"Actovegin" is a medicine that has an antihypoxic effect. The drug stimulates the transport and assimilation by cells of various organs and tissues of oxygen and glucose.
As a result of the strong antihypoxic effect, Actovegin is also considered a universal accelerator of metabolism in all organs and tissues. The medication is used locally for the treatment of burns, abrasions, cuts, ulcers, bedsores, as it accelerates the healing of tissues.
In addition, Actovegin reduces the severity of disorders that are provoked by poor microcirculation of tissues and organs, and translates vascular diseases into milder forms, and also helps to improve memory and thinking.
Accordingly, in tablets and injections "Actovegin" is used to eliminate the effects of stroke. And also to eliminate circulatory problems. What reviews, analogues, price, instructions for use does Actovegin have?
Under the influence of the drug, tissue resistance to hypoxia increases, since it activates the process of utilization and oxygen supply. In addition, it triggers energy metabolism and glucose uptake.
Release form
According to the instructions for use, it is known that Actovegin is produced in the following forms:
- injection;
- solution for infusion;
- tablets;
- cream;
- gel;
- ophthalmic gel;
- ointment.
The composition of the drug includes deproteinized hemoderivative from calf blood. What does Actovegin treat?
When can I use the drug?
According to the instructions for use, it is known that the medication can be prescribed for many diseases.
Indications for the drug "Actovegin":
- Hemorrhagic stroke (acute violation of the microcirculation of the blood of the brain with hemorrhage).
- Encephalopathy (a non-inflammatory disease of the brain, as a rule, is congenital and acquired).
- Craniocerebral injuries.
- Ischemic stroke (a violation of microcirculation with damage to brain tissue, as a result of difficulty or stopping the flow of blood to one or another department).
- Angiopathy (a pathological process in the blood vessels that occurs as a result of impaired nervous regulation).
What does Actovegin treat? The drug is prescribed for the following conditions:
- Diabetic peripheral polyneuropathy (a disease that is considered a complication of diabetes and occurs when the glucose level is above normal).
- Trophic damage.
- Dementia (a persistent decrease in cognitive activity with the loss, to one degree or another, of previously acquired skills, knowledge and difficulty in the inability to obtain new ones).
- Wounds of different origin.
- Ulcerative skin lesions.
- Pressure ulcers (necrosis of soft tissues subsequently frequent pressure, which is accompanied by a violation of the microcirculation of blood and nervous trophism).
- Damage to the mucous membranes and skin that are caused by radiation damage.
- Radiation neuropathies (damage to the peripheral nerves, which is accompanied by a violation of their functioning).
"Actovegin" is prescribed to older people in order to avoid dementia.
Contraindications
According to the instructions for use, it is known that the restrictions on the use of Actovegin will be as follows:
- Oliguria (a pathological process in which the daily production of urine does not exceed 400 milliliters).
- Anuria (a disease in which urine does not enter the bladder, and, as a result, does not stand out from it).
- Decompensated heart failure (the terminal stage of the disease, which is considered the result of the fact that the affected heart muscle cannot transport blood to different systems of the human body).
- High sensitivity.
How to use the solution
According to the instructions for use, injections "Actovegin" intravenously can be used drip or jet.
Before the introduction of the drug, it must be dissolved in sodium chloride or in a five percent glucose solution. The permitted dosage of the drug is up to 2000 milligrams of dry matter per 250 milliliters of solution.
For intraarterial injections, Actovegin for adult patients should be used in a concentration of 5 to 20 ml per day.
Dosing with intramuscular injection cannot be more than 5 milliliters per day. In this situation, administration is slow.
After assessing the patient’s health, the necessary dosage is selected. The recommended concentration at the beginning of treatment varies from 5 to 10 ml intraarterially or intravenously. On the following days, the drug is injected into a vein of 5 milliliters or intramuscularly every day. Or several times during the week. Intramuscular injections are slow.
In severe condition of the patient, it is necessary to use "Actovegin" intravenously in a drop dosage of 20 to 50 ml per day for several days until improvement.
With exacerbation of various chronic diseases, which are characterized by moderate severity, it is necessary to administer the drug intramuscularly or intravenously at 5 to 20 milliliters. The course "Actovegin" varies from 14 to 17 days. Dose selection is carried out only by a doctor.
The frequency of use of the drug should be from one to three times. This amount varies depending on the condition of the patient.
In the treatment of patients suffering from diabetic polyneuropathy, it is better to start using Actovegin with intravenous administration. Dosage in this situation is 2 grams per day, the duration of therapy is 21 days. In the future, it is recommended to switch to tablets "Actovegin 200 mg" with a daily concentration of 2 to 3 pieces per day. The duration of therapy is 4 months.
Instructions for use of tablets
Use "Actovegin" in tablet form before eating, there is no need to chew it, you should drink it with water.
In most situations, one or two tablets are prescribed three times a day. The duration of therapy varies from 4 to 6 weeks.
Gel
What does Actovegin treat in this dosage form? The drug is applied topically to clean wound surfaces and ulcers, as well as their subsequent elimination.
If there is a burn or radiation injury on the skin, Actovegin should be distributed in a thin layer. With an ulcer, the medicine is applied in a thick layer and covered with a compress soaked in gel on top.
The dressing should be changed once a day, but if the ulcer gets wet, then this should be done more often. For patients with radiation injuries, Actovegin is applied in the form of applications. For the treatment and prevention of pressure sores, it is important to change the dressings three to four times a day. What does Actovegin treat?
Cream
Used to heal wounds, as well as weeping ulcers. In addition, Actovegin gel is used to prevent the occurrence of pressure sores.
For the treatment of radiation injuries, three times a day is prescribed. What is Actovegin ointment used for?
According to the instructions for use, the drug is indicated for the long-term treatment of ulcers and wounds, it is used after completion of gel or cream therapy.
Ointment "Actovegin" is applied to the affected area in the form of dressings, which must be replaced up to four times a day. If the drug is used to prevent pressure sores or radiation injuries, the compress should be changed three times a day.
Ointment for burns should be applied carefully so as not to damage the epidermis, for this the medicine is best applied first to the dressing.
Solution and tablets "Actovegin" during pregnancy for what purpose? The drug is not prohibited for use during an interesting situation. Why pregnant women are prescribed this medicine depends on the condition of the woman during the gestation of the baby.
As a rule, during this period it is recommended to women in position to prevent fetal development disorders in placental insufficiency.
In addition, the drug is sometimes prescribed when planning a pregnancy. Why are Actovegin tablets prescribed? For expectant mothers, a dropper, as well as injections or tablets with an interesting position, are prescribed to activate the uteroplacental microcirculation, stabilize the metabolic functions of the placenta.
In addition, the medication consists of natural substances, so it does not adversely affect the fetus, which is confirmed by the responses of women during pregnancy.
With an interesting situation, “Actovegin” solution is administered intravenously from 5 to 20 milliliters, the procedures are carried out daily or every other day. Intramuscularly, the drug is recommended to be used in an individual concentration, depending on what this medication is prescribed during pregnancy. Therapy usually lasts from 4 to 6 weeks.
What adverse reactions does the drug cause?
According to reviews, the drug in most cases is well tolerated by people. The following side effects of Actovegin can rarely be observed:
- Pain in the head.
- Vertigo (the condition most commonly known as dizziness, it manifests itself in diseases of the ears, brain damage).
- The appearance of tremors.
- Vomiting.
- Diarrhea.
- Pain in the abdomen.
- Soreness at the site of instillation.
- Nausea.
- Tachycardia (heart palpitations).
- Rashes on the body.
- Urticaria (a disease that is characterized by the occurrence of acutely itching, inflamed rashes on the epidermis, as well as mucous membranes).
- Itching of the skin.
- Angioedema edema (acute disease, which manifests itself in the form of local edema of the mucous membrane, as well as subcutaneous tissue and the skin itself).
In addition, there are a number of side effects from Actovegin, for example:
- Joint pain.
- Myalgia (a disease characterized by the development of muscle pain).
- Acrocyanosis (cyanotic color of the epidermis, which is associated with poor microcirculation of small capillaries).
- Decrease and increase in blood pressure.
- Soreness in the lumbar region.
- Paresthesia (one of the types of sensitivity disorder, which is characterized by a sharp appearing burning, tingling, crawling ants).
- Excitement.
- Suffocation.
- Hard breath.
- Pain in the larynx.
- Chest pressure sensation.
- Pain in the heart.
- Fever.
- Hyperhidrosis (a pathology that is accompanied by increased sweating throughout the body or only in certain areas).
Advice
The solution is considered hypertonic, so the introduction of the drug into the muscle should not exceed a dose of 5 milliliters.
There is a possibility of anaphylactic shock. To eliminate it, it is recommended to conduct a preliminary test for the perception of Actovegin by the body of a particular patient. For this, a sample of 2 milliliters of the solution is administered intramuscularly with further monitoring of the reactions.
With an interesting position and breastfeeding, a medication in the form of a solution can only be used according to strict indications. In pediatrics, injections are not prescribed.
Injections are compatible with glucose or sodium chloride. In addition to the above combinations, the drug should not be mixed with other drugs in the form of a solution, according to the instructions for use.
"Actovegin": analogues, price, reviews
The drug has certain substitutes, for example:
- Solcoseryl.
- Mexidol.
- Chimes.
- "Semax".
- Cortexin.
- Cavinton
- Omaron
- "Cerebrolysin".
- "Piracetam".
- Trental.
Before replacing the original drug with an analogue, you should get a specialist consultation.
The cost of the drug "Actovegin" varies from 500 to 1600 rubles.
Today there are many reviews of injections of Actovegin, in which patients narrate about the effectiveness in the treatment of various diseases. In certain situations, a significant improvement was noted in neurological diseases.
Some parents who used this medication for children, including infants, noted that it was difficult for their babies to tolerate the injections intramuscularly, since they are painful. Sometimes there was an allergy.
Responses about "Actovegin" with an interesting position of women leave good. In them they tell that after courses of intravenous or intramuscular injections it was possible to give birth to a completely healthy baby despite the threat of termination of pregnancy.
There are also reviews about Actovegin in tablet form. They are usually positive. Patients' opinions about ointments and gel indicate that both dosage forms and cream stimulate the healing of wounds and ulcers. The drug is convenient to use.
Which is better - "Actovegin" or "Solcoseryl"
The structure of the drug "Solcoseryl" includes the same active substance. But "Actovegin" has a longer shelf life because it contains a preservative. At the same time, experts note that substances that stop the growth of microorganisms in the product can adversely affect the human liver.
Cortexin or Actovegin
The first medicine is also of animal origin. But it is obtained from the cerebral cortex of piglets or calves. What is best prescribed in a particular situation, Cortexin or Actovegin, the doctor determines.
How to store the drug
According to the instructions for use, it is known that the Actovegin solution should be stored away from light at a temperature of no more than plus twenty-five degrees.
All types of medicine can be stored for 60 months, a solution for injections of 10% - 36 months. After the medicine in liquid form was opened and “Actovegin” was administered, it is impossible to leave the remains of the medication for the next procedure. Ampoules should be used immediately and do not store residues.