The drug "Polydex" (spray for the nose) describes the instructions for use as a combined preparation used locally in otorhinolaryngology.
One milliliter contains ten milligrams of neomycin sulfate, 10.000 PIECES of polymyxin B, two hundred and fifty micrograms of dexamethasone sodium metasulfobenzoate and two and a half milligrams of phenylephrine hydrochloride.
Additional components are methyl paraben, lithium chloride, citric acid, lithium hydroxide, macrogol 4000, polysorbate 80 and purified water.
It goes on sale in plastic bottles of fifteen milliliters. Each of them is equipped with a special spray and placed in a cardboard box.
The therapeutic effect of the medication in question is achieved due to the anti-inflammatory effect exerted by dexamethasone (the active active ingredient). In addition, the antibiotics polymyxin B and neomycin, which are part of the drug, actively eliminate bacteria.
The pharmaceutical agent "Polydex" (nasal spray), the instruction contains this information, does not have a systemic effect.
Dexamethasone eliminates inflammation on the nasal mucosa, phenylephrine contributes to vasoconstriction. Due to the presence of the above antibiotics, the spectrum of the antibacterial effect of the drug on most of the gram-negative and gram-positive pathogenic microorganisms that cause infectious and inflammatory diseases localized in the nasal cavity and sinuses is expanding significantly.
Data on the pharmacokinetics of the drug in question are not available. Appropriate studies have not been conducted due to the low systemic absorption of the drug "Polydex" (spray for the nose).
The instructions for use prescribe the use of this medication for the treatment of rhinitis in acute or chronic form, sinusitis, rhinopharyngitis and other inflammatory and infectious diseases of the nasal cavity, sinuses.
The drug is available in the form of ear drops and nasal spray.
Instructions for use of the drug "Polydex"
One injection is shown in the nose (in each nostril) three to five times during the day. The duration of treatment can be from five to ten days. It is noted that children aged two and a half to fifteen years should be given a maximum of three injections per day. The duration of therapy is similar.
The pharmaceutical drug "Polydex" (nasal spray), patient reviews confirm this, can cause the development of local allergic reactions.
The medication in question is contraindicated in patients with hypersensitivity, suspected angle-closure glaucoma, the simultaneous use of MAO inhibitors, kidney diseases (accompanied by albuminuria), as well as if the patient has not reached the age of two and a half years.
During the period of gestation and breastfeeding, this drug is not prescribed. This is explained by the fact that the necessary clinical studies on the safety of its use for this category of persons have not been conducted.
The drug "Polydex" (spray for the nose), instructions for use informs, does not undesirably interact with other pharmaceutical preparations.
The structural analogue for the main active component is the drug "Maxitrol".
The medication in question is not used for washing the sinuses. With extreme caution, it is prescribed to patients suffering from hyperthyroidism, coronary heart disease and arterial hypertension.
To purchase this drug requires a doctor's prescription.