"Akriderm GK" is a combination drug for external use in dermatology. The therapeutic effect of the drug is determined by the active active ingredients that make up its composition. According to the instructions, Akriderm GK has an anti-inflammatory, anti-allergic, antifungal and antimicrobial active effect.
- Betamethasone dipropionate has an anti-inflammatory, anti-allergic effect.
- The antibiotic gentamicin has a bactericidal effect and is active against pathogens of many infectious diseases.
- The antimycotic drug clotrimazole blocks the proliferation of the cell wall of fungi.
When using Akriderma GK in prescribed doses, the absorption of active substances into the bloodstream through the skin is insignificant (recommended for children from two years old).
Pharmacology
"Akriderm GK" is recognized as a local drug with several effects:
- anti-inflammatory
- anti-allergic
- antipruritic
- antifungal
- decongestant.
The mechanism of action of the drug is based on its ability to block the accumulation of leukocytes, on the release of pro-inflammatory biologically active substances in the inflammatory focus. Betamethasone, which is present in the composition of the medication, reduces vascular tissue ability and inhibits the formation of edema.
Gentamicin, which is part of the drug, is a well-known antibiotic of a wide spectrum of bactericidal effects.
Clotrimazole, which is part of the drug, is an antifungal agent from the group of imidazole derivatives. It acts by blocking the synthesis of ergosterol, which is an integral component of the cell fungal membrane.
Validity
With external use of the drug in therapeutic doses, the penetration of active substances into the blood is extremely insignificant. When applied to the skin, the penetration rate of the active ingredient, betamethasone, depends on the skin, its condition (absence of wounds and cracks). The use of dressings increases the absorption of betamethasone and gentamicin at times, which leads to an increased risk of developing negative effects.
Indications
According to the instructions for use of the Akriderm GK ointment, the drug is prescribed for the following diseases.
- Dermatitis, which is an acute inflammatory skin lesion resulting from the action of irritating factors of various etiologies on it.
- Diffuse neurodermatitis, which are skin diseases that have an allergic and neurogenic nature of origin. In the occurrence of neurodermatitis, a huge role is played by genetics, a predisposition to atypical reactions. Symptoms of the disease, as a rule, arise against the background of stresses or disorders in the activity of the nervous system. Disturbances in the digestive system and other mental disorders are essential. For diffuse neurodermatitis, the appearance of external symptoms is characteristic on huge skin integuments. In some cases, a rash and redness may cover the entire body of the patient.
- Limited neurodermatitis, including chronic lichen.
- Eczema, which is a skin disease accompanied by itching, the appearance of vesicles and pustules.
- Dermatomycoses (including thrush in women), which are fungal lesions of the skin, especially when they are localized in the groin or large folds of the skin (in women, mainly under the breast).
Dermatomycosis Treatment
When treating thrush, in addition to using Akriderma GK, systemic drugs are required to be drunk. "Akriderm GK" with thrush in women is used against the background of the recommended intake of other forms of antifungal agents taken orally. Dermatomycosis ointment is applied to the skin infected with harmful fungi. To achieve maximum effect, apply the cream once or twice a day in small quantities. You can rub the drug, but not necessarily. In men, thrush is located in the groin area. Preparations of other groups for thrush for men should also be taken. In this case, Akriderm GK acts as an additional local remedy. The main treatment is with systemic medications. The duration of thrush therapy depends on the speed of the drugs. With a mild form and a good effect from the treatment, you can limit yourself to five days, in a difficult case, you need to increase the course of treatment to two weeks.
You can start treating thrush with Akriderm GK only after the attending physician authorizes such therapy. There are forms of thrush, localized on the mucous membranes. With these forms of the disease, the use of "Akriderma GK" is irrational, since it is not recommended to be applied to the mucous membranes.
Pregnant women are not recommended to treat dermatomycosis with the help of Acriderma GC.
Contraindications
It is necessary to limit the use of Akriderm GK ointment in the presence of the following diseases:
- Lupus.
- Syphilis and its skin manifestations.
- Chicken pox.
- Herpes.
- Skin reactions after vaccination.
Side effects
According to the instructions, "Akriderm GK" can give a number of adverse reactions in the form of:
- Itching, severe burning or irritation, dry skin, folliculitis, hypertrichosis, the appearance of steroid acne, hypopigmentation.
- When using closed dressings, swelling of the upper layer of the skin, infection, atrophy of the skin is possible.
- With long-term therapy or application to large areas of the skin surface, an increase in the patient’s body weight, osteoporosis, increased pressure, the occurrence of edema, ulceration of the gastrointestinal mucosa, exacerbation of foci of infection, overexcitation, and frequent insomnia are possible.
Release form
Topical ointment "Akriderm GK" 15 or 30 g in tubes of aluminum. One tube is put in a pack.
Topical cream "Akriderm GK" 15 or 30 g in tubes of aluminum, one aluminum tube in a cardboard box.
If the patient’s skin is very dry, with many cracks and wounds, then they prefer to use ointment, and with a weeping lesion of the skin, use a cream. For a more even distribution, it is possible to mix the drug with a baby fat cream, however, mixing the cream and ointment will not work.
Dosage
According to the instructions for use, Akriderm GK must be applied externally. Patients are required to prevent the drug from getting into the eyes. It is not advisable to apply Akriderm GK to mucous membranes and large areas of the skin. The drug in any form should be applied in a small layer. Most often, the patient’s skin is lubricated twice a day. For example, at nine in the morning and in the evening at nine. At the first stage, a single application per day is sufficient, and if the disease is severely neglected, the attending physician may recommend a different dosage and frequency of use.
Cream or ointment is applied to the affected skin areas in the required amount, rubbing slightly, twice a day. The duration of therapy is determined personally and depends on the severity of the disease. In diseases of the skin of the feet, the average duration of treatment is from two to four weeks. If clinical improvement does not occur, it is necessary to adjust the diagnosis or to correct the treatment regimen. If there are no changes for the better on the skin two weeks after the start of therapy, then the medication is stopped and the doctor is contacted to clarify the diagnosis.
In the treatment of genital infections, the genitals should be lubricated carefully, no more than five days. In any case, consultation with a specialist in skin diseases is required.
Overdose
When using the medication, allergies can develop, including severe burning, skin itching and the development of pruritus.
With prolonged use of the drug, the development of symptoms of hypercorticism is possible. They are manifested in the fact that patients begin to complain of weakness, headaches, weight gain. There are cases in patients with a disease with hypercorticism, a mental disorder occurs, sudden depression, sleep disturbances occur.
Overdose "Akriderm GK", according to patients, is treated by the gradual withdrawal of the drug. With the development of reactions of strong skin sensitivity, the drug should be replaced.
special instructions
During pregnancy, the use of the medication is allowed only in cases where the possible benefits of therapy for the expectant mother significantly exceed the likelihood of negative consequences for the fetus. In such situations, the use of the drug should not be long and limited to tiny areas of the skin. In the first trimester, it is better not to use Akriderm GK, since there is no evidence base on the benefits and harms of the medicine. Refusal from this medication will help eliminate the risk of systemic effects on the unborn child through the blood of a woman. The total effect of the drug on the child in the initial stages of pregnancy automatically increases in the presence of skin lesions of a pregnant woman.
In addition to the possible negative effect on the child with uneven skin, negative effects can be observed in the pregnant woman herself, which can worsen her condition quite strongly. If there is a way to refuse such a medicine before the twelfth week, then the drug is best not to use.
Therapy of skin diseases during gestation should be transferred to the last two trimesters of pregnancy. At this time, the future child has already formed internal organs and systems.
The most optimal period for the use of the drug is the latest stages of pregnancy. In the third trimester, Akriderm GK will no longer have a negative effect on the child. After all, during the last trimester, the baby is already fully formed and is simply gaining weight.
The drug can be prescribed during the bearing of a child to women with allergic and fungal skin diseases of a chronic nature, with their exacerbation. "Akriderm GK" is allowed to be used by a woman. The advantage of its use is a low risk of systemic negative manifestations.
It has not been studied whether the active components of the drug with mother's milk are excreted. If necessary, use, according to the instructions of the Akriderm GK ointment, during the period of natural feeding of the child, it is necessary to switch to artificial mixtures.
The drug can be used in pediatrics, starting from the age of two patients. It is worth noting that it should be used in minor patients with extreme caution. This is due to the fact that the skin area in comparison with the weight of a small child is much larger than in adulthood, and the children have an underdeveloped upper layer of the dermis, which makes it possible to absorb a large amount of active substances, which increases the risk of negative effects. Because of this, the use of the drug in children should be as short as possible. When resistant strains appear, it is necessary to stop the course of use of the medication and make changes to the treatment. In case of poisoning with Akriderm GK, it is required to gradually reduce the dose of the drug until it is canceled with simultaneous therapy according to the symptoms.
Interaction with other drugs
Cases of negative interaction between Akriderma GK and other medicines have not been recorded. But telling the doctor about the medications you are taking is still worth it.
Reviews
You will not find reviews in the instructions of "Akriderma GK"; on forums, consumers leave them mostly positive:
- Many doctors believe that Akriderm GK is nothing more than a lifesaver in the external treatment of dermatoses. It has a quick, pronounced effect, quickly removes swelling in the affected areas.
- ENT doctors, according to reviews, Akriderm GK ointment is considered a very effective drug in the treatment of ENT diseases, especially with abscesses, inflammation of the hair follicles, otitis media. The drug quickly causes an antibacterial effect.
- Dermatologists, judging by the reviews on the instructions for use of "Akriderma GK", often prescribe the drug for dermatitis in large folds: under the breast in women, in the groin, in the area between the toes and hands.
Analogs
The drug Akriderm GK has two main analogues: Kanzinon and Triderm.
"Kanzinon" is an antifungal agent belonging to the group of imidazole derivatives. This is a cheap analogue of Akriderma GK, which can be purchased for only eighty rubles. "Kanzinon", in addition to cream or ointment, can be produced in the form of vaginal cream or tablets. He, like Akriderm GK, treats diseases such as:
- Stomatitis.
- Fungal infection between the fingers.
- Genital infections.
- Lichen (skin disease).
- Fungal paronychia, which is a pathology associated with the development of a purulent-inflammatory process on the skin surrounding the nail.
"Kanzinon" is prohibited for children under two years of age, women during menstruation and at the beginning of pregnancy (first trimester).
Triderm is a medicine for external use on the skin. It is used to treat diseases acquired by an infectious secondary method. The medication is produced in the form of a cream, ointment. Triderm has been shown to be effective in controlling the following diseases:
- Dermatitis.
- Lichen.
- Candidiasis.
- Eczema
- Neurodermatitis.
Triderm is prohibited for use by children under two years of age.
The use of Akriderma GK analogues must be accompanied by confirmation from the attending physician. Given all the contraindications and features of the patient’s disease, you can safely begin treatment of skin diseases.