Sandimmune neoral is taken so that there is no rejection of the transplanted organ, for example, the heart, liver, kidney, pancreas or lung. Also, this drug is prescribed for diseases such as acute non-infectious uveitis, when there is a threat of loss of vision, with chronic glomerulonephritis, which is accompanied by the development of nephrotic syndrome. Sandimmune neoral is also used in the treatment of rheumatoid arthritis with a high degree of activity, severe forms of atopic dermatitis and psoriasis.
Sandimmune neoral - instructions for use
Treatment with this drug should be carried out only in medical institutions by high-level specialists. They must have experience with immunosuppressive drugs. The use of sandimmune neoral requires constant monitoring of plasma creatinine levels. It is also necessary to constantly monitor blood pressure, the level of potassium in the blood is checked and monitored. During treatment, sandimmune neoral strongly contraindicated vaccination with any attenuated vaccines. After a course of treatment for three months and no positive results, you must stop using this drug and look for alternative ones. Only use glass containers during the preparation of the infusion solution.
Possible side effects
The use of this drug, like almost all others, can have side effects. This can be interstitial renal fibrosis, acute and chronic renal failure, seizures, paresthesia, impaired liver function, arterial hypertension, vomiting, nausea, abdominal pain, weakness, myopathy, pancreatitis, diarrhea, hypertrichosis, anemia, fluid retention in the body, hyperuricemia, gum hyperplasia, thrombocytopenia, headache, anorexia, and increased susceptibility to infections.
In some cases of overdose, muscle cramps and muscle weakness may appear, impaired vision and impaired consciousness.
In some patients, during an overdose of this drug, lymphoproliferative disorders appeared and the development of malignant neoplasms was noted, but this is a small percentage of all known cases.
Contraindications
There are a number of contraindications in which the use of the drug "Sandimmun" is strictly prohibited. The instruction necessarily gives a complete list of them. These are malignant neoplasms, hypersensitivity to the components that make up this drug, arterial hypertension, severe infectious diseases, hyperuricemia, various disorders in the functioning of the kidneys and liver, hyperkalemia, breast-feeding and pregnancy.
Overdose with Sandimmune
An overdose of the indicated drug may occur. Signs that indicate this will be drowsiness, tachycardia, vomiting and headaches, as well as severe renal failure. If the first signs of an overdose are detected, it is necessary to start gastric lavage and stimulate the appearance of vomiting in the patient, all this should be done immediately after taking the drug or within the first few hours. When more complex consequences occur, all vital functions of the body are supported, while dialysis and hemoperfusion with activated carbon do not bring results and are ineffective.
Capsules should be stored at a temperature that does not exceed 25 ° C, the solution - up to 30 ° C, but the bottle should be unopened. It is necessary to keep in places where the child cannot reach. Shelf life of Sandimmun is 3 years, and it is strictly forbidden to take the drug after it is over!