Medicines against fungal disease have long flooded the pharmaceutical market. This is due to the fact that damage to the nail plate and skin of any origin is difficult to treat. Fungal disease causes damage to the epidermis. In addition, with weakened immunity, the infection can spread to the internal organs, also affecting the respiratory, urinary systems and organs of the abdominal cavity.
Symptoms of the disease
Infectious damage to the nail is manifested by the following symptoms:
- shade change;
- nail compaction;
- the appearance of roughness on its surface;
- the appearance of spots;
- itching
- redness of the epidermis around the nail;
- peeling of the skin around the plate;
- dryness;
- fragility of nails.
Medicines for fungal infections are effective under the following conditions:
- Proper dosing.
- The use of the medication during the prescribed period of time by the doctor. That is, if the doctor recommends taking the drug 5 days twice a day, it means that way, and not otherwise.
- The use of the drug is exactly the company that the doctor prescribed. Since the doctor who prescribed the medication knows what to expect from this remedy, and how it shows itself in therapy.
- Compliance with personal hygiene.
The best pills for fungus on toenails
List of medicines:
- "Terbinafine".
- "Fluconazole".
- Lamisil.
- "Itraconazole".
- Ketoconazole.
- Orungal.
What pills for toenail fungus are best taken?
"Terbinafine"
An antimycotic drug that has a pathogenic effect on fungi of the genus Trichophyton, Microsporia, Epidermophytia. "Terbinafine" destroys the outer membrane of the source of the fungus, which helps to disrupt its functioning and leads to gradual death.
According to reviews, these are the best tablets against toenail fungus. The cost of the drug varies from 170 to 700 rubles. The drug is recommended for use in the following conditions:
- fungal infections of unknown origin;
- complex treatment of ringworm;
- dermatophytosis (the collective name that characterizes the group of fungal skin lesions);
- fungal infection of the feet;
- fungal damage to internal organs.
Side effects from the use of "Terbinafine" include:
- urticaria (skin lesion, which is characterized by the appearance of an itchy rash);
- anaphylactic shock (allergic manifestations of an immediate type, a state of sharply increased body sensitivity);
- Quincke's edema (reaction to the influence of various factors, often having an allergic origin);
- mental disorders;
- dizziness;
- violation of taste perception;
- exacerbation of inflammation in the joints and ligaments.
All these negative reactions are most pronounced when using the maximum allowable daily dose. The restrictions include:
- allergic reactions;
- failure of the kidneys and liver.
During pregnancy, tablets are contraindicated for use. Perhaps the use of "Terbinafine" in the last three months of waiting for offspring.
The method of application depends on the clinical picture of the disease and the severity of the manifestation of its symptoms. For adult patients, therapy is prescribed with a minimum dose of 250 milligrams per day. With treatment failure, the concentration of the drug rises by 2 times or the antimycotic agent changes. The duration of therapy varies from 14 to 180 days.
"Fluconazole"
These are inexpensive pills for toenail fungus. The cost of the drug varies from 40 to 270 rubles. The following conditions are indications for taking the drug:
- cryptococcosis (an infectious disease caused by yeast fungi, characterized by damage to the central nervous system, lungs);
- candidiasis (a group of lesions that are manifested by purulent secretions provoked by yeast-like fungi of the genus Candida);
- dermatomycosis (a condition related to a large group of fungal diseases affecting the skin, nails, folds of the body);
- multi-colored lichen (a type of mycotic diseases in which the parasite damages the stratum corneum of the dermis);
- Zhiber versicolor (acute dermatological disease, characterized by the appearance of pink spots on the skin of the trunk and extremities located along the lines of Langer).
These are some of the best pills against toenail fungus. The severity of side effects depends on the dosage and method of administration of the drug into the body. The following adverse reactions are likely to occur:
- itching of the skin;
- pain in the gastrointestinal tract;
- non-specific inflammatory lesions in the organs of the stomach and intestines.
Restrictions on the use of tablets:
- allergic reaction;
- liver failure;
- signs of viral hepatitis;
- renal failure;
- psoriasis (chronic non-infectious disease, dermatosis, affecting mainly the skin).
For fungal infections of the nails, 150 milligrams of tablets should be taken once a day for one month, after which 150 mg once a week (1 month), then as needed. Discontinue therapy after a healthy nail has grown.
The duration of treatment of fungal infection in young patients should be strictly calculated by a specialist depending on the severity of symptoms.
With the fungus of the nail plate and soft tissues, the drug can be used in a concentration of up to 12 milligrams per day per 1 kilogram of the child’s weight for one week.
Lamisil
An antimycotic drug, the active ingredient of which is terbinafine. Lamisil has a high pathogenic effect on sources of fungal infection not only of the skin and internal organs, but also of hair and nails. Even at low dosages, the drug has a detrimental effect on the outer shell of the fungus and provokes not only the suppression of its reproduction, but also gradual death.
Indications for use "Lamisil":
- fungal lesions of the nail plates;
- ringworm (damage to the skin, as well as human nails and hair, which is provoked by pathogenic fungi and is considered very contagious);
- onychomycosis (nail damage by fungal infection).
These are one of the most effective pills for toenail fungus. According to reviews and instructions for use, it is known that the adverse reactions that the drug exerts depend on the characteristics of the body and chronic diseases. The following conditions may occur:
- allergic manifestations of local and general nature;
- loss of appetite;
- migraine;
- dizziness;
- violations of taste buds.
The following conditions are a limitation to taking Lamisil:
- allergic reactions;
- kidney and liver diseases.
For adults, tablets are prescribed with a minimum concentration of 250 milligrams once a day for the treatment of toenail fungus. With damage to the nail plate, the duration of therapy depends on the effectiveness of the medication. If the symptoms of the disease are on the decline, then Lamisil should be taken until the stable disappearance of unpleasant symptoms.
Ketoconazole
A powerful antimycotic agent that is used to treat common fungal diseases. "Ketoconazole" destroys the sources of the fungus, affecting the protein structure of their outer shell.
According to reviews, tablets against toenail fungus are recommended for severe lesions that are caused by total damage to the plate and adjacent soft integuments.
The great advantage of this medication is that it affects the conditional and pathogenic bacteria, which, as a rule, exacerbate the clinical picture of the fungal disease and lead to a decrease in the effectiveness of some antimycotic drugs. The cost of the drug varies from 240 to 420 rubles.
Indications for use:
- infections caused by yeast-like fungi and damaging the mucous membranes;
- nail fungus;
- vaginal candidiasis (an infectious lesion that is provoked by yeast-like fungi and is characterized by the occurrence of irritation).
Side effects from the use of "Ketoconazole" depend on the concentration and duration of therapy:
- pain and discomfort in the abdomen;
- increased sensitivity of reflexes;
- vomiting and nausea;
- hair loss
- increase in body temperature;
- impotence;
- sleep loss
- conjunctivitis (an inflammatory lesion of the mucous membrane of the organs of vision that is triggered by an allergic reaction or infection);
- tonsillitis (an infectious disease, the leading sign of which is an acute or chronic inflammatory process in the tonsils);
- glossitis (pathological inflammation of the tissues of the tongue, which is more often a symptom of general pathologies of the body, but in rare cases acts as an independent disease).
According to the instructions, contraindications are:
- impaired renal function;
- children under 12 years old;
- impaired liver function;
- allergic reactions.
To use "Ketoconazole" during pregnancy is prohibited. The dosage and duration of therapy is determined only by the doctor.
Adults are prescribed 200 milligrams per day. With treatment failure, the concentration of the drug is increased by 2 times. In case of nail damage, the drug is consumed before the growth of a healthy plate, the duration of treatment is at least one month.
"Itraconazole"
An antifungal drug that has a powerful pathogenic effect on the source of infection. The price of the drug varies from 270 to 600 rubles.
According to the instructions for use of the drug, tablets against toenail fungus are prescribed in the presence of the following conditions:
- vulvovaginal candidiasis (the development of the inflammatory process on the mucous surfaces of the vagina caused by the activity of infectious microorganisms belonging to the fungi of the genus Candida);
- candidiasis of the oral mucosa;
- onychomycosis;
- histoplasmosis (an infectious disease, the source of which is the fungus Histoplasma capsulatum);
- sporotrichosis (chronic fungal infection of the body with typical skin manifestations);
- cryptococcal meningitis (a form of the disease in which the causative agent is a deadly fungus);
- paracoccidioidosis (deep systemic chronic mycosis, characterized by damage to the skin, as well as mucous membranes and internal organs with the formation of granulomas and ulcers).
From the instructions for use, adverse reactions are known that provoke Itraconazole:
- violation of the absorption of nutrients in the intestine;
- dysbiosis (a condition caused by a violation of the intestinal microflora associated with a change in the species composition of bacteria);
- pain and abdominal discomfort;
- migraine;
- dizziness;
- allergic manifestations.
Bans for the use of medicines:
- allergic reactions;
- kidney and liver diseases.
It is contraindicated to take Itraconazole during pregnancy and breastfeeding. Onychomycosis is eliminated by taking 200 milligrams of the drug per day for 3 months, then re-treatment is carried out.
Orungal
An antimycotic agent, which is produced in the form of capsules or solution. Prescribe the drug "Orungal" in the following conditions:
- pityriasis versicolor (a non-inflammatory disease of the skin of the fungal etiology that affects the stratum corneum of the epidermis);
- damage to the nail plate;
- deep visceral candidiasis;
- fungal keratitis (an inflammatory lesion that occurs in the cornea of the eye under the influence of pathogenic microflora);
- blastomycosis (a fungal disease in a temperate climate that usually occurs when in contact with soil, grass);
- paracoccidioidomycosis (systemic mycosis with the development of benign self-limiting pulmonary lesions);
- systemic aspergillosis (a disease caused by various types of molds and affecting several organ systems simultaneously);
- histoplasmosis.
Contraindications and side effects of Orungal
According to the instructions for use, the drug is not allowed to be used in the following conditions:
- breastfeeding;
- pregnancy
- increased sensitivity;
- in childhood and old age;
- cirrhosis of the liver (a pathological condition that is a consequence of impaired blood circulation in the system of hepatic vessels and dysfunction of the bile ducts);
- chronic diseases of the kidneys and heart.
When the nail plate on the legs is damaged, 200 milligrams are taken twice a day for one week. The duration of therapy is 21 days.
The drug is generally well tolerated. In rare cases, the following adverse reactions may occur:
- pain in the abdomen;
- diarrhea;
- intestinal obstruction;
- nausea;
- dyspepsia (a violation of the normal functioning of the stomach, difficult and painful digestion);
- gagging;
- hepatitis (inflammatory diseases of the liver, usually of viral origin);
- toxic liver damage;
- headache;
- peripheral neuropathy (damage to the conditionally allocated part of the peripheral nervous system);
- vertigo (the symptom most commonly known as dizziness, it occurs with an ear pathological process or brain damage);
- menstrual irregularities;
- pulmonary edema;
- congestive heart failure;
- itchy skin;
- rashes;
- alopecia (pathological hair loss, leading to their partial or complete disappearance in certain areas of the head or body);
- photosensitivity (skin reaction to sunlight with the participation of the immune system);
- Stevens-Johnson syndrome (acute allergic disease, which is characterized by rashes on the skin and mucous membranes).
Conclusion
Eliminate fungal damage to the nail plate is not difficult due to the large assortment of drugs. Many of them help get rid of an unpleasant disease in a matter of weeks.
The effectiveness of antimycotic drugs has been proven by numerous positive responses from people. It is important not to delay the therapy and immediately seek help from specialists when the first symptoms of the disease appear. The doctor will help you choose the most safe and effective medication.