What do patients say about Tizin Allergy? Reviews of the mentioned medication will be presented at the end of the article. From it you will learn about the form in which this product is made, how much it costs, what substances it contains and what properties it has.
Composition, description, form and packaging
Tizin Allergy nose drops are a homogeneous suspension of white color. The active substance of this medication is levocabastine hydrochloride. In addition to it, the composition of the drug also includes such additional ingredients as sodium hydrogen phosphate, propylene glycol, hypromellose, sodium monohydrate, polysorbate, benzalkonium chloride, purified water and edetate disodium.
Tizin Alergi drops, the instructions for which are enclosed in a cardboard box, are available in 10 ml vials. They are made of polyethylene and are also equipped with a sprayer (for ease of use) and a special protective cap.
Pharmacology
The drug "Tizin Allergy", the price of which is indicated below, is an antiallergic drug. According to the instructions, such drops have a direct effect on selective blockers of H1 receptors (histamine).
After applying the medication in a patient, almost all the symptoms of rhinitis that have an allergic origin disappear. Also, this drug eliminates itching and nasal discharge. In addition, it prevents sneezing attacks.
Few people know, but Tizin Alergi drops can be used not only for instillation into the nose, but also for the eyes. As a rule, in ophthalmic practice they are used for allergic conjunctivitis.
According to experts, the effect after applying this medication occurs in about 5 minutes and lasts for 12 hours.
Pharmacokinetics
With the intranasal administration of the drug (in an amount of 50 μg), about 30-35 μg of levocabastine is absorbed. Its maximum concentration in the blood is observed after approximately three hours.
The binding of the active substance to plasma proteins is about 55%. The main metabolite (acylglucuronide) of the drug is formed during glucuronidation.
The half-life of a substance such as levocabastine is 37-40 hours. It is excreted by the kidneys (mainly unchanged).
Indications
What is the purpose of using the Tizin Allergy medication? Reviews report that such drops are effective in allergic rhinitis and conjunctivitis. Also, this medication is prescribed for exacerbation of hay fever and rhinoconjunctival syndrome.
Contraindications
What contraindications should you know before using the Tizin Allergy medication? Reviews of doctors say that this drug should not be prescribed for patients with hypersensitivity to active and additional substances that are part of the drops.
Also, this drug is not used to treat children under 6 years of age.
With extreme caution, nasal and eye drops are recommended for older people and those suffering from kidney failure.
Drops "Tizin Alergi": instructions for use
How to use the drug in question? He is prescribed intranasally. Children over 6 years of age and adult patients are recommended to use 2 doses of the drug (i.e. 100 mcg) in each nasal passage twice a day.
The use of this medication must be continued until all signs of the disease have been resolved. With severe symptoms of the disease, the drug can be used four times a day.
Before using the medication, the patient is warned about the need to clear the nasal passages of existing secretions and take a deep breath (through the nose) during the treatment procedure.
Mode of application
How to instill the drug "Tizin Alergi"? The reviews say that before the first use of this tool, you must remove the protective cap, and then press the nozzle several times. As a result of such atomization, a cloud of “fog” should form in the air. Next, the nozzle should be inserted into the nasal passage and press. At the same time, inhalation through the nose is required.
Before the next use of drops, the bottle should be shaken thoroughly.
Side effects
Unfortunately, the drug in question quite often causes side effects. These include the following:
- nausea, drowsiness;
- dryness, discomfort at the injection site, burning;
- pain in the larynx and pharynx, cough, nosebleeds;
- swelling of the nasal mucosa, bronchospasm;
- tachycardia, allergic reactions;
- headaches, dizziness;
- fatigue, local short-term irritation;
- malaise.
Drug overdose
There have been no reports of an overdose of the drug in question. However, experts believe that with a casual intake of drops inside the patient, the following are possible: a decrease in blood pressure, a slight sedative effect and tachycardia.
To eliminate such symptoms, the victim must drink a large amount of water in order to accelerate the excretion of levocabastine by the kidneys.
Drug interaction
In clinical studies, the interaction of this drug with ethanol was not observed. Also, the enhanced effects of Diazepam were not detected with the simultaneous use of Tizin Alergi nasal drops in usual dosages.
The combination of this agent with "Erythromycin" and inhibitors of the isoenzymes of ketoconazole CYP3A4 does not affect the kinetic parameters of levocabastine.
The local interaction of this medication with other intranasal drugs has not been studied, with the exception of its interaction with Oxymetazoline. By the way, the latter reduces the (transient) absorption of Tizin Alergi nasal drops.
Special recommendations
The drug "Tizin Alergi" (the instruction of this medicine is required to read) does not have a pronounced sedative effect, and also does not reduce the speed of the reaction.
If drowsiness occurs, the patient is not recommended to engage in hazardous activities, as well as drive a car.
After the expiration date of the drug, it should not be thrown out or drained into wastewater. The drug must be placed in a bag and put in a garbage container.
Cost and analogues of medication
How much do Tizin Allergy drops cost? The price of this medication is not very high. You can buy it for 210-280 rubles.
As for analogues, there are not very many of them. Similar actions are possessed by such drugs as Vizin Alergi, Histimet, Levocabastine, Reactin. However, they should be replaced with the Tizin Alergi drug only after consulting a doctor.
Reviews about the drug
Most patients who have ever used this drug leave only positive reviews about it. They report that this drug performs well when symptoms of allergic rhinitis and allergic conjunctivitis occur.
After using this medication in patients, nose discharge almost immediately stops. In addition, this drug prevents sneezing.
As for the minuses, they include the impossibility of using drops during pregnancy and during breastfeeding. Also, many people complain that this drug should not be used for children under six years of age.