The drug "Acyclovir" (ointment), the instructions for use of which is in front of you, is a medicine that is used to treat various infections of the mucous membranes, skin integuments caused by the herpes simplex virus, herpes zoster. The medication is also used as a complex treatment of chickenpox. Acyclovir (eye ointment) is used to treat severe complications of herpes, which can affect the organs of vision. The drug has a pronounced antiviral effect.
Medication "Acyclovir". Release form, composition
The drug substance is produced mainly in the form of an ointment in tubes of aluminum, which are placed in packs of cardboard. One gram of the drug contains fifty milligrams of the active substance - acyclovir. Excipients of the drug are low molecular weight and high molecular weight polyethylene glycol.
Medication "Acyclovir" (ointment). Instructions: pharmacokinetics, pharmacodynamics
The drug, when applied topically, is not able to penetrate the bloodstream, its concentration in this tissue is negligible (0.01 mmol / L). The mechanism of action of the main component is a competitive interaction with the active substances of the virus (transaminase). The result is a phosphorylation reaction, the result of which is the formation of acyclovir phosphates. They are embedded in the DNA of the virus and suppress the processes of building up their genetic material. Such activity is manifested against the herpes simplex virus, herpes zoster, Epstein-Barr. The main substances of the drug prevent the formation of new morphological elements of the rash, reduce the likelihood of dissemination of the skin, visceral complications, accelerate the formation of crusts, and reduce pain in the acute phases of herpes zoster.
The drug "Acyclovir" (ointment). Instructions: method of application, doses
The drug is intended for external use only. It must be applied to the hearth five times during the day, observing an interval of four hours. Therapy should begin with the appearance of the first signs of the disease (first blisters, tension, itching). The course of treatment is ten days. The ointment is also applied to areas that border the skin affected by herpes.
Pharmaceutical agent "Acyclovir" (ointment). Side effects, contraindications
The drug has the following side effects: itching, burning, soreness, local irritation of the mucous membrane that disappears after drug withdrawal, as well as a skin rash, peeling of certain parts of the skin (with prolonged use, vulvitis may develop).
Among the main contraindications, hypersensitivity to individual components, pregnancy, lactation should be highlighted.
The drug "Acyclovir" (ointment). Instructions: drug interactions, special instructions
When taking the joint medication "Interferon" and "Acyclovir", the antiviral effect of the latter is significantly enhanced due to an increase in the rate of metabolic processes in the affected cells.
Ointment is recommended to be applied in rubberized gloves to prevent the possibility of infection in other areas.
During lactation, pregnancy, the drug should be used with extreme caution, and it is better to completely abandon its use. The drug does not have any effect on the ability to drive machinery, vehicles.
Medication "Acyclovir" (ointment). Instructions: overdose symptoms
When the dose is exceeded, characteristic clinical signs appear:
- headache;
- shortness of breath;
- neurological disorders;
- vomiting, nausea;
- renal function disorder;
diarrhea
- cramps;
- coma.
To eliminate them, hemodialysis is necessary.