Surely everyone knows what a strong and painful cough is. It does not allow to lead a normal lifestyle, interferes with communication, sleeping, eating, etc. To eliminate this ailment, many different drugs are produced. One of the most popular and most effective is Bronchorus (tablets). Instructions for use, cost, composition and analogues of this medication will be presented a little lower. You will also learn about in what form the mentioned medication is made.
Form, composition, packaging and description of the drug
The drug "Bronchorus" is sold in the form of cylindrical round white tablets with a bevel. Ambroxol hydrochloride acts as its active ingredient. In addition to it, the drug also includes additional substances in the form of lactose, corn starch, magnesium stearate and talc.
The Bronchorus medication (tablets), the instructions for use of which is contained in a pack of thick paper, is available in blister packs of 10 pieces.
In addition to tablets, the drug in question can be purchased in the form of an oral suspension. Medicinal syrup is a clear liquid that has a yellowish color (may be colorless). Ambroxol hydrochloride is also its active ingredient . As auxiliary components, sodium saccharinate dihydrate, sorbitol, propylene glycol, methyl parahydroxybenzoate, raspberry flavor, propyl parahydroxybenzoate and purified water are used.
You can buy the medicine "Bronchorus" (syrup) in dark glass bottles complete with a spoon.
The mechanism of action of the drug
Do you know how Bronchorus works? The medicine we are considering is an expectorant and mucolytic drug. It has secretolytic and secretomotor properties.
The active substance of this agent is able to stimulate the activity of cilia of the ciliated epithelium, which are located on the bronchial mucosa.
As a result of spiral peristaltic contractions, all mucus is removed from the bronchial tree. We can not say that Ambroxol hydrochloride significantly improves mucociliary transport.
Features of the medication
What features are inherent in the medicine "Bronchorus"? The composition of this medication is such that it is able to stimulate serous cells of the bronchial mucosa, thereby increasing the sputum content and normalizing the disturbed ratio of its components.
Also, the drug in question enhances the release of lysosomes and activates hydrolyzing enzymes, reducing the adhesive properties of mucus and its viscosity. In addition, Ambroxol hydrochloride increases the secretion and synthesis of surface and active substances in the bronchi and alveoli. As a result of this effect, the viscosity of sputum decreases, and the process of expectoration is improved.
After oral administration, Bronchorus begins to act in 20 minutes. The effect of the medication lasts up to 12 hours.
Drug kinetics
The drug "Bronchorus", the price of which is quite reasonable, is quite well absorbed and reaches its maximum concentration in the blood after 2 hours
Communication with plasma proteins is about 80%. The medication quite easily penetrates the placental barrier and through the BBB, and is also excreted in milk.
The drug metabolism is carried out in the liver. In this case, dibromanthranilic acid and glucuronic conjugates are formed.
The half-life of the drug is 10 hours. It is excreted by the kidneys.
Indications for taking the medicine
The drug "Bronchorus", reviews of which are mostly positive, are often used to treat respiratory diseases (acute and chronic), which are accompanied by the formation of viscous sputum:
- pneumonia;
- bronchitis (chronic and acute);
- bronchiectatic disease;
- COPD
- asthma of bronchial, accompanied by difficult discharge of sputum.
Contraindications
Bronchorus tablets are not prescribed for children under 12 years of age. As for the syrup, it can be given to babies younger than the specified age. Also, the medication in question is contraindicated:
- with increased sensitivity to drug substances;
- in the first trimester of pregnancy.
It should also be noted that this drug in the form of tablets is contraindicated for those who have lactose intolerance. As for patients with fructose intolerance, they should not take the medicine in the form of a syrup due to the presence of sorbitol in it.
With extreme caution, "Bronchorus" is prescribed to people with an ulcer or erosion of the digestive tract, liver failure, during lactation and in the second and third trimesters of pregnancy.
The drug "Bronchorus" (tablets): instructions for use
A mucolytic agent is taken only after a meal, washed down with a large volume of liquid.
Adolescents over 12 years of age, as well as adult patients, are prescribed one tablet (i.e. 30 mg) three times a day. If required, it is recommended to take two tablets (i.e. 60 mg) twice a day to enhance the effect (therapeutic).
In severe cases, the indicated dosage is not reduced throughout the course. It is highly recommended not to take the medication in question for more than five days in a row without consulting a doctor.
How to take a suspension of "Bronchorus"?
Syrup is usually prescribed for babies under 12 years old. It should be borne in mind that one dessert spoon (5 ml) of the drug contains 15 mg of ambroxol.
The suspension is taken orally during meals or after a meal. In this case, the suspension is diluted or washed down with a sufficient amount of liquid (1/2 glass of tea, water or juice).
Adults and adolescents over 12 years old in the first 3 days are recommended to take 10 ml of suspension (or 2 dessert spoons) three times a day. After this, the frequency of administration is reduced to two times a day (you can leave the same ratio, but reduce the amount of syrup to 5 ml).
In severe cases, the initial dosage of the drug is not reduced throughout the course of therapy.
For children 5-12 years old, the drug is recommended to be used in an amount of 5 ml three times a day. Children 2-5 years old - 2.5 ml with the same multiplicity, and up to 2 years - 2.5 ml twice a day.
How long should I take Bronchorus? Reviews of experts report that this drug should not be given to a child for more than 4-5 days in a row without consulting a pediatrician.
Treatment of babies 0-2 years old should be carried out only under the supervision of a doctor.
Drinking plenty of fluids is required while taking the drug.
Side effects
Does Bronchorus medication (tablets) cause allergic reactions? The instructions for use say that taking both forms of the drug in question can cause undesirable effects such as a skin rash, angioedema, urticaria, anaphylactic shock and allergic dermatitis. The following reactions are also often observed:
- diarrhea, dry mucous membranes of the respiratory tract, dry mouth, constipation and vomiting;
- gastralgia, rhinorrhea and nausea;
- general weakness, exanthema, headache and dysuria.
Overdose Signs
Taking high doses of the drug can cause unwanted symptoms such as nausea, diarrhea, vomiting, and dyspepsia.
To eliminate such conditions, they cause artificial vomiting, wash the stomach (in the first two hours after poisoning), and also take fatty foods.
Compatibility with other drugs
The combination of the Bronchorus medication with antitussive drugs can lead to difficulty in sputum discharge due to a decrease in cough.
The active substance of the drug in question increases the penetration into the bronchial secretion of “Cefuroxime”, “Amoxicillin”, “Doxycycline” and “Erythromycin”.
Special recommendations
"Bronchorus" in the form of a syrup does not contain sugar. Therefore, patients with a diagnosis of diabetes mellitus can safely prescribe this remedy. However, it should be borne in mind that the composition of the drug suspension includes saccharin and sorbitol.
It is strictly forbidden to combine the drug in question with antitussive drugs, as this can complicate the discharge of sputum.
The preparation in the form of a syrup often causes a laxative effect, since it contains sorbitol.
During treatment with Bronchorus, special care must be taken when engaging in hazardous activities and driving vehicles.
Terms and conditions of storage
Tablets "Bronchorus", the analogues of which are indicated below, must be stored in a dark place and dry place at a temperature of up to +25 degrees. Use this drug should be for three years from the date of production.
As for the syrup, its storage temperature is + 15-18 degrees.
Lactation and pregnancy
If it is necessary to use the drug in the second and third trimesters of pregnancy, it is required to evaluate the expected benefit of the treatment for the mother and the likely risk for the baby.
During lactation, the medication in question should be used with extreme caution, since it is excreted along with milk.
Cost and similar drugs
How much does the Bronchorus medicine cost? The price of this drug depends on the form of release. Syrup in a bottle of 100 ml, you can buy for 40-50 rubles. As for the tablets (20 pieces), they are sold at 20-30 rubles.
If there are contraindications to taking Bronchorus, doctors recommend replacing it with one of the following drugs: Ambrobene, Halixol, AmbroHEXAL, Flavamed, Ambroxol, Fervex for Cough, Ambrolan, Suprima- coffee maker ”,“ Ambrolor ”,“ Remebrox ”,“ Ambrosan ”,“ Neo-Bronchol ”,“ Bronchoxol ”,“ Mukobron ”,“ Vicks Asset AmbroMed ”,“ Medox ”,“ Deflegmin ”,“ Lazongin ”,“ Bronhovern ” , "Lazolvan", "Lazolangin."
Reviews
Reviews on the drug "Bronchorus" leave mostly positive. Consumers report that taking this medication contributes to the rapid discharge of sputum, as well as the elimination of cough.
The main advantage of this tool is its low cost and the ability to treat young children.
Among the disadvantages of the drug in question, frequent side effects are observed that are observed while taking it. According to expert reviews, with allergic and other reactions, the use of the medication should be suspended.