. Prevention of complications from the cardiovascular system, which are associated with the formation of blood clots inside the vessels.
Another indication for the appointment of the drug is heart failure, wearing a chronic form. The drug can reduce the functional load on the heart by normalizing blood pressure. This is confirmed by the instruction. Reviews about the Prestarium are mostly positive.
Contraindications
There are a number of physiological and pathological conditions when taking is contraindicated. These conditions are:
1. Angioneurotic edema, caused earlier by taking the drug from the group of ACE inhibitors. It is expressed in the form of edema of various tissues, which is due to the increased permeability of the vascular walls as a result of an allergic reaction.
2. Angioneurotic edema of an idiopathic or genetically determined species.
3. The combination of drugs, which includes aliskiren. This is especially true for patients with renal failure or diabetes.
4. Lactase deficiency, glucose-galactose malabsorption, lactose intolerance, as well as other conditions associated with impaired absorption and digestion of lactose carbohydrate, which is part of the Prestarium.
5. The period of pregnancy and breastfeeding.
6. Individual intolerance to the components of the drug.
7. The age of the patient before the onset of 18 years, since the safety of admission for this category has not been established.
8. Reaction to other drugs from the group by an ACE inhibitor.
What else does the instructions for use with the Prestarium tell us? We will consider reviews below.
Careful reception
There are also a number of conditions in which the drug should be taken with caution. In particular, they include:
1. Bilateral stenosis of arteries in the kidneys.
2. The presence of one working kidney.
3. The pathology of connective tissue of a systemic nature, for example, with rheumatism, systemic lupus erythematosus, scleroderma, etc.
4. Reduced circulating blood volume caused by prolonged diarrhea, diuretic drugs, and blood loss.
5. Concomitant use with drugs that suppress the immune system.
6. Diabetes mellitus.
7. Thyroid disease.
8. Heart failure decompensated type.
9. Concomitant use with drugs related to potassium-sparing diuretics.
10. During the implementation of surgical procedures, hemodialysis, after a kidney transplant, with hypertrophic obstructive myocardiopathy, etc.
Before prescribing the drug, a specialist must check the patient for contraindications.
This confirms the instructions to the Prestarium tool. Reviews of analogues will also be presented.
Instruction manual
The standard dosage regimen is 1 tablet once a day. It is taken in the morning before meals. However, other dosages and modes of administration are possible, taking into account the nature of the disease and the condition of the patient:
1. For arterial hypertension, Prestarium is taken alone or as part of complex therapy. At the beginning of administration, 5 mg is prescribed. once a day, after that, if necessary, the dosage can be increased to 10 mg., which is the maximum allowable amount. For certain categories of patients, for example, with a reduced volume of circulating plasma, chronic heart failure, a concentration of basic mineral salts in plasma and over the age of 75 years, an initial dosage of 2.5 mg is allowed. in a day.
2. As part of the complex therapy of heart failure, which is accompanied by increased systemic blood pressure, 2.5 mg is prescribed. per day. Admission should be carried out under the supervision of a doctor. If necessary, the daily dosage may be increased to 5 mg.
3. In order to prevent re-stroke of the brain, Prestarium is prescribed in combination with Indapamide. At the initial stage, 2.5 mg is prescribed. per day, followed by an increase to 5 mg. When “Indapamide” is included in the treatment regimen, the amount of the drug decreases again.
The duration of taking "Prestarium" is determined by a specialist individually. In the vast majority of cases, it is necessary to take the drug for life.
Side effects
According to reviews of the Prestarium, a number of undesirable reactions from some systems and organs are possible. They are similar to adverse reactions that may appear while taking any drugs that are part of the ACE inhibitor group. Similar side effects include:
1. Digestive system: nausea and vomiting, pain in the abdomen, taste impairment, dry mouth, the inflammatory process in the pancreas or liver can rarely develop.
2. Central nervous system: paresthesia, characterized by loss of skin sensitivity, headache, dizziness, rarely there may be sleep disturbance, a sharp change in mood, confusion and fainting.
3. Cardiovascular system: a pronounced decrease in blood pressure, that is, hypotension, vascular inflammation in the form of vasculitis, increased heart rate (tachycardia). Myocardial infarction and cerebral stroke are also possible.
4. Respiratory system: shortness of breath, dry cough, bronchospasm, rarely eosinophilic pneumonia and rhinitis.
5. Urinary system: rarely, kidney failure is possible.
6. Genital system: impaired ejaculation and erection in men.
7. Musculoskeletal system: muscle cramps that are uncontrollable, myalgia in the form of muscle and joint pain.
8. Skin: itching and rash, urticaria, angioedema of the tissue under the skin, with frequent localization in the face.
9. Hypohydrosis, sensitivity of the skin to light.
10. Sense organs: tinnitus, visual impairment.
11. Circulatory system: an increase in the level of eosinophils, which belong to the part of the immune system that is responsible for the occurrence of allergies.
In addition, against the background of taking "Prestarium", according to reviews, a general condition deterioration may develop, which is accompanied by weakness, decreased performance, etc. If the above symptoms are observed when taking the drug, the attending physician must decide whether to cancel it or reduce the dosage.
Holidays in pharmacies
Prestarium is dispensed in pharmacies only by prescription. It can not be taken on its own without consulting a specialist and not having received an appointment. Otherwise, adverse reactions and undesirable complications may occur.
Reviews on the Prestarium
Patient reviews are mostly positive. Its speed is noted, almost immediately after the start of the intake, relief comes. The drug has proven particularly well in patients with chronic heart failure. Thanks to the drug, such patients can improve the quality of life and not endure many restrictions. What other reviews are there about Prestarium 10 mg?
Even when taking the drug and apparent relief, do not forget that excessive physical exertion should be excluded. They can adversely affect the state of the cardiovascular system. You can also not take the drug without prior consultation with a cardiologist. Only a specialist can assess the potential risk of complications and prescribe a dosage appropriate to the patient's condition. An ideal option is to take the drug under observation in a medical institution.
There are also negative reviews about the Prestarium. However, this is most often due to non-compliance with the doctor’s prescriptions and instructions for use. For example, if you take the drug with food, then the bioavailability of the active substance is significantly reduced. Therefore, the effect of the drug may not be at all.
Analogs of the Prestarium
Reviews confirm that similar products are no less effective. These include:
- Perindopril;
- "Perineva";
- "Akkupro";
- "Arentopres";
- Burlipril;
- "Hyper".
Reviews of analogues
The reviews are mostly positive. All means of this group normalize pressure very quickly and for a long time. Rarely cause side effects, well tolerated by the body.